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PXN / Paxillin

paxillin

PXN / Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).

Gene Name: paxillin
Synonyms: PXN, Paxillin
Target Sequences: NM_002859 NP_002850.2 P49023

Publications (3)

1
RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility. Yao H, Dashner EJ, van Golen CM, van Golen KL. Oncogene. 2006 25:2285-96. [PubMed:16314838]
2
GIT1 utilizes a focal adhesion targeting-homology domain to bind paxillin. Schmalzigaug R, Garron ML, Roseman JT, Xing Y, Davidson CE, Arold ST, Premont RT. Cellular signalling. 2007 19:1733-44. (ICC, IP) [PubMed:17467235] [PMC:PMC2025689]
3
Podosomes are present in a postsynaptic apparatus and participate in its maturation. Proszynski TJ, Gingras J, Valdez G, Krzewski K, Sanes JR. Proceedings of the National Academy of Sciences of the United States of America. 2009 106:18373-8. [PubMed:19822767] [PMC:PMC2775295]

☰ Filters
Products
Antibodies (128)
Primary (128)
PXN / Paxillin (128)
Human (124)
Mouse (63)
Rat (53)
Bat (1)
Bovine (11)
Chicken (17)
Chimpanzee (3)
Dog (2)
Gibbon (3)
Guinea pig (1)
Horse (3)
Monkey (8)
Pig (3)
Rabbit (3)
Sheep (1)
Zebrafish (1)
IHC (27)
IHC-Fr (1)
IHC-P (8)
WB (123)
ELISA (31)
ICC (13)
IF (7)
IP (13)
Peptide-ELISA (11)
rabbit (99)
mouse (28)
sheep (1)
IgG (49)
IgG1 (22)
IgG1,k (2)
IgG2a (3)
IgG2b (1)
monoclonal mc (26)
polyclonal pc (100)
recombinant monoclonal rmc (2)
1D4B (1)
LD2 sAB (1)
LD4 sAB (1)
OTI1H10 (2)
OTI2B8 (2)
OTI6B7 (2)
OTI6G9 (2)
OTI8C12 (2)
PAX-14 (3)
APC (3)
APC Conjugated (5)
Azide-free (1)
Biotin Conjugated (7)
Carrier-free (5)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (7)
HRP Conjugated (7)
Magnetic beads Conjugated (1)
PE Conjugated (5)
Preservative Free (1)
Sepharose Conjugated (1)
Unconjugated (89)
pTyr118 (10)
pTyr31 (9)
aa201-461 (8)
aa327-568 (8)
aa347-578 (8)
Tyr118 (7)
C-Terminus (4)
aa111-160 (4)
aa49-98 (4)
pSer178 (3)
pTyr88 (3)
120-200 aa (2)
Internal (2)
N-Terminus (2)
aa1-50 (2)
aa59-274 (2)
10-90 aa (1)
210-290 aa (1)
50-130 aa (1)
Gln82 (1)
Leu25 (1)
Ser178 (1)
aa123-172 (1)
aa144-193 (1)
aa15-64 (1)
aa217-266 (1)
aa238-287 (1)
aa33-82 (1)
aa456-472 (1)
p118 (1)
p178 (1)
p272 (1)
p31 (1)
pSer126 (1)
pSer17 (1)
pSer272 (1)
No (128)
PXN / Paxillin Antibody - Immunohistochemical analysis of Paxillin staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PXN / Paxillin Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
PXN / Paxillin Antibody - Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with PXN Antibody (Y118) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PXN / Paxillin Antibody - Western blot of extracts from HT-29, using Paxillin (Phospho-Ser178) Antibody.
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PXN / Paxillin Rabbit anti-Human Polyclonal (pSer178) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
PXN / Paxillin Antibody - Immunohistochemical analysis of Paxillin staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP-conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PXN / Paxillin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
PXN / Paxillin Antibody - PXN / Paxillin antibody. IHC(P): Human Lung Cancer Tissue.
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PXN / Paxillin Rabbit anti-Human Polyclonal (aa456-472) Antibody
Chicken, Sheep, Bovine, Rat, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Human, Monkey
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
PXN / Paxillin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
Select
PXN / Paxillin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
Select
PXN / Paxillin Mouse anti-Chicken Monoclonal Antibody
Chicken, Mouse, Dog, Rat, Human
ELISA, ICC, IHC, IP, WB
Unconjugated
100 µg/$1,022
PXN / Paxillin Antibody - IHC of Paxillin (L25) pAb in paraffin-embedded human breast carcinoma tissue.
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PXN / Paxillin Rabbit anti-Human Polyclonal (Leu25) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
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PXN / Paxillin Mouse anti-Human Monoclonal Antibody
Chicken, Bovine, Mouse, Rat, Human
ELISA, ICC, IP, WB
Unconjugated
250 µg/$854
PXN / Paxillin Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Paxillin Antibody. The picture on the right is blocked with the synthesized peptide.
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PXN / Paxillin Rabbit anti-Human Polyclonal (aa15-64) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
PXN / Paxillin Rabbit anti-Human Polyclonal (pTyr118) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µl/$689
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PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
PXN / Paxillin Rabbit anti-Human Polyclonal (Tyr118) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PXN / Paxillin Antibody - Western blot of Phospho-Paxillin (Y31) antibody
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PXN / Paxillin Rabbit anti-Human Polyclonal (10-90 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PXN / Paxillin Antibody - Western blot of Phospho-Paxillin (Y88) antibody
Select
PXN / Paxillin Rabbit anti-Human Polyclonal (pTyr88) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PXN / Paxillin Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Paxillin (Ab-118) antibody.
Select
PXN / Paxillin Rabbit anti-Human Polyclonal (p118) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PXN / Paxillin Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Paxillin (Ab-31) antibody.
Select
PXN / Paxillin Rabbit anti-Human Polyclonal (p31) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PXN / Paxillin Antibody - Detection of Human Paxillin by Immunohistochemistry. Sample: FFPE section of human non-small cell lung cancer. Antibody: Affinity purified rabbit anti-Paxillin used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
Select
PXN / Paxillin Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
PXN / Paxillin Antibody - Immunohistochemical analysis of Paxillin (pY31) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
PXN / Paxillin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Pig, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
Select
PXN / Paxillin Mouse anti-Human Monoclonal (aa59-274) Antibody
Human
ICC, WB
Unconjugated
100 µg/$884
Select
PXN / Paxillin Mouse anti-Human Monoclonal (pTyr31) (1D4B) Antibody
Human
ICC, WB
Unconjugated
100 µg/$872
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).