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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BAX

BCL2-associated X protein

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bax, a pro-apoptotic Bcl-2 family member, is a cytosolic protein that changes conformation and translocates to the mitochondria following apoptotic stimuli. It is thought to share significant functional homology with Bak, another pro-apoptotic Bcl-2 family member, as disruption of bax or bak has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking both show decreased apoptotic capability.

Gene Name: BCL2-associated X protein
Family/Subfamily: Apoptosis , Not assigned-Other
Synonyms: BAX, BCL2-associated X protein, Bcl2-L-4, Apoptosis regulator BAX, Bcl-2-like protein 4, BCL2L4
Target Sequences: NM_004324 NP_004315.1 Q07812

Publications (1)

1
Mitochondrial biogenesis fails in secondary biliary cirrhosis in rats leading to mitochondrial DNA depletion and deletions. Arduini A, Serviddio G, Escobar J, Tormos AM, Bellanti F, Via J, Monsalve M, Sastre J. American journal of physiology. Gastrointestinal and liver physiology. 2011 301:G119-27. [PubMed:21415417] Related Antibodies: LS-B1949.

Filtered by: None
Target
BAX (213)
Reactivity
Human (174)
Mouse (108)
Rat (87)
Bat (9)
Bovine (24)
Chimpanzee (1)
Dog (25)
Gerbil (3)
Gibbon (3)
Goat (2)
Hamster (5)
Horse (5)
Monkey (33)
Orangutan (3)
Pig (34)
Rabbit (7)
Sheep (6)
Application
IHC (90)
IHC-Fr (7)
IHC-P (42)
WB (186)
Flo (14)
ELISA (72)
ICC (9)
IF (58)
IP (42)
Peptide-ELISA (8)
Host
rabbit (143)
mouse (68)
goat (1)
sheep (1)
Isotype
IgG (69)
IgG1 (39)
IgG1,k (14)
IgG2a (2)
IgG2b (9)
IgG2b,k (2)
Clonality
monoclonal mc (67)
polyclonal pc (144)
recombinant monoclonal rmc (2)
Clone
1D1 (1)
1F5-1B7 (1)
2D2 (8)
4F11 (1)
4H9B11 (1)
557CT5.2.1 (6)
5B7 (2)
6A7 (7)
ARBX-1 (3)
BAX/962 (3)
E63 (2)
G1/G1-4 (2)
G26-R (1)
GF1 (1)
SPM336 (2)
Format
AP Conjugated (7)
APC (4)
APC Conjugated (11)
Azide-free (10)
Biotin Conjugated (18)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
DY488 Conjugated (1)
DY550 Conjugated (1)
FITC Conjugated (15)
HRP Conjugated (14)
Magnetic beads Conjugated (1)
PE Conjugated (11)
Ready-to-Use (4)
Sepharose Conjugated (1)
Unconjugated (125)
Epitope
N-Terminus (23)
aa28-56 (17)
aa1-192 (10)
aa41-76 (8)
aa69-98 (8)
aa51-100 (4)
aa3-16 (3)
aa43-61 (3)
110-190 aa (2)
120-200 aa (2)
Internal (2)
aa43-60 (2)
pThr167 (2)
1-80 aa, N-terminal (1)
10-90 aa, Internal (1)
10-90 aa, N-terminal (1)
30-110 aa, Internal (1)
C-Terminus (1)
Cys62 (1)
Ser163 (1)
Ser4 (1)
aa1-50 (1)
aa10-59 (1)
aa100-170 (1)
aa12-24 (1)
aa133-182 (1)
aa143-192 (1)
aa15 (1)
aa19-33 (1)
aa41-90 (1)
aa44-62 (1)
aa47-78 (1)
aa68-81 (1)
aa8-16 (1)
aa80-129 (1)
pSer184 (1)
Publications
No (212)
Yes (1)
Showing 1-25 of 213 results

BAX Antibody (N-Terminus) IHC-plus™ LS-B1949
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Mouse BAX
Mouse, Rat, Human
IHC IHC-P IP WB
Unconjugated
50µl  $425.00
Anti-BAX antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Hela cell extract was resolved by electrophoresis, transferred to nitrocellulose, and probed with rabbit anti-Bax polyclonal antibody. Proteins were visualized using a donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence system.

BAX Antibody (clone 6A7) IHC-plus™ LS-B2510
Mouse Monoclonal [clone 6A7] (IgG1) to Human BAX
Mouse, Rat, Human, Monkey
IHC IHC-P IP
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-BAX antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Extracts from Hela cell lysate was immunoprecipitated with clone 6A7 (lane 1), 4 ug purified monoclonal antibody without cell lysate (clone 6A7, lane 2), or Hela cell lysate without immunoprecipitation (lane 3) were resolved by electrophoresis, transferred to nitrocellulose, and probed with anti-Bax polyclonal antibody.

BAX Antibody (aa41-76) IHC-plus™ LS-B11818
Rabbit Polyclonal to Human BAX
Mouse, Human
Flo IHC IHC-P WB
Unconjugated
200µl  $425.00
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Bax Antibody(BH3)western blot of HL-60 cell line lysates (35 ug/lane). The Bax antibody detected the Bax protein (arrow).

BAX Antibody LS-C63137
Rabbit Polyclonal to Human BAX
Rabbit, Mouse, Bovine, Rat, Pig, Human, Monkey
WB
Unconjugated
50µg 1mg/ml  $275.00; 200µg 1mg/ml  $435.00

BAX Antibody IHC-plus™ LS-B1333
Rabbit Polyclonal (IgG) to Human BAX
Human
ELISA ICC IF IHC IHC-P IP WB
Unconjugated
0.05mg 1mg/ml  $425.00
Anti-BAX antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.
Immunocytochemistry staining of HL-60 cells using Bax at 2 ug/ml.

BAX Antibody (aa43-60) LS-C148225
Rabbit Polyclonal to Mouse BAX
Mouse, Rat
IHC IHC-Fr IHC-P IP WB
Unconjugated
50µl  $335.00
Formalin-fixed, paraffin-embedded mouse tissue sections stained for Bax using Polyclonal Antibody to Bax at 1:2000. A. Pancreas. B. Brain showing expression of Bax in the Purkinje cells.
Western blot of Bax in mouse using Polyclonal Antibody to Bax at 1:2000. 1. In vitro translated mouse Bax. 2. Normal cortex. 3. Ischemic hippocampus. 4. Ischemic hippocampus. Ischemic samples were prepared 6 hr post middle cerebral artery occlusion. The results show the Bax expression increased following ischemia.

BAX Antibody (clone 2D2) LS-C41062
Mouse Monoclonal [clone 2D2] (IgG1) to Human BAX
Human
IHC IP WB
Unconjugated
100µg 0.5mg/ml  $285.00
Western blot of extracts from HeLa cells (lane 1) and human PBMCs (lane 2) using anti-Bax, clone 2D2.

BAX Antibody (aa1-50) IHC-plus™ LS-B6546
Rabbit Polyclonal (IgG) to Human BAX
Mouse, Rat, Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-BAX antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Immunofluorescence of A549 cells, using BAX Antibody. The picture on the right is treated with the synthesized peptide.

BAX Antibody (clone 1D1) LS-C107441
Mouse Monoclonal [clone 1D1] (IgG1,k) to Rat BAX
Rat
IP WB
Unconjugated
100µg 0.5mg/ml  $295.00

BAX Antibody (clone 2D2) LS-C357719
Mouse Monoclonal [clone 2D2] (IgG1) to Human BAX
Dog, Pig, Orangutan, Human, Monkey
ELISA Flo IF IHC IHC-P IP WB
Unconjugated
20µg 0.2mg/ml  $295.00; 100µg 0.2mg/ml  $465.00
Bax antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BAX Antibody (clone 2D2, Azide-free) LS-C389431
Mouse Monoclonal [clone 2D2] (IgG1) to Human BAX
Dog, Pig, Orangutan, Human, Monkey
ELISA Flo IF IHC IHC-P IP WB
Unconjugated, Azide-free
100µg 1mg/ml  $465.00
Bax antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BAX Antibody (clone 2D2, Ready-to-Use) LS-C389429
Mouse Monoclonal [clone 2D2] (IgG1) to Human BAX
Dog, Pig, Orangutan, Human, Monkey
ELISA Flo IF IHC IHC-P IP WB
Unconjugated, Ready-to-Use
7ml  $465.00
Bax antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BAX Antibody (clone 2D2) LS-C88389
Mouse Monoclonal [clone 2D2] (IgG1,k) to Human BAX
Dog, Bovine, Pig, Human, Monkey
IF IHC IHC-P WB
Unconjugated
100µl 200µg/ml  $315.00; 500µl 200µg/ml  $635.00; 1ml 200µg/ml  $980.00
Formalin-fixed, paraffin-embedded human Hodgkin's lymphoma stained with peroxidase-conjugate and DAB chromogen. Note membrane staining of Reed-Sternberg cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BAX Antibody (clone G26-R) IHC-plus™ LS-B10199
Rabbit Polyclonal [clone G26-R] to Human BAX
Mouse, Rat, Human
ELISA ICC IHC IHC-Fr IHC-P IP WB
Unconjugated
50µl  $425.00
Anti-BAX antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

BAX Antibody (N-Terminus) LS-C351881
Rabbit Polyclonal to Human BAX
Dog, Bovine, Pig, Human
ELISA IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of BAX staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of BAX expression in MCF7 (A); HeLa (B); A431 (C); HEK293T (D); Raw264.7 (E); rat brain (F) whole cell lysates.

BAX Antibody LS-C192605
Rabbit Polyclonal to Human BAX
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
100µl  $385.00
Immunohistochemistry (IHC) analysis of Bax pAb in paraffin-embedded Lymphoma tissue.
Western blot of Bax pAb in extracts from 7901, Hela, NB4, Raw264.7 cells and mouse liver tissue.

BAX Antibody (clone 4F11) LS-C179751
Mouse Monoclonal [clone 4F11] (IgG2b,k) to Human BAX
Human
Flo ICC IHC IHC-P IP WB
Unconjugated
100µg 100µl 1mg/ml  $345.00
Immunohistochemistry Image
Immunocytochemistry Image

BAX Antibody LS-C661935
Rabbit Polyclonal to Human BAX
Human
Flo ICC IHC IHC-P WB
Unconjugated
100µg  $355.00
Bax was detected in paraffin-embedded sections of mouse intestine tissues using rabbit anti- Bax Antigen Affinity purified polyclonal antibody
Bax was detected in paraffin-embedded sections of rat intestine tissues using rabbit anti- Bax Antigen Affinity purified polyclonal antibody

BAX Antibody (Internal) LS-C351882
Rabbit Polyclonal to Human BAX
Bovine, Rat, Pig, Human
ELISA ICC IF IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of BAX staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of BAX staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

BAX Antibody (aa3-16) LS-C26453
Mouse Monoclonal (IgG1) to Human BAX
Human
WB
Unconjugated
100µg 1mg/ml  $365.00

BAX Antibody (Internal) LS-C353915
Rabbit Polyclonal to Human BAX
Mouse, Sheep, Bovine, Rat, Pig, Human
ICC IF IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of BAX staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of BAX staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

BAX Antibody LS-C747226
Rabbit Polyclonal (IgG) to Human BAX
Mouse, Rat, Human
IF IHC IP WB
Unconjugated
50µl  $235.00
Immunohistochemistry of paraffin-embedded rat testis using BAX antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse testis using BAX antibody at dilution of 1:100 (40x lens).

BAX Antibody (N-Terminus) LS-C127000
Rabbit Polyclonal (IgG) to Human BAX
Rabbit, Mouse, Rat, Human
WB
Unconjugated
100µg  $530.00

BAX Antibody (aa44-62) LS-C3482
Rabbit Polyclonal (IgG) to Human BAX
Human, Monkey
WB
Unconjugated
50µg  $415.00; 200µg  $680.00

BAX Antibody (clone BAX/962, Azide-free) LS-C390893
Mouse Monoclonal [clone BAX/962] (IgG1) to Human BAX
Human, Monkey
Flo IF IHC IHC-P WB
Unconjugated, Azide-free
100µg 1mg/ml  $465.00
Formalin-fixed, paraffin-embedded Hodgkin's lymphoma stained with Bax antibody (BAX/962).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human melanoma stained with Bax antibody (BAX/962).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Showing 1-25 of 213 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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