Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ACCN3 / ASIC3 antibody was raised against synthetic peptide 21aa sequence near the cytoplasmic C-terminus of rat DRASIC (KLH coupled).
Recognizes rat Acid Sensitive Ion Channel 3 (ASIC3), Dorsal Root Ganglion ASIC (DRASIC). No significant sequence homology with other ASICs. Species sequence homology: human: 95%; human testis specific DRASIC homolog hTNaCl: 90%.
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000 using ECL. ELISA: 1:10000-1:50000. Coat ELISA plates at 1 ug/ml with Control Peptide.
Neat serum, 0.05% sodium azide, 40% glycerol.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
ACCN3 / ASIC3 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes.