Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
We could not find product '(ID:120225)'. Here are some alternate products to this target that might be of interest to you.
Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. The secreted form displays antiviral effect against vesicular stomatitis virus (VSV), herpes simplex virus type 2 (HSV-2), and encephalomyocarditis virus (EMCV) and stimulates the alternative antiviral pathway independent of RNase L.
Gene Name: | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
Synonyms: | OAS1, 2,5-oligo A synthetase 1, 2-5A synthetase 1, 2-5A synthase 1, 2-5-oligoadenylate synthase 1, E18/E16, OIASI, OIAS, p46/p42 OAS, IFI-4 |
Target Sequences: | NM_016816 NP_058132.2 P00973 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.