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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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SPRY2 / Sprouty 2

sprouty homolog 2 (Drosophila)

SPRY2 / Sprouty 2 is a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.

Gene Name: sprouty homolog 2 (Drosophila)
Synonyms: SPRY2, HSPRY2, Protein sprouty homolog 2, Sprouty homolog 2 (Drosophila), Sprouty 2, Spry-2, Sprouty (Drosophila) homolog 2
Target Sequences: NM_005842 NP_005833.1 O43597

Publications (1)

1
Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2. Zhang C, Chaturvedi D, Jaggar L, Magnuson D, Lee JM, Patel TB. Arteriosclerosis, thrombosis, and vascular biology. 2005 25:533-8. [PubMed:15653567]


SPRY2 / Sprouty 2 Antibody - Anti-SPRY2 / Sprouty 2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $485.00
SPRY2 / Sprouty 2 Antibody - Anti-SPRY2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human SPRY2 / Sprouty 2
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
SPRY2 / Sprouty 2 Antibody - Anti-SPRY2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human SPRY2 / Sprouty 2
Rabbit, Mouse, Dog, Bovine, Pig, Horse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
SPRY2 / Sprouty 2 Antibody - Anti-SPRY2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human SPRY2 / Sprouty 2
Rabbit, Mouse, Dog, Bovine, Pig, Horse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100µl   1mg/ml   $385.00
SPRY2 / Sprouty 2 Antibody - Anti-SPRY2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human SPRY2 / Sprouty 2
Rabbit, Mouse, Dog, Bovine, Pig, Horse, Rat, Hamster, Chimpanzee, Orangutan, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100µl   1mg/ml   $385.00
SPRY2 / Sprouty 2 Antibody - Immunoperoxidase of monoclonal antibody to SPRY2 on formalin-fixed paraffin-embedded human lymphoma. [antibody concentration 3 ug/ml].
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Mouse Monoclonal [clone 1E10] (IgG) to Human SPRY2 / Sprouty 2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100µg   $365.00
SPRY2 / Sprouty 2 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue using SPRY2 Antibody at dilution of 1:100
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Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µg   $285.00; 100µg   4mg/ml   $385.00
SPRY2 / Sprouty 2 Antibody - Western blot of recombinant SPRY2 / Sprouty 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Mouse SPRY2 / Sprouty 2
Mouse
WB
Unconjugated
100µl   0.5mg/ml   $275.00; 200µl   0.5mg/ml   $315.00; 500µl   0.5mg/ml   $475.00; 1ml   0.5mg/ml   $590.00
SPRY2 / Sprouty 2 Antibody - Immunohistochemistry of rabbit anti-Sprouty-2 antibody. Tissue: kidney. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: Anti-sprouty 2 at 10 µg/mL for 1 h at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Staining: Sprouty-2 as precipitated red signal with hematoxylin purple nuclear counterstain.
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Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Human
ELISA, IF, IHC, WB
Unconjugated
25µl   1.04mg/ml   $235.00
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $355.00
SPRY2 / Sprouty 2 Antibody - Western blot of recombinant SPRY2 / Sprouty 2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human SPRY2 / Sprouty 2
Human
ICC, IP, WB
Unconjugated
20µl   0.5mg/ml   $205.00; 100µl   0.5mg/ml   $265.00; 200µl   0.5mg/ml   $315.00; 1ml   0.5mg/ml   $575.00
Select
Rabbit Polyclonal to Human SPRY2 / Sprouty 2
Human
ELISA, IP, WB
Unconjugated
100µg   $755.00
Select
Rabbit Polyclonal to Human SPRY2 / Sprouty 2
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl   $385.00
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Human
ELISA, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal to Human SPRY2 / Sprouty 2
Mouse, Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Dog, Rat, Hamster, Pig, Human
WB
Unconjugated
200µg   $620.00
SPRY2 / Sprouty 2 Antibody - HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Dog, Rat, Hamster, Pig, Human
WB
Unconjugated
100µl   0.5mg/ml   $385.00
SPRY2 / Sprouty 2 Antibody - Western blot analysis of extracts of A375 cells.
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Human
WB
Unconjugated
100µl   $295.00; 200µl   $385.00
SPRY2 / Sprouty 2 Antibody - Western blot analysis of extracts of various cell lines, using SPRY2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
Rabbit Polyclonal (IgG) to Human SPRY2 / Sprouty 2
Mouse, Human
WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $295.00; 200µl   $385.00
Viewing 1-25 of 63 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).