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VAV3

vav 3 guanine nucleotide exchange factor

Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2 (ITGB2)-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3 (ITGB3)-mediated adhesion. Does not affect integrin beta-1 (ITGB1)-mediated adhesion.

Gene Name: vav 3 guanine nucleotide exchange factor
Synonyms: VAV3, VAV-3, Vav 3 oncogene
Target Sequences: NM_006113 NP_006104.4 Q9UKW4

☰ Filters
Antibodies (45)
Proteins (8)
ELISA Kits (5)
Cell-Based (1)
Over-Expression Lysate (4)
Primary (45)
Recombinant (4)
Sandwich (4)
VAV3 (58)
Human (48)
Mouse (18)
Rat (1)
Monkey (2)
IHC (12)
IHC-P (2)
WB (42)
ELISA (11)
ICC (7)
IP (8)
Peptide-ELISA (3)
rabbit (44)
goat (1)
Product Group
IHCPlus (2)
IgG (23)
polyclonal pc (45)
96-Well Microplate (1)
96-Well Strip Plate (4)
AP Conjugated (1)
APC (2)
APC Conjugated (3)
Biotin Conjugated (4)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (22)
aa183-380 (8)
aa398-583 (8)
pTyr173 (4)
110-190 aa (2)
Internal (1)
aa118-167 (1)
aa200-250 (1)
aa566-591 (1)
aa567-578 (1)
aa768-802 (1)
p173 (1)
No (58)
Adherent Cell Cultures (1)
Plasma (4)
Serum (4)
Tissue Homogenates (2)
His (2)
Myc-DDK (Flag) (6)
Human (6)
293T Cells (2)
E. coli (2)
HEK 293 Cells (4)
VAV3 Antibody - Anti-VAV3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
VAV3 Goat anti-Human Polyclonal (aa567-578) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$440
Select
VAV3 Rabbit anti-Human Polyclonal (aa566-591) Antibody
Human, Monkey
ICC, IHC, IP, WB
Unconjugated
200 µg/$702
Select
VAV3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ICC, IHC, IP, WB
HRP Conjugated
100 µl/$833
Select
VAV3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ICC, IHC, IP, WB
Biotin Conjugated
100 µl/$833
Select
VAV3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ICC, IHC, IP, WB
FITC Conjugated
100 µl/$833
Select
VAV3 Rabbit anti-Human Polyclonal (AP) Antibody
Human
ICC, IHC, IP, WB
AP Conjugated
100 µl/$833
Select
VAV3 Rabbit anti-Human Polyclonal (APC) Antibody
Human
ICC, IHC, IP, WB
APC Conjugated
100 µl/$833
Select
VAV3 Rabbit anti-Human Polyclonal (PE) Antibody
Human
ICC, IHC, IP, WB
PE Conjugated
100 µl/$833
VAV3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$746
VAV3 Protein - Recombinant Vav 3 Oncogene By SDS-PAGE
Select
E. coli
His
24.7 kDa
10 µg/$329; 50 µg/$765; 100 µg/$1,129; 200 µg/$1,306; 1 mg/$3,073; 500 µg/$2,189; 5 mg/$7,050
VAV3 Antibody - Immunohistochemistry of paraffin-embedded human pancreatic tissue using VAV3 Antibody at dilution of 1:100
Select
VAV3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$284; 100 µg/$348
VAV3 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.
Select
VAV3 Rabbit anti-Human Polyclonal (aa200-250) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$485
VAV3 Antibody - Western blot of recombinant VAV3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
VAV3 Rabbit anti-Human Polyclonal (aa183-380) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$341; 500 µl/$481; 1 ml/$551
VAV3 Antibody - Western blot analysis of extracts from Jurkat cells, using VAV3 (Ab-173) antibody.
Select
VAV3 Rabbit anti-Human Polyclonal (p173) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$347
VAV3 Antibody - Western blot of Phospho-Vav3 (Y173) antibody
Select
VAV3 Rabbit anti-Human Polyclonal (110-190 aa) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µl/$279; 100 µl/$309; 200 µl/$379
Select
VAV3 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µl/$556
Select
VAV3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$318; 100 µg/$378
VAV3 Antibody - Western blot analysis on JK cell lysates using Phospho-VAV3(Tyr173) antibody. The lane on the left is treated with the antigen-specific peptide.
Select
VAV3 Rabbit anti-Human Polyclonal (pTyr173) Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µl/$369; 200 µl/$411
VAV3 Antibody - Western blot analysis of extracts from JK cells, using VAV3 (Phospho-Tyr173) antibody.
Select
VAV3 Rabbit anti-Human Polyclonal (pTyr173) Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$347
VAV3 Antibody - Western blot of Vav3 antibody
Select
VAV3 Rabbit anti-Human Polyclonal (110-190 aa) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µl/$279; 100 µl/$309; 200 µl/$379
VAV3 Antibody - Anti-VAV3 Antibody at 1:2000 dilution + human kidney lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 98 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Select
VAV3 Rabbit anti-Human Polyclonal (aa768-802) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$376
VAV3 Antibody - Western blot analysis of the lysates from HepG2 cells using VAV3 antibody.
Select
VAV3 Rabbit anti-Human Polyclonal (aa118-167) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$318; 100 µl/$378
Select
VAV3 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$580
Select
VAV3 Rabbit anti-Human Polyclonal (pTyr173) Antibody
Mouse, Human
WB
Unconjugated
10 Blots/$674
Select
VAV3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$280; 120 µl/$343; 200 µl/$451
Viewing 1-25 of 58 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).