Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 610/620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

MAPK7 / ERK5

mitogen-activated protein kinase 7

ERK5, a MAPK type protein kinase, mediates growth factor stimulated cell proliferation and muscle cell differentiation. ERK5 differs from other MAP kinases in that it contains a unique loop-12 region within the protein kinase domain which is followed by an extensive C-terminal tail with sequences indicating that it may be targeted to the cytoskeleton. ERK5 is phosphorylated and activated by MEK5 in response to osmotic shock, growth factors and oxidant stress. Activated ERK5 phosphorylates myocyte enhancer factor 2 (MEF2), Sap1, NF-kappaB and p90 ribosomal S6 kinase (RSK/MAPKAPK1). ERK (-/-) mice are defective in blood-vessel and cardiac development. At least four alternatively spliced transcript variants of this gene encoding two distinct protein isoforms, 677 and 815 amino acids, have been identified. ERK5 has been shown to participate in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2.

Gene Name: mitogen-activated protein kinase 7
Family/Subfamily: Protein Kinase , MAPK
Synonyms: MAPK7, Big MAP kinase 1, BMK-1, Erk4, ERK5, MAPK 7, PRKM7, BMK1, BMK1 kinase, ERK-5, MAP kinase 7
Target Sequences: NM_002749 NP_002740.2 Q13164

☰ Filters
Antibodies (58)
Proteins (9)
Over-Expression Lysate (4)
Primary (58)
Recombinant (5)
MAPK7 / ERK5 (67)
Human (50)
Mouse (21)
Rat (11)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (2)
Pig (11)
Rabbit (3)
IHC (14)
IHC-P (4)
WB (56)
Flo (10)
ELISA (10)
IF (12)
IP (4)
Peptide-ELISA (1)
rabbit (42)
mouse (10)
sheep (6)
Product Group
IHCPlus (2)
IgG (25)
IgG1 (10)
monoclonal mc (10)
polyclonal pc (48)
OTI1A4 (2)
OTI1G1 (2)
OTI3H2 (2)
OTI4F9 (2)
OTI5B9 (2)
APC (2)
APC Conjugated (4)
Azide-free (2)
Biotin Conjugated (5)
Carrier-free (5)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (31)
aa185-419 (8)
aa560-793 (8)
aa776-805 (7)
C-Terminus (6)
aa213-224, pThr218/Tyr220 (5)
aa1-310 (1)
aa475-525 (1)
aa766-816 (1)
pThr218/Tyr220 (1)
No (67)
GST (1)
GST, N-terminus (1)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (6)
Mouse (1)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
MAPK7 / ERK5 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal (aa776-805) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
MAPK7 / ERK5 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
MAPK7 / ERK5 Sheep anti-Human Polyclonal (pThr218/Tyr220) Antibody
Human
WB
Unconjugated
200 µl/$854
MAPK7 / ERK5 Antibody - Immunohistochemistry of paraffin-embedded human esophageal cancer using MAPK7 antibody at dilution of 1:100 (400x lens).
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MAPK7 / ERK5 Antibody - Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal (aa475-525) Antibody
Human
IHC, IHC-P, IP
Unconjugated
50 µl/$460
MAPK7 / ERK5 Antibody - Anti-MAPK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK7.
Select
MAPK7 / ERK5 Mouse anti-Human Monoclonal (OTI3H2) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
MAPK7 / ERK5 Antibody - Anti-MAPK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK7.
Select
MAPK7 / ERK5 Mouse anti-Human Monoclonal (Carrier-free) (OTI3H2) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
MAPK7 / ERK5 Antibody - Anti-MAPK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK7.
Select
MAPK7 / ERK5 Mouse anti-Human Monoclonal (OTI4F9) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
MAPK7 / ERK5 Antibody - Anti-MAPK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK7.
Select
MAPK7 / ERK5 Mouse anti-Human Monoclonal (Carrier-free) (OTI4F9) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
MAPK7 / ERK5 Antibody - Anti-MAPK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK7.
Select
MAPK7 / ERK5 Mouse anti-Human Monoclonal (OTI5B9) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
MAPK7 / ERK5 Antibody - Anti-MAPK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK7.
Select
MAPK7 / ERK5 Mouse anti-Human Monoclonal (Carrier-free) (OTI5B9) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
MAPK7 / ERK5 Antibody - Anti-MAPK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK7.
Select
MAPK7 / ERK5 Mouse anti-Human Monoclonal (OTI1G1) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
MAPK7 / ERK5 Antibody - Anti-MAPK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK7.
Select
MAPK7 / ERK5 Mouse anti-Human Monoclonal (Carrier-free) (OTI1G1) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
MAPK7 / ERK5 Antibody - Anti-MAPK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK7.
Select
MAPK7 / ERK5 Mouse anti-Human Monoclonal (OTI1A4) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
MAPK7 / ERK5 Antibody - Anti-MAPK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK7.
Select
MAPK7 / ERK5 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A4) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
MAPK7 / ERK5 Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using MAPK7 Polyclonal Antibody at dilution of 1:35.
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal (aa776-805) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal (aa776-805) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal (aa776-805) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal (aa776-805) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal (aa776-805) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal (aa776-805) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
MAPK7 / ERK5 Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal (aa1-310) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
MAPK7 / ERK5 Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
MAPK7 / ERK5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Viewing 1-25 of 67 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).