TNFRSF11A / RANK

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

TNFRSF11A / RANK is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

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Products

Proteins (19)

Type

Over-Expression Lysate (2)

Recombinant (17)

Target

TNFRSF11A / RANK (19)

Publications

No (19)

Tag

6His, C-terminus (4)

6His, N-terminus (1)

Fc (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His,C-terminus (1)

His-T7 (2)

Human IgG1 Fc (2)

Myc-DDK (Flag) (2)

Species

Human (11)

Mouse (4)

Rat (3)

Source

293T Cells (1)

E. coli (7)

HEK 293 Cells (5)

Human Cells (3)

Mammalian Cells (2)

Wheat Germ Extract (1)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (10)

Biologically Active

Biologically active (3)

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Mouse TNFRSF11A / RANK Protein (Recombinant His, N-Terminal) (aa359-542) - LS-G14691

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

30.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human TNFRSF11A / RANK Protein (Recombinant Human IgG1 Fc) (aa29-213) - LS-G3880

Source:

HEK 293 Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

~55kDa (SDS-PAGE)

Price:

50 µg/$351

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Rat TNFRSF11A / RANK Protein (Recombinant His,C-terminus) (Met1-Pro213) - LS-G138525

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

21.5 kDa

Price:

100 µg/$502

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TNFRSF11A / RANK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117056

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.03 kDa

Price:

100 µg/$710

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Human TNFRSF11A / RANK Protein (Recombinant His) (aa28-202) - LS-G22405

Source:

E. coli

Tag:

His

Molecular Weight:

23.3 kD

Price:

100 µg/$420; 20 µg/$323; 1 mg/$1,355

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Human TNFRSF11A / RANK Protein (Recombinant 6His, N-terminus) (Ile30-Pro212) - LS-G26558

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

20 kDa

Price:

10 µg/$265; 50 µg/$315; 200 µg/$484

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Human TNFRSF11A / RANK Protein (Recombinant GST, N-terminus) (aa31-130) - LS-G60866

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TNFRSF11A / RANK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80271

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.03 kDa

Price:

20 µg/$215

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Rat TNFRSF11A / RANK Protein (Recombinant Fc) (Met1-Pro213) - LS-G98486

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

47.1 kDa

Price:

100 µg/$502

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Human TNFRSF11A / RANK Protein (Recombinant) (aa29-202) - LS-G5776

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

19.1 kDa

Price:

100 µg/$425; 500 µg/$789

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Human TNFRSF11A / RANK Protein (Recombinant) - LS-G333

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

19.3 kDa

Price:

20 µg/$268; 100 µg/$349

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Mouse TNFRSF11A / RANK Protein (Recombinant 6His, C-terminus) (Val31-Ser214) - LS-G139273

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

21.3 kDa

Price:

10 µg/$281; 50 µg/$389

Select

Human TNFRSF11A / RANK Protein (Recombinant) - LS-G137708

Source:

HEK 293 Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 191 amino acid recombinant protein has a predicted molecular mass of approximately 47.8 kD. The protein migrates at approximately 60 kD in DTT-reduced conditions and at approximately 120 kD in non-reduced conditions by SDS-PAGE. The predicted N-termin

Price:

25 µg/$306; 100 µg/$375

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Human TNFRSF11A / RANK Protein (Recombinant 6His, C-terminus) (Ile30-Pro212) - LS-G139147

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

21.1 kDa

Price:

10 µg/$277; 50 µg/$389

Select

Mouse TNFRSF11A / RANK Protein (Recombinant Human IgG1 Fc) (aa31-214) - LS-G3929

Source:

HEK 293 Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

~55kDa (SDS-PAGE)

Price:

50 µg/$379

Select

Human TNFRSF11A / RANK Protein (Recombinant 6His, C-terminus) (Ile30-Pro212) - LS-G40119

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

21.1kD

Price:

10 µg/$277; 50 µg/$395; 500 µg/$1,203; 1 mg/$1,627

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Mouse TNFRSF11A / RANK Protein (Recombinant 6His, C-terminus) (Val31-Ser214) - LS-G40348

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

21.3kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Human TNFRSF11A / RANK Protein (Recombinant His-T7) (aa330-615) - LS-G14696

Source:

E. coli

Tag:

His-T7

Molecular Weight:

33.8 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Rat TNFRSF11A / RANK Protein (Recombinant His-T7) (aa31-214) - LS-G14697

Source:

E. coli

Tag:

His-T7

Molecular Weight:

24.0 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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