TNFRSF14 / CD270 / HVEM

tumor necrosis factor receptor superfamily, member 14

HVEM (Herpes virus entry mediator) is a member of the tumor necrosis factor receptor family. This family of receptors plays a central role in the development of the immune system. HVEM has been shown to mediate HSV entry into activated T cells, in addition to modulating the activation of nuclear factor NF-kB (a transcriptional activator of multiple immuno modulatory and inflammatory genes) and transcription factor AP-1 (a regulator of cellular stress-response genes). Binding by HVEM of the ligand LIGHT induces receptor down regulation. Degradation or release of LIGHT by matrix metalloproteinases then contributes to the return to baseline levels for both LIGHT and HVEM. Soluble HVEM, which tends to form disulfide-linked heterodimeric complexes in solution, can act as a “receptor decoy” resulting in inhibition of the activity of the HVEM ligands, LIGHT and TNF-beta.

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Products

Proteins (23)

Type

Over-Expression Lysate (2)

Recombinant (21)

Target

TNFRSF14 / CD270 / HVEM (23)

Publications

No (23)

Tag

DDK (Flag)-His, C-terminus (1)

Fc, C-terminus (5)

Fc/His,C-terminus (1)

GST (1)

His (2)

His, C-Terminal (1)

His, N-Terminal (1)

His,C-terminus (2)

His-T7 (1)

mFc, C-terminus (1)

Myc-DDK (Flag) (3)

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Species

Human (15)

Monkey-Rhesus (2)

Mouse (5)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (4)

High Five Cells (1)

Human (2)

Human Cells (1)

Insect Cells (1)

Mammalian Cells (7)

Sf9 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (13)

Biologically Active

Biologically active (4)

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant His) - LS-G2669

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Monkey-Rhesus TNFRSF14 / CD270 / HVEM Protein (Recombinant His,C-terminus) (Leu39-Val203) - LS-G138813

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

18.3 kDa

Price:

10 µg/$350; 50 µg/$407

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Mouse TNFRSF14 / CD270 / HVEM Protein (Recombinant His) (aa45-262) - LS-G15401

Source:

E. coli

Tag:

His

Molecular Weight:

25.4 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant) - LS-G137597

Source:

Insect Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein.

Molecular Weight:

The 376 amino acid recombinant protein consists of an N-terminal domain corresponding to the extracellular domain of HVEM and C-terminal portion corresponding to amino acid 102 to 330 of human IgG1. The protein has a predicted molecular mass of approximat

Price:

20 µg/$272; 100 µg/$352

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Mouse TNFRSF14 / CD270 / HVEM Protein (Recombinant Fc/His,C-terminus) (Met1-Gln206) - LS-G138530

Source:

HEK 293 Cells

Tag:

Fc/His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.4 kDa

Price:

100 µg/$600

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant DDK (Flag)-His, C-terminus) - LS-G142284

Source:

HEK 293 Cells

Tag:

DDK (Flag)-His, C-terminus

Molecular Weight:

19 kDa

Price:

20 µg/$1,107

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant His-T7) (aa41-209) - LS-G25387

Source:

E. coli

Tag:

His-T7

Molecular Weight:

21.8 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant GST) (Full Length) - LS-G31316

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

52.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant) - LS-G27259

Source:

Sf9 Cells

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

~45 kDa (SDS-PAGE)

Price:

50 µg/$262; 1 mg/$711

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Human TNFRSF14 / CD270 / HVEM Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76444

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.42 kDa

Price:

20 µg/$150

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant His, C-Terminal) (Leu39-Val202) - LS-G55736

Source:

Human

Tag:

His, C-Terminal

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

18.38kD

Price:

10 µg/$248; 50 µg/$299; 500 µg/$725; 1 mg/$1,067

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65877

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.1 kDa

Price:

20 µg/$1,107

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TNFRSF14 / CD270 / HVEM Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100138

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.42 kDa

Price:

100 µg/$494

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant) - LS-G350

Source:

High Five Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Price:

20 µg/$268; 100 µg/$349

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Mouse TNFRSF14 / CD270 / HVEM Protein (Recombinant Fc, C-terminus) - LS-G136775

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45.6 kDa

Price:

50 µg/$313; 10 µg/$259; 1 mg/$1,470; 500 µg/$1,025

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant Fc, C-terminus) (Leu39-Val202) - LS-G138750

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44.5 kDa

Price:

10 µg/$262; 50 µg/$317

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Monkey-Rhesus TNFRSF14 / CD270 / HVEM Protein (Recombinant Fc, C-terminus) (Pro37-Val203) - LS-G138784

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44.7 kDa

Price:

10 µg/$262; 50 µg/$317

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant mFc, C-terminus) (Pro37-Val202) - LS-G138836

Source:

Mammalian Cells

Tag:

mFc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44.1 kDa

Price:

10 µg/$262; 50 µg/$339

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Mouse TNFRSF14 / CD270 / HVEM Protein (Recombinant Fc, C-terminus) (Gln39-Val207) - LS-G138641

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45.6 kDa

Price:

10 µg/$248; 50 µg/$288

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant His,C-terminus) (Leu39-Val202) - LS-G138670

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

18.38 kDa

Price:

10 µg/$248; 50 µg/$299

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Mouse TNFRSF14 / CD270 / HVEM Protein (Recombinant Fc, C-terminus) (Gln39-Val207) - LS-G40048

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45.6kD

Price:

10 µg/$248; 50 µg/$288; 500 µg/$785; 1 mg/$1,203

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant) (Leu39-Val202) - LS-G55739

Source:

Human

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

44.5kD

Price:

50 µg/$321; 500 µg/$802; 1 mg/$1,113; 10 µg/$262

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Human TNFRSF14 / CD270 / HVEM Protein (Recombinant His, N-Terminal) - LS-G132859

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

22kDa

Price:

10 µg/$362; 50 µg/$902; 200 µg/$1,553; 100 µg/$1,325; 1 mg/$2,881; 500 µg/$2,369; 5 mg/$6,301; 2 mg/$3,361

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