Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

RNF7

ring finger protein 7

Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.

Gene Name: ring finger protein 7
Synonyms: RNF7, CKII beta-binding protein 1, CKBBP1, RING-box protein 2, Rbx2, Regulator of cullins 2, Ring finger protein 7, ROC2, Zinc RING finger protein SAG
Target Sequences: NM_014245 NP_055060.1 Q9UBF6

Publications (3)

1
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Kamura T, Koepp DM, Conrad MN, Skowyra D, Moreland RJ, Iliopoulos O, Lane WS, Kaelin WG, Elledge SJ, Conaway RC, Harper JW, Conaway JW. Science (New York, N.Y.). 1999 284:657-61. [PubMed:10213691] Related Antibodies: LS-C19102.
2
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Ohta T, Michel JJ, Schottelius AJ, Xiong Y. Molecular cell. 1999 3:535-41. [PubMed:10230407] Related Antibodies: LS-C19102.
3
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Seol JH, Feldman RM, Zachariae W, Shevchenko A, Correll CC, Lyapina S, Chi Y, Galova M, Claypool J, Sandmeyer S, Nasmyth K, Deshaies RJ, Shevchenko A, Deshaies RJ. Genes & development. 1999 13:1614-26. [PubMed:10385629] [PMC:PMC316801] Related Antibodies: LS-C19102.

☰ Filters
Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
RNF7 (7)
No (7)
GST (2)
His (2)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purified (2)
RNF7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
12.5 kDa
20 µg/$150
RNF7 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
RNF7 Protein
Select
Yeast
His
14.5 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Select
E. coli
GST
39.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RNF7 Protein - 12.5% SDS-PAGE of human RNF7 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
38.17 kDa
10 µg/$479; 25 µg/$670
RNF7 Protein - Purified recombinant protein RNF7 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
12.5 kDa
20 µg/$1,107
RNF7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
12.5 kDa
100 µg/$494
Viewing 1-7 of 7 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).