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SFTPA1 / Surfactant Protein A

surfactant protein A1

SFTPA1 / Surfactant Protein A is a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants.

Gene Name: surfactant protein A1
Synonyms: SFTPA1, Alveolar proteinosis protein, COLEC4, Collectin-4, PSP-A, PSPA, SFTP1, SFTPA, SFTPA1B, SPA1, SP-A, SP-A1, SPA, Surfactant Protein A, Surfactant protein A1, Surfactant protein A1B, Surfactant A
Target Sequences: NM_005411 NP_005402.3 Q8IWL2

Publications (2)

1
Disruption of the structural and functional features of surfactant protein A by acrolein in cigarette smoke. Takamiya R, Uchida K, Shibata T, Maeno T, Kato M, Yamaguchi Y, Ariki S, Hasegawa Y, Saito A, Miwa S, Takahashi H, Akaike T, Kuroki Y, Takahashi M. Scientific reports. 2017 7:8304. (WB; Mouse) [Full Text Article] [PubMed:28814727] [PMC:PMC5559459] Related Antibodies: LS-C312616.
2
Functional roles of C/EBPα and SUMO‑modification in lung development. Chen YD, Liu JY, Lu YM, Zhu HT, Tang W, Wang QX, Lu HY. International journal of molecular medicine. 2017 40:1037-1046. (WB; Human) [Full Text Article] [PubMed:28902364] [PMC:PMC5593452]

☰ Filters
Products
Proteins (14)
Over-Expression Lysate (8)
Recombinant (6)
SFTPA1 / Surfactant Protein A (14)
No (14)
10His-B2M, N-terminus + Myc, C-terminus (1)
GST (1)
His, N-Terminal (1)
His-GST (1)
Myc-DDK (Flag) (10)
Human (8)
Mouse (1)
Rat (1)
293T Cells (4)
E. coli (3)
HEK 293 Cells (6)
Wheat Germ Extract (1)
Purified (2)
SFTPA1 / Surfactant Protein A Protein - Recombinant Surfactant Associated Protein A By SDS-PAGE
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E. coli
His, N-Terminal
27.9 kDa
50 µg/$442; 10 µg/$281; 200 µg/$882; 100 µg/$705; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
SFTPA1 / Surfactant Protein A Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His-B2M, N-terminus + Myc, C-terminus
100 µg/$1,128; 20 µg/$721
SFTPA1 / Surfactant Protein A Protein - Recombinant Surfactant Associated Protein A By SDS-PAGE
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E. coli
His-GST
56.6 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
SFTPA1 / Surfactant Protein A Protein - Purified recombinant protein SFTPA1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
26.1 kDa
20 µg/$1,107
SFTPA1 / Surfactant Protein A Protein - Purified recombinant protein SFTPA1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
21.5 kDa
20 µg/$1,107
SFTPA1 / Surfactant Protein A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
26.1 kDa
20 µg/$150
SFTPA1 / Surfactant Protein A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
21.5 kDa
20 µg/$150
SFTPA1 / Surfactant Protein A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
26.1 kDa
20 µg/$150
SFTPA1 / Surfactant Protein A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
26.1 kDa
20 µg/$150
SFTPA1 / Surfactant Protein A Protein - 12.5% SDS-PAGE of human SFTPA1 stained with Coomassie Blue
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Wheat Germ Extract
GST
38.61 kDa
10 µg/$479; 25 µg/$670
SFTPA1 / Surfactant Protein A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21.5 kDa
100 µg/$494
SFTPA1 / Surfactant Protein A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.1 kDa
100 µg/$494
SFTPA1 / Surfactant Protein A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.1 kDa
100 µg/$494
SFTPA1 / Surfactant Protein A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
26.1 kDa
100 µg/$494
Viewing 1-14 of 14 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).