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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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ACCN3 / ASIC3

acid-sensing (proton-gated) ion channel 3

ACCN3 / ASIC3 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.

Gene Name: acid-sensing (proton-gated) ion channel 3
Family/Subfamily: Ion Channel , Sodium channel - amiloride-sensitive
Synonyms: ASIC3, Acid-sensing ion channel 3, Acid-sensing ion channel, ACCN3, HASIC3, HTNaC1, Modulatory subunit of ASIC2a, SLNAC1, DRASIC, Testis sodium channel 1, TNaC1
Target Sequences: NM_020321 NP_064717.1 Q9UHC3

Viewing 1-22 of 22 items
ACCN3 / ASIC3 Antibody - ACCN3 / ASIC3 antibody ARP35152_T100-NP_004760-ACCN3 (amiloride-sensitive cation channel 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Human
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $335.00
ACCN3 / ASIC3 Antibody - ACCN3 / ASIC3 antibody ARP35152_T100-NP_004760-ACCN3 (amiloride-sensitive cation channel 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human
IHC, IHC-P, WB
HRP Conjugated
100µl   0.65mg/ml   $355.00
ACCN3 / ASIC3 Antibody - ACCN3 / ASIC3 antibody ARP35152_T100-NP_004760-ACCN3 (amiloride-sensitive cation channel 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human
IHC, IHC-P, WB
Biotin Conjugated
100µl   1mg/ml   $355.00
ACCN3 / ASIC3 Antibody - ACCN3 / ASIC3 antibody ARP35152_T100-NP_004760-ACCN3 (amiloride-sensitive cation channel 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Chimpanzee, Human
IHC, IHC-P, WB
FITC Conjugated
100µl   1mg/ml   $355.00
Select
Rabbit Polyclonal (IgG) to Rat ACCN3 / ASIC3
Mouse, Rat
IHC, WB
Unconjugated
500µg   $325.00
ACCN3 / ASIC3 Antibody - WB of ACCN3 / ASIC3 antibody. Lane 1: Rat Brain Tissue Lysate. Lane 2: Rat Testis Tissue Lysate. Lane 3: U87 Cell Lysate. Lane 4: NEURO Cell Lysate. Lane 5: SMMC Cell Lysate.
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Rabbit Polyclonal to Human ACCN3 / ASIC3
Mouse, Rat, Human, Monkey
WB
Unconjugated
100µg   200µl   0.5mg/ml   $305.00
ACCN3 / ASIC3 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution 1:100
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Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $235.00; 100µl   $285.00
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Human
ELISA, WB
PE Conjugated
200µl   $740.00
ACCN3 / ASIC3 Antibody - Western blot analysis of lysate from HepG2 cells, using ASIC3 Antibody.
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Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Human
ELISA, WB
Unconjugated
50µg   1mg/ml   $265.00; 100µg   1mg/ml   $325.00
ACCN3 / ASIC3 Antibody - Western blot of ASIC3 antibody
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Human
ELISA, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Guinea pig Polyclonal (IgG) to Rat ACCN3 / ASIC3
Rat
ICC, IHC
Unconjugated
50µl   $445.00
Select
Rabbit Polyclonal (IgG) to Rat ACCN3 / ASIC3
Rat
ELISA, WB
Unconjugated
100µg   $755.00
Select
Rabbit Polyclonal (IgG) to Rat ACCN3 / ASIC3
Rat
ELISA, WB
Unconjugated
100µl   $725.00
ACCN3 / ASIC3 Antibody - ACCN3 Antibody western blot of CEM cell line lysates (35 ug/lane). The ACCN3 antibody detected the ACCN3 protein (arrow).
Select
Rabbit Polyclonal to Human ACCN3 / ASIC3
Human
WB
Unconjugated
400µl   $325.00
ACCN3 / ASIC3 Antibody - Rabbit antibody to ASIC3 (500-531). WB on mouse muscle lysate. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:1000 incubated at 4C overnight.
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Rabbit Polyclonal to Human ACCN3 / ASIC3
Mouse, Rat, Human
WB
Unconjugated
100µl   $325.00
ACCN3 / ASIC3 Antibody - Western blot analysis of extracts of various cell lines, using ASIC3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Select
Rabbit Polyclonal (IgG) to Human ACCN3 / ASIC3
Mouse, Rat
WB
Unconjugated
50µl   $235.00; 100µl   $295.00; 200µl   $385.00

Viewing 1-22 of 22 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).