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PODXL / Podocalyxin

podocalyxin-like

Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.

Gene Name: podocalyxin-like
Synonyms: PODXL, GCTM-2 antigen, gp200, PCLP, PCLP-1, PCLP1, Podocalyxin-like protein 1, Podocalyxin, Podocalyxin-like, TRA-1-60, TRA-1-81
Target Sequences: NM_005397 NP_005388.2 O00592

☰ Filters
Products
Antibodies (88)
Primary (88)
PODXL / Podocalyxin (88)
Human (72)
Mouse (19)
Rat (17)
Chimpanzee (3)
Gibbon (3)
Hamster (1)
Horse (1)
Monkey (4)
Rabbit (9)
IHC (35)
IHC-P (23)
WB (69)
Flo (20)
ELISA (21)
ICC (1)
IF (11)
IP (4)
Peptide-ELISA (1)
rabbit (56)
mouse (31)
goat (1)
Product Group
IHCPlus (1)
PathPlus Cancer (1)
PathPlus Cancer Pathology (1)
IgG (24)
IgG1 (17)
IgG1,k (1)
IgG2a (5)
IgG2b (1)
IgM (7)
monoclonal mc (31)
polyclonal pc (57)
2A4 (3)
3D3 (3)
4D2G7 (1)
4F10 (3)
4H11 (1)
53D11 (3)
5D4 (2)
5F5 (2)
OTI2C6 (2)
OTI8D6 (2)
OTI9C2 (2)
PODXL/2185 (2)
SPM487 (1)
APC (3)
APC Conjugated (4)
Azide-free (4)
Biotin Conjugated (8)
BSA-free (4)
Carrier-free (3)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (8)
HRP Conjugated (7)
PE Conjugated (6)
Ready-to-Use (3)
Unconjugated (46)
Extracellular Domain (10)
aa153-386 (8)
aa171-404 (8)
aa220-463 (8)
aa410-439 (8)
aa32-461 (6)
Internal (4)
aa131-180 (4)
aa301-350 (4)
C-Terminus (1)
aa100-200 (1)
aa543-557 (1)
No (88)
PODXL / Podocalyxin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
PODXL / Podocalyxin Mouse anti-Human Monoclonal (53D11) Antibody
Human
Flo, IHC, IHC-P
Unconjugated
50 µg/$460
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) Antibody
Human
Flo, ICC, WB
Unconjugated
100 µg/$962
PODXL / Podocalyxin Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (FITC) (53D11) Antibody
Human
Flo
FITC Conjugated
100 µl/$430
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (PE) (53D11) Antibody
Human
Flo
PE Conjugated
1 ml/$451
PODXL / Podocalyxin Antibody - Detection of podocalyxin in human lung lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PODXL / Podocalyxin Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
0.1 ml/$416
PODXL / Podocalyxin Antibody - Podocalyxin antibody 3D3 immunohistochemistry angiosarcoma.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (3D3) Antibody
Rat, Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
PODXL / Podocalyxin Antibody - Podocalyxin antibody 3D3 immunohistochemistry angiosarcoma.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Ready-to-Use) (3D3) Antibody
Rabbit, Rat, Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Ready-to-Use
7 ml/$574
PODXL / Podocalyxin Antibody - Podocalyxin antibody 3D3 immunohistochemistry angiosarcoma.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Azide-free, BSA-free) (3D3) Antibody
Rabbit, Rat, Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
PODXL / Podocalyxin Antibody - Anti-PODXL antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa301-350) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PODXL / Podocalyxin Antibody - Normal kidney stained with Anti-gp200
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (SPM487) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$455
PODXL / Podocalyxin Antibody - Antibody (0.5 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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PODXL / Podocalyxin Goat anti-Human Polyclonal (aa543-557) Antibody
Rabbit, Mouse, Hamster, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa410-439) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
PODXL / Podocalyxin Antibody
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (4H11) Antibody
Human
Flo, WB
Unconjugated
100 µg/$423
PODXL / Podocalyxin Antibody
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (4D2G7) Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
50 µl/$316; 100 µl/$386
PODXL / Podocalyxin Antibody - Western blot of recombinant PODXL / Podocalyxin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa220-463) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
PODXL / Podocalyxin Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded Lung Cancer Tissues (left) and kidney tissues (right) with DAB staining using Podocalyxin-like 1 Monoclonal Antibody.
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PODXL / Podocalyxin Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
PODXL / Podocalyxin Antibody - IHC of paraffin-embedded lung cancer tissues (left) and kidney tissues (right) using PODXL mouse monoclonal antibody with DAB staining.
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (5F5) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
PODXL / Podocalyxin Antibody - PODXL antibody ARP44729_T100-NP_005388-PODXL(podocalyxin-like) Antibody Western blot of HepG2 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa131-180) Antibody
Human
WB
Unconjugated
100 µl/$397
PODXL / Podocalyxin Antibody - PODXL Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The PODXL antibody detected the PODXL protein (arrow).
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PODXL / Podocalyxin Rabbit anti-Human Polyclonal (aa410-439) Antibody
Human
WB
Unconjugated
400 µl/$393
PODXL / Podocalyxin Antibody - Formalin-fixed, paraffin-embedded human angiosarcoma stained with PODXL antibody (4F10).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (4F10) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
PODXL / Podocalyxin Antibody - Formalin-fixed, paraffin-embedded human angiosarcoma stained with PODXL antibody (4F10).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Ready-to-Use) (4F10) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
PODXL / Podocalyxin Antibody - Formalin-fixed, paraffin-embedded human angiosarcoma stained with PODXL antibody (4F10).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Azide-free, BSA-free) (4F10) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
PODXL / Podocalyxin Antibody - Formalin-fixed, paraffin-embedded human angiosarcoma stained with Podocalyxin antibody (2A4).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (2A4) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
PODXL / Podocalyxin Antibody - Formalin-fixed, paraffin-embedded human angiosarcoma stained with Podocalyxin antibody (2A4).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Azide-free, BSA-free) (2A4) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
PODXL / Podocalyxin Antibody - Formalin-fixed, paraffin-embedded human angiosarcoma stained with Podocalyxin antibody (2A4).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
PODXL / Podocalyxin Mouse anti-Human Monoclonal (Extracellular Domain) (Ready-to-Use) (2A4) Antibody
Rabbit, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).