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Catalog Number Size Price
LS-C502148-50 50 µg $284 
LS-C502148-100 100 µg (5 mg/ml) $348 
VAV3 Antibody - Immunohistochemistry of paraffin-embedded human pancreatic tissue using VAV3 Antibody at dilution of 1:100
VAV3 Antibody - Positive WB detected in:Mouse kidney tissue,Rat lung tissue;All lanes:VAV3 antibody at 2.5?g/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 98,87,33,101 KDa;Observed band size: 98 KDa;
VAV3 Antibody - Immunohistochemistry of paraffin-embedded human pancreatic tissue using VAV3 Antibody at dilution of 1:100
VAV3 Antibody - Positive WB detected in:Mouse kidney tissue,Rat lung tissue;All lanes:VAV3 antibody at 2.5?g/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 98,87,33,101 KDa;Observed band size: 98 KDa;
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Polyclonal Rabbit anti‑Human VAV3 Antibody (IHC, WB) LS‑C502148

Polyclonal Rabbit anti‑Human VAV3 Antibody (IHC, WB) LS‑C502148

Antibody:
VAV3 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, WB, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$284
LS-C502148-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
VAV3 Rabbit anti-Human Polyclonal Antibody
Application:
IHC, WB, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
VAV3 antibody LS-C502148 is an unconjugated rabbit polyclonal antibody to VAV3 from human. It is reactive with human, mouse and rat. Validated for ELISA, IHC and WB.
Target
Human VAV3
Synonyms
VAV3 | VAV-3 | Vav 3 oncogene
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with FITC, Biotin, HRP.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Guanine nucleotide exchange factor VAV3 protein (562-674AA)
Specificity
Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2 (ITGB2)-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3 (ITGB3)-mediated adhesion. Does not affect integrin beta-1 (ITGB1)-mediated adhesion (By similarity).
Applications
  • IHC
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About VAV3
Q9UKW4 NM_006113 NP_006104.4

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/25/2022