TFPI2 is a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.
|Gene Name:||tissue factor pathway inhibitor 2|
|Synonyms:||TFPI2, Placental protein 5, TFPI-2, PP5, REF1|
|Target Sequences:||NM_006528 NP_006519.1 P48307|
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