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| Catalog Number | Size | Price |
|---|---|---|
| LS-G137708-25 | 25 µg (0.2 mg/ml) | $306 |
| LS-G137708-100 | 100 µg | $375 |
Human TNFRSF11A / RANK Protein (Recombinant) - LS-G137708
Human TNFRSF11A / RANK Protein (Recombinant) - LS-G137708
Description:
TNFRSF11A / RANK Protein LS-G137708 is a Recombinant Human TNFRSF11A / RANK produced in HEK 293 Cells. It is biologically active and is low in endotoxin; Less than 0.01 ng/µg (determined by LAL method). For Research Use Only
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206-374-1102
206-374-1102For Research Use Only
Overview
Description:
TNFRSF11A / RANK Protein LS-G137708 is a Recombinant Human TNFRSF11A / RANK produced in HEK 293 Cells. It is biologically active and is low in endotoxin; Less than 0.01 ng/µg (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
TNFRSF11A / RANK
Synonyms
TNFRSF11A | CD265 | CD265 antigen | ODFR | LOH18CR1 | OPTB7 | OSTS | PDB2 | RANK | Receptor activator of NF-KB | TRANCER | FEO | OFE
Species
Human
Modifications
Carrier-free
Conjugations
Unconjugated
Predicted Molecular Weight
The 191 amino acid recombinant protein has a predicted molecular mass of approximately 47.8 kD. The protein migrates at approximately 60 kD in DTT-reduced conditions and at approximately 120 kD in non-reduced conditions by SDS-PAGE. The predicted N-termin
Expression System
HEK 293 Cells
Source Species
Human
Purification
Greater than 95% by SDS-PAGE
Usage Summary
Stock solutions can also be prepared at 50 - 100 µg/mL in sterile buffer (PBS, HPBS, DPBS, or EBSS) containing carrier protein such as 0.2 - 1% BSA or HSA.
Bio-Activity
ED50 is equal to50 - 200 ng/mL, as determined by inhibition of osteoclast differentiation induced by RANKL (20 ng/mL) on RAW246.7 macrophages.
Endotoxin
Less than 0.01 ng/µg (determined by LAL method).
Presentation
0.22 µm filtered protein solution in PBS, pH 7.2
Storage
Store unopened at 2°C to 8°C for up to 1 month, at -20°C for up to 6 months, or at -70°C for up to 1 year. Store diluted at -20°C to -70°C. Avoid freeze/thaw cycles. For maximum results, quick spin vial prior to opening.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TNFRSF11A / RANK
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Inhibition
RANK inhibits osteoclast differentiation induced by human RANKL on RAW246.7 murine macrophages.
Inhibition
RANK inhibits osteoclast differentiation induced by human RANKL on RAW246.7 murine macrophages.
Inhibition
RANK inhibits osteoclast differentiation induced by human RANKL on RAW246.7 murine macrophages.
Inhibition
RANK inhibits osteoclast differentiation induced by human RANKL on RAW246.7 murine macrophages.
Popular TNFRSF11A / RANK Proteins
Source:
Human
Tag:
Human IgG1 Fc
Source:
E. coli
Tag:
His, N-Terminal
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/27/2024
Date Requested: 4/27/2024
