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UBE2L6

ubiquitin-conjugating enzyme E2L 6

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: ubiquitin-conjugating enzyme E2L 6
Synonyms: UBE2L6, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, UBCH8, RIG-B
Target Sequences: NM_004223 NP_004214.1 O14933

Publications (1)

1
Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha. Krmer OH, Mller S, Buchwald M, Reichardt S, Heinzel T. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2008 22:1369-79. [PubMed:18073335] Related Antibodies: LS-C99504.

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Products
Antibodies (31)
Primary (31)
UBE2L6 (31)
Human (31)
Mouse (7)
Rat (3)
Chimpanzee (6)
Gibbon (3)
Monkey (8)
Pig (4)
Rabbit (4)
IHC (10)
IHC-P (2)
WB (24)
ELISA (17)
IF (2)
IP (1)
rabbit (28)
mouse (3)
Product Group
IHCPlus (1)
IgG (23)
IgG2b,k (2)
monoclonal mc (3)
polyclonal pc (28)
K1H3 (1)
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (16)
aa123-153 (8)
C-Terminus (4)
aa38-87 (4)
aa1-152 (2)
No (30)
Yes (1)
UBE2L6 Antibody - Anti-UBE2L6 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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UBE2L6 Mouse anti-Human Monoclonal (aa1-152) (K1H3) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$440
UBE2L6 Antibody - Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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UBE2L6 Rabbit anti-Human Polyclonal (aa123-153) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$381
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UBE2L6 Mouse anti-Human Monoclonal (aa1-152) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$512
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UBE2L6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$341
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UBE2L6 Rabbit anti-Human Polyclonal (aa123-153) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$653
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UBE2L6 Rabbit anti-Human Polyclonal (aa123-153) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$828
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UBE2L6 Rabbit anti-Human Polyclonal (aa123-153) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$828
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UBE2L6 Rabbit anti-Human Polyclonal (aa123-153) (AP) Antibody
Human
ELISA, IHC, WB
AP Conjugated
200 µl/$828
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UBE2L6 Rabbit anti-Human Polyclonal (aa123-153) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$828
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UBE2L6 Rabbit anti-Human Polyclonal (aa123-153) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$828
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UBE2L6 Rabbit anti-Human Polyclonal (aa123-153) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$828
UBE2L6 Antibody - Immunofluorescent analysis of Hela cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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UBE2L6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$284; 100 µg/$348
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UBE2L6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
50 µl/$275; 100 µl/$312; 200 µl/$350
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UBE2L6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$347
UBE2L6 Antibody - Western blot analysis UBE2L6 using K562 whole cells lysates
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UBE2L6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$369; 200 µl/$411
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UBE2L6 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
50 µl/$275; 100 µl/$312; 200 µl/$350
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UBE2L6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µl/$290; 100 µl/$350
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UBE2L6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$275; 200 µl/$312; 400 µl/$350
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UBE2L6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$280; 120 µl/$343; 200 µl/$451
UBE2L6 Antibody - Western blot analysis of extracts of various cell lines, using UBE2L6 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 5s.
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UBE2L6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
UBE2L6 Antibody - MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBE2L6 Rabbit anti-Human Polyclonal (aa38-87) Antibody
Rabbit, Pig, Human, Monkey
WB
Unconjugated
100 µl/$414
UBE2L6 Antibody - MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBE2L6 Rabbit anti-Human Polyclonal (aa38-87) (HRP) Antibody
Rabbit, Pig, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$459
UBE2L6 Antibody - MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBE2L6 Rabbit anti-Human Polyclonal (aa38-87) (Biotin) Antibody
Rabbit, Pig, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$459
UBE2L6 Antibody - MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBE2L6 Rabbit anti-Human Polyclonal (aa38-87) (FITC) Antibody
Rabbit, Pig, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$459
UBE2L6 Antibody - UBE2L6 antibody Western blot of Fetal Small Intestine lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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UBE2L6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human, Monkey
WB
Unconjugated
100 µl/$414
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).