PARK7 / DJ-1

parkinson protein 7

Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death. Following removal of a C-terminal peptide, displays protease activity and enhanced cytoprotective action against oxidative stress-induced apoptosis. Stabilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7B and inhibits its deubiquitinating activity. Enhances RELA nuclear translocation. Binds to a number of mRNAs containing multiple copies of GG or CC motifs and partially inhibits their translation but dissociates following oxidative stress. Required for correct mitochondrial morphology and function and for autophagy of dysfunctional mitochondria. Regulates astrocyte inflammatory responses. Acts as a positive regulator of androgen receptor-dependent transcription. Prevents aggregation of SNCA. Plays a role in fertilization. Has no proteolytic activity. Has cell-growth promoting activity and transforming activity. May function as a redox-sensitive chaperone. May regulate lipid rafts-dependent endocytosis in astrocytes and neuronal cells.

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Products

ELISA Kits (14)

Type

Cell-Based (1)

Custom (4)

Development Kit (1)

Sandwich (8)

Target

PARK7 / DJ-1 (14)

Reactivity

Human (7)

Mouse (4)

Rat (2)

Bovine (1)

Chicken (1)

Product Group

DevKit DuoPlus (1)

Format

96-Well Microplate (2)

96-Well Strip Plate (11)

Antibody Pair and Standard (1)

Publications

No (14)

Sample Type

Adherent Cell Cultures (1)

Cell Culture Supernatants (4)

Cell Lysates (6)

Plasma (8)

Serum (9)

Tissue Homogenates (7)

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Human PARK7 / DJ-1 (Sandwich ELISA) ELISA Kit - LS-F50008

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

32 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$672

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Human PARK7 / DJ-1 (Sandwich ELISA) ELISA Kit - LS-F38947

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$974

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Human PARK7 / DJ-1 (Sandwich ELISA) ELISA Kit - LS-F32513

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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DevKit DuoPlus Mouse PARK7 / DJ-1 ELISA Development Kit - LS-F72180

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

31.2 - 2000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,327; 1000 Wells/$1,989

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Rat PARK7 / DJ-1 (Sandwich ELISA) ELISA Kit - LS-F55364

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$965

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Chicken PARK7 / DJ-1 (Custom) ELISA Kit - LS-F65265

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Price:

1 Plate/$929

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Mouse PARK7 / DJ-1 (Custom) ELISA Kit - LS-F65436

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

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Mouse PARK7 / DJ-1 (Sandwich ELISA) ELISA Kit - LS-F55210

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$923

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Human PARK7 / DJ-1 (Sandwich ELISA) ELISA Kit - LS-F50864

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.235 - 15 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Serum, Tissue Homogenates

Price:

1 Plate/$1,041

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Bovine PARK7 / DJ-1 (Custom) ELISA Kit - LS-F65682

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Price:

1 Plate/$783

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Rat PARK7 / DJ-1 (Custom) ELISA Kit - LS-F66008

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Price:

1 Plate/$783

Select

Human PARK7 / DJ-1 (Sandwich ELISA) ELISA Kit - LS-F66589

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Human PARK7 / DJ-1 (Sandwich ELISA) ELISA Kit - LS-F9726

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$902

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Mouse/Human PARK7 / DJ-1 (Cell-Based ELISA) ELISA Kit - LS-F1943

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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