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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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SYNCAM / CADM1

cell adhesion molecule 1

Mediates homophilic cell-cell adhesion in a Ca2+-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly By similarity. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.

Gene Name: cell adhesion molecule 1
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: CADM1, BL2, Cell adhesion molecule 1, IGSF4, Necl-2, IGSF4A, RA175, SYNCAM, SynCAM1, STSLC-1, TSLC1/Nectin-like 2/IGSF4, NECL2, Nectin-like protein 2, TSLC-1, TSLC1, Nectin-like 2, SgIGSF, ST17, Truncated CADM1 protein
Target Sequences: NM_014333 NP_055148.3 Q9BY67

Publications (1)

1
SMAGP, a new small trans-membrane glycoprotein altered in cancer. Tarb NG, Rio MC, Weidle UH. Oncogene. 2004 23:3395-403. [PubMed:15021913]

☰ Filters
Antibodies (51)
Primary (51)
SYNCAM / CADM1 (51)
Human (50)
Mouse (29)
Rat (14)
Bat (1)
Bovine (2)
Dog (1)
Guinea pig (1)
Hamster (1)
Horse (1)
Monkey (1)
Rabbit (1)
IHC (14)
IHC-P (5)
WB (47)
Flo (1)
ELISA (15)
ICC (7)
IF (3)
Peptide-ELISA (3)
rabbit (47)
goat (2)
rat (2)
Product Group
PathPlus Neuro (2)
IgG (29)
IgG1,k (2)
monoclonal mc (2)
polyclonal pc (49)
41N3D3 (1)
AP Conjugated (3)
APC (1)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (4)
Unconjugated (26)
aa27-292 (8)
aa66-94 (8)
C-Terminus (2)
370-450 aa, C-terminal (1)
Internal Region (1)
aa125-137 (1)
aa150-200 (1)
aa393-442 (1)
aa45-340 (1)
aa45-344 (1)
aa73-92 (1)
No (51)
SYNCAM / CADM1 Antibody - Anti-CADM1 antibody IHC of human colon, lamina propria macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
Select
Neuroscience
SYNCAM / CADM1 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$425
SYNCAM / CADM1 Antibody - Anti-CADM1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Select
Neuroscience
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa393-442) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$425
SYNCAM / CADM1 Antibody - CADM1 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lung carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa66-94) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$325
SYNCAM / CADM1 Antibody - WB of SYNCAM / CADM1 antibody. All lanes: Anti-CADM1 at 0.5ug/ml. Lane 1: A549 Whole Cell Lysate at 40ug. Lane 2: JURKAT Whole Cell Lysate at 40ug. Lane 3: RAJI Whole Cell Lysate at 40ug. Lane 4: HELA Whole Cell Lysate at 40ug. Predicted bind size: 60KD. Observed bind size: 60KD.
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa73-92) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$325
SYNCAM / CADM1 Antibody - Western blot of TSLC1 antibody
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SYNCAM / CADM1 Rabbit anti-Human Polyclonal (370-450 aa, C-terminal) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µl/$235; 100 µl/$265; 200 µl/$335
SYNCAM / CADM1 Antibody - CADM1 antibody (1 ug/ml) staining of Mouse fetal Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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SYNCAM / CADM1 Goat anti-Human Polyclonal (aa125-137) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$405
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$325
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa66-94) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$590
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa66-94) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$740
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa66-94) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$740
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa66-94) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$740
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa66-94) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$740
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa66-94) (AP) Antibody
Mouse, Human
ELISA, IHC, WB
AP Conjugated
200 µl/$740
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa66-94) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$740
SYNCAM / CADM1 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µl/$325; 200 µl/$375
SYNCAM / CADM1 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using antibody at 1:100 dilution.
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (aa45-344) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$285; 100 µl/$385
Select
SYNCAM / CADM1 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$335
SYNCAM / CADM1 Antibody - Western blot analysis of extracts of various cell lines, using CADM1 antibody.
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$215; 50 µl/$235; 100 µl/$315; 200 µl/$425
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, WB
Unconjugated
100 µg/$665
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Rat, Human
ICC, WB
Biotin Conjugated
100 µl/$845
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Rat, Human
ICC, WB
FITC Conjugated
100 µl/$845
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal (AP) Antibody
Mouse, Rat, Human
ICC, WB
AP Conjugated
100 µl/$845
SYNCAM / CADM1 Antibody - Western blot of extracts of mouse liver cell lines, using CADM1 antibody.
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$385
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$405
SYNCAM / CADM1 Antibody - Western blot analysis of extracts from HeLa cells, using CADM1 antibody.
Select
SYNCAM / CADM1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$305
Viewing 1-25 of 51 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).