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Mediates the Na+-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver.
Gene Name: | solute carrier organic anion transporter family, member 1B1 |
Family/Subfamily: | Transporter , Organic anion transporter |
Synonyms: | SLCO1B1, OATP-2, Oatp2, OATP-C, OATPC, ORGANIC ANION TRANSPORTER C, RLST-1, OATP1B1, SLC21A6 |
Target Sequences: | NM_006446 NP_006437.3 Q9Y6L6 |
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