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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
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SYNCAM / CADM1

cell adhesion molecule 1

Mediates homophilic cell-cell adhesion in a Ca2+-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly By similarity. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.

Gene Name: cell adhesion molecule 1
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: CADM1, BL2, Cell adhesion molecule 1, IGSF4, Necl-2, IGSF4A, RA175, SYNCAM, SynCAM1, STSLC-1, TSLC1/Nectin-like 2/IGSF4, NECL2, Nectin-like protein 2, TSLC-1, TSLC1, Nectin-like 2, SgIGSF, ST17, Truncated CADM1 protein
Target Sequences: NM_014333 NP_055148.3 Q9BY67

Publications (1)

1
SMAGP, a new small trans-membrane glycoprotein altered in cancer. Tarb NG, Rio MC, Weidle UH. Oncogene. 2004 23:3395-403. [PubMed:15021913]

Viewing 1-25 of 50 items
SYNCAM / CADM1 Antibody - Anti-CADM1 antibody IHC of human colon, lamina propria macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
Select
Neuroscience
Rabbit Polyclonal to Rat SYNCAM / CADM1
Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl   $425.00
SYNCAM / CADM1 Antibody - Anti-CADM1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Select
Neuroscience
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
SYNCAM / CADM1 Antibody - CADM1 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lung carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
Rabbit Polyclonal to Human SYNCAM / CADM1
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
SYNCAM / CADM1 Antibody - WB of SYNCAM / CADM1 antibody. All lanes: Anti-CADM1 at 0.5ug/ml. Lane 1: A549 Whole Cell Lysate at 40ug. Lane 2: JURKAT Whole Cell Lysate at 40ug. Lane 3: RAJI Whole Cell Lysate at 40ug. Lane 4: HELA Whole Cell Lysate at 40ug. Predicted bind size: 60KD. Observed bind size: 60KD.
Select
Rabbit Polyclonal to Human SYNCAM / CADM1
Mouse, Rat, Human
WB
Unconjugated
100µg   200µl   0.5mg/ml   $325.00
SYNCAM / CADM1 Antibody - Western blot of TSLC1 antibody
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
ELISA, IF, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
SYNCAM / CADM1 Antibody - CADM1 antibody (1 ug/ml) staining of Mouse fetal Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Goat Polyclonal to Human SYNCAM / CADM1
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100µg   0.5mg/ml   $405.00
Select
Rabbit Polyclonal to Human SYNCAM / CADM1
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $325.00
SYNCAM / CADM1 Antibody
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
SYNCAM / CADM1 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using antibody at 1:100 dilution.
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Human
ELISA, IHC, IHC-P
Unconjugated
50µl   $285.00; 100µl   $385.00
Select
Rabbit Polyclonal (IgG) to Mouse SYNCAM / CADM1
Mouse
ELISA, WB
Unconjugated
100µg   $335.00
SYNCAM / CADM1 Antibody - Western blot of extracts of mouse liver cell lines, using CADM1 antibody.
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Rabbit Polyclonal to Human SYNCAM / CADM1
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl   $385.00
SYNCAM / CADM1 Antibody - Western blot analysis of extracts of various cell lines, using CADM1 antibody.
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Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Human
IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
Select
Rabbit Polyclonal to Human SYNCAM / CADM1
Mouse, Rat, Human
ICC, WB
Unconjugated
100µg   $650.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Rat, Human
ICC, WB
Biotin Conjugated
100µl   $830.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Rat, Human
ICC, WB
FITC Conjugated
100µl   $830.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Rat, Human
ICC, WB
AP Conjugated
100µl   $830.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Mouse, Rat, Human
ICC, WB
APC Conjugated
100µl   $830.00
Select
Rabbit Polyclonal (IgG) to Human SYNCAM / CADM1
Human
ELISA, WB
Unconjugated
100µg   $405.00

Viewing 1-25 of 50 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).