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ACCN3 / ASIC3 Antibody (C‑Terminus) LS‑C11724
ASIC3 antibody LS-C11724 is an unconjugated rabbit polyclonal antibody to rat ASIC3 (ACCN3). Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C11724-100
100 µl
$725

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ACCN3 / ASIC3 antibody LS-C31243 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: IHC, IHC - Paraffin, Western blot
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Applications: IHC, Western blot
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Product Description

ASIC3 antibody LS-C11724 is an unconjugated rabbit polyclonal antibody to rat ASIC3 (ACCN3). Validated for ELISA and WB.
About ACCN3 / ASIC3
ACCN3 / ASIC3 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. Q9UHC3 NM_020321 NP_064717.1

ASIC3 Antibody, Acid-sensing ion channel 3 Antibody, Acid-sensing ion channel Antibody, ACCN3 Antibody, HASIC3 Antibody, HTNaC1 Antibody, Modulatory subunit of ASIC2a Antibody, SLNAC1 Antibody, DRASIC Antibody, Testis sodium channel 1 Antibody, TNaC1 Antibody


Specifications

Target
Rat ACCN3 / ASIC3
Host
Rabbit
Reactivity
Rat (tested or 100% immunogen sequence identity)
Predicted
Human (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:50000)
Immunogen
ACCN3 / ASIC3 antibody was raised against synthetic peptide 21aa sequence near the cytoplasmic C-terminus of rat DRASIC (KLH coupled).
Epitope
C-Terminus
Specificity
Recognizes rat Acid Sensitive Ion Channel 3 (ASIC3), Dorsal Root Ganglion ASIC (DRASIC). No significant sequence homology with other ASICs. Species sequence homology: human: 95%; human testis specific DRASIC homolog hTNaCl: 90%.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000 using ECL. ELISA: 1:10000-1:50000. Coat ELISA plates at 1 ug/ml with Control Peptide.
Presentation
Neat serum, 0.05% sodium azide, 40% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/18/2018

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