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Anti-ADAM10 Antibody (clone 163003, APC) LS-C124901

Ordering

Wt. Vol. Conc. Price
- 100 tst - $635
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ADAM10 Antibodies

Anti-ADAM10 Antibody (C-Terminus, clone EPR5622) IHC-plus™ LS-B7688
Rabbit Monoclonal [clone EPR5622] to Human ADAM10
Human, Mouse, Rat
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-ADAM10 Antibody (aa420-641, Biotin) LS-C300616
Rabbit Polyclonal (IgG) to Human ADAM10
Human
IHC - Paraffin, Western blot, ELISA
Biotin Conjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 163003] (IgG2b) to Human ADAM10
Human
Flow Cytometry
APC Conjugated

Details

Human ADAM10
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [163003]
Allophycocyanin
Purified
Unmodified

Applications

Flow Cytometry

Specificity and Use

ADAM10 antibody was raised against mouse myeloma cell line NS0-¬derived recombinant human ADAM10 (aa Thr214 - Glu672; UniProt Accession #O14672).
Recognizes human ADAM10 (APC).
Suitable for use in Flow Cytometry Flow Cytometry: Intracellular staining antibodies are designed for multiparameter flow cytometric analysis of cells. To stain for surface proteins (e. g. CD3, CD4, CD8) in addition to the intracellular protein, we recommend that the investigator determine whether the fixation and permeabilization steps adversely affect the surface protein. If so, surface staining of cells prior to fixation and permeabilization is recommended. For intracellular staining, cells must first be fixed and permeabilized. Use of 4% paraformaldehyde in PBS as a fixative is recommended. Other formulations or tissue fixatives may affect the staining properties of the monoclonal antibody. For permeabilization, 0.1% saponin in a balanced salt solution is effective in facilitating antibody entry into cells. Due to the reversible nature of cell membrane permeabilization, saponin must be included in all buffers used (i. e. both the staining and washing steps). 10ul of undiluted product can be used to stain 1 x 10e6 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized from 25 ug antibody, 1 ml PBS, 0.1% sodium azide
100 tst 40-50% glycerol, PBS.
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C.
For research use only.

About ADAM10

O14672 NM_001110 NP_001101.1

ADAM10 Antibody, AD10 Antibody, ADAM 10 Antibody, Kuzbanian Antibody, HsT18717 Antibody, CD156c Antibody, CD156c antigen Antibody, CDw156 Antibody, Kuz Antibody, Kuzbanian protein homolog Antibody, MADM Antibody

Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein.

Requested From: United States
Date Requested: 12/7/2016

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