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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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A2M / Alpha‑2‑Macroglobulin Antibody (HRP) LS‑C187665
Alpha-2-Macroglobulin antibody LS-C187665 is an HRP-conjugated sheep polyclonal antibody to human Alpha-2-Macroglobulin (A2M). Validated for ELISA, ID and IHC.
Catalog
Size
Price
LS-C187665-1000
1000 µl (1 mg/ml)
Unavailable

Popular A2M / Alpha-2-Macroglobulin Products

Antibody
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Applications: ELISA, Immunoelectrophoresis
Anti-A2M / Alpha-2-Macroglobulin antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B403 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA
Anti-A2M / Alpha-2-Macroglobulin antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3119 concentration 10 ug/ml.
Species: Human, Rat
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Antibody
Species: Human
Applications: ICC, Western blot

Product Description

Alpha-2-Macroglobulin antibody LS-C187665 is an HRP-conjugated sheep polyclonal antibody to human Alpha-2-Macroglobulin (A2M). Validated for ELISA, ID and IHC.
About A2M / Alpha-2-Macroglobulin
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). P01023 NM_000014 NP_000005.2

A2M Antibody, CPAMD5 Antibody, A2MD Antibody, FWP007 Antibody, Alpha-2-M Antibody, Alpha-2-macroglobulin Antibody, S863-7 Antibody


Specifications

Target
Human A2M / Alpha-2-Macroglobulin
Host
Sheep
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Horseradish Peroxidase
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen (1:50 - 1:500)
  • ELISA (1:50 - 1:500)
  • Immunodiffusion
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Native alpha-2-macroglobulin from serum.
Specificity
Recognizes human alpha-2-macroglobulin, a secreted protease inhibitor known to suppress the function of all four classes of proteinases. Exhibits minimal cross reactivity with related serum proteins.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.01% Thimerosal, HRP stabilizer
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Enzyme-Linked Immunosorbent Assay

Human alpha-2 Macroglobulin detected with Sheep anti-alpha-2 Macroglobulin:HRP This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human alpha-2 Macroglobulin detected with Sheep anti-alpha-2 Macroglobulin:HRP This image was taken for the unconjugated form of this product. Other forms have not been tested.

Enzyme-Linked Immunosorbent Assay

Human alpha-2 Macroglobulin detected with Sheep anti-alpha-2 Macroglobulin:HRP This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human alpha-2 Macroglobulin detected with Sheep anti-alpha-2 Macroglobulin:HRP This image was taken for the unconjugated form of this product. Other forms have not been tested.

Enzyme-Linked Immunosorbent Assay

Human alpha-2 Macroglobulin detected with Sheep anti-alpha-2 Macroglobulin:HRP This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human alpha-2 Macroglobulin detected with Sheep anti-alpha-2 Macroglobulin:HRP This image was taken for the unconjugated form of this product. Other forms have not been tested.

Enzyme-Linked Immunosorbent Assay

Human alpha-2 Macroglobulin detected with Sheep anti-alpha-2 Macroglobulin:HRP This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human alpha-2 Macroglobulin detected with Sheep anti-alpha-2 Macroglobulin:HRP This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/17/2018

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