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SDC1 / Syndecan 1 / CD138

syndecan 1

SDC1 / Syndecan 1 / CD138 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Gene Name: syndecan 1
Synonyms: SDC1, CD138 antigen, SDC, SYND1, Syndecan, Syndecan 1, Syndecan-1, CD138, Syndecan proteoglycan 1
Target Sequences: NM_002997 NP_002988.3 P18827

Publications (2)

1
Increased CXCR3 Expression of Infiltrating Plasma Cells in Hunner Type Interstitial Cystitis. Akiyama Y, Morikawa T, Maeda D, Shintani Y, Niimi A, Nomiya A, Nakayama A, Igawa Y, Fukayama M, Homma Y. Scientific reports. 2016 6:28652. (IHC-P; Human) [Full Text Article] [PubMed:27339056] [PMC:PMC4919639]
2
Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores the angiogenic homeostasis and suppresses tumor progression. Antonio G Solimando, Matteo C Da Vià, Patrizia Leone, Paola Borrelli, Giorgio A Croci, Paula Tabares, Andreas Brandl, Giuseppe Di Lernia, Francesco P Bianchi, Silvio Tafuri, Torsten Steinbrunn, Alessandra Balduini, Assunta Melaccio, Simona De Summa, Antonella Argentiero, Hilka Rauert-Wunderlich, Maria A Frassanito, Paolo Ditonno, Erik Henke, Wolfram Klapper, Roberto Ria, Carolina Terragna, Leo Rasche, Andreas Rosenwald, Martin K Kortüm, Michele Cavo, Domenico Ribatti, Vito Racanelli, Hermann Ein. Haematologica. 2020 April; [Full Text Article] [PubMed:32354870] [PMC:PMC8252928] Related Antibodies: LS-B9360.

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Antibodies (117)
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SDC1 / Syndecan 1 / CD138 (117)
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SDC1 / Syndecan 1 / CD138 Antibody - Anti-SDC1 / Syndecan 1 / CD138 antibody IHC staining of human tonsil, squamous epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Cancer Pathology
Cancer
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (B-A38) Antibody
Human
Flo, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.05 mg/$460
SDC1 / Syndecan 1 / CD138 Antibody - Anti-SDC1 / Syndecan 1 / CD138 antibody IHC staining of human tonsil, squamous epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (RPE) (B-A38) Antibody
Human
Flo
RPE Conjugated
100 Tests/$456
SDC1 / Syndecan 1 / CD138 Antibody - Anti-Syndecan / CD138 antibody IHC of human skin, epidermis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (MI15) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
250 µl/$460
SDC1 / Syndecan 1 / CD138 Antibody - Anti-CD138 antibody IHC of human placenta, trophoblast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:250.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$485
SDC1 / Syndecan 1 / CD138 Antibody - IHC of paraffin-embedded ovarian cancer tissues using SDC1 mouse monoclonal antibody with DAB staining.
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SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (aa28-171) (1A3H4) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
0.1 mg/$426
SDC1 / Syndecan 1 / CD138 Antibody - Anti-SDC1 / Syndecan 1 / CD138 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (aa210-238) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
0.05 ml/$460
SDC1 / Syndecan 1 / CD138 Antibody - Anti-CD138 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IHC-P
Unconjugated
50 µg/$460
SDC1 / Syndecan 1 / CD138 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (Concentrated) Antibody
Human
ELISA, IHC-P
Unconjugated, Concentrated
0.05 ml/$460
SDC1 / Syndecan 1 / CD138 Antibody - Anti-Syndecan / CD138 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
SDC1 / Syndecan 1 / CD138 Antibody - Anti-Syndecan / CD138 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Hamster, Human
IHC, IHC-P
Unconjugated
50 µg/$485
SDC1 / Syndecan 1 / CD138 Antibody - Surface staining of human peripheral blood with anti-human CD138 (MI15) purified / GAM-APC.
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SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (MI15) Antibody
Rat, Non-Human Primates, Human
Flo, IHC-P, IP, WB
Unconjugated
0.1 mg/$306
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SDC1 / Syndecan 1 / CD138 Rat anti-Human Monoclonal (aa18-251) Antibody
Human
ELISA, Flo, IHC
Unconjugated
100 µg/$814
SDC1 / Syndecan 1 / CD138 Antibody - Western blot of the lysates from HepG2 cells using SDC1 antibody.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa83-132) Antibody
Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$318; 100 µl/$378
SDC1 / Syndecan 1 / CD138 Antibody - Flow cytometric analysis of Human SDC1(CD138) expression on RPMI8226 cells. Cells were stained with PE-conjugated anti-Human SDC1(CD138). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (PE) (017) Antibody
Human
Flo
PE Conjugated
25 Tests/$249; 100 Tests/$343
SDC1 / Syndecan 1 / CD138 Antibody - Immunochemical staining of human SDC1 in human kidney with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (Preservative Free) (160) Antibody
Human
IHC-P
Unconjugated, Preservative Free
50 µl/$290; 100 µl/$350
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SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
500 µl/$588
SDC1 / Syndecan 1 / CD138 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa23-254) Antibody
Human
ELISA, IF, IHC-P
Unconjugated
50 µg/$460
SDC1 / Syndecan 1 / CD138 Antibody - Flow cytometric analysis of Human SDC1(CD138) expression on RPMI8226 cells. Cells were stained with purified anti-Human SDC1(CD138), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (Preservative Free) (017) Antibody
Human
ELISA, Flo
Unconjugated, Preservative Free
50 µl/$290; 100 µl/$350
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SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (Biotin) (531CT15.4.1;531CT15.1.4) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$828
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (Preservative Free) (001) Antibody
Human
ELISA
Unconjugated, Preservative Free
50 µl/$290; 100 µl/$350
SDC1 / Syndecan 1 / CD138 Antibody - Western blot of CD138 Antibody (C-term K281) in HepG2 cell line lysates (35 ug/lane). CD138 (arrow) was detected using the purified antibody.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa266-295) Antibody
Human
WB
Unconjugated
400 µl/$376
SDC1 / Syndecan 1 / CD138 Antibody - Syndecan-1 antibody Western blot. All lanes: Anti Syndecan-1 at 0.5 ug/ml. Lane 1: HT1080 Whole Cell Lysate at 40 ug. Lane 2: MCF-7 Whole Cell Lysate at 40 ug. Lane 3: 293T Whole Cell Lysate at 40 ug. Lane 4: HEPG2 Whole Cell Lysate at 40 ug. Lane 5: HELA Whole Cell Lysate at 40 ug. Predicted band size: 50 kD. Observed band size: 50 kD.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa218-251) Antibody
Human
WB
Unconjugated
100 µg/$421
SDC1 / Syndecan 1 / CD138 Antibody - Flow cytometric analysis of Human SDC1(CD138) expression on RPMI8226 cells. Cells were stained with FITC-conjugated anti-Human SDC1(CD138). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (FITC) (017) Antibody
Human
Flo
FITC Conjugated
25 Tests/$238; 100 Tests/$306
SDC1 / Syndecan 1 / CD138 Antibody - Flow cytometric analysis of Human SDC1(CD138) expression on RPMI8226 cells. Cells were stained with APC-conjugated anti-Human SDC1(CD138). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
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SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (APC) (017) Antibody
Human
Flo
APC Conjugated
25 Tests/$249; 100 Tests/$343
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SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr, IHC-P
Unconjugated
2 ml/$868
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).