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TSPAN7 / CD231 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.
Gene Name: | tetraspanin 7 |
Family/Subfamily: | Tetraspan , not assigned-Tetraspan |
Synonyms: | TSPAN7, A15, CD231 antigen, Cell surface glycoprotein A15, CD231, DXS1692E, MXS1, TALLA-1, Tetraspanin 7, Transmembrane protein A15, Tetraspanin protein, Tspan-7, TM4SF2, CCG-B7, MRX58, Tetraspanin-7, TM4SF2b, Transmembrane 4 superfamily 2b |
Target Sequences: | NM_004615 NP_004606.2 P41732 |
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