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Unfortunately, the antibody (ID:106031) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



NANOG

Nanog homeobox

Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.

Gene Name: Nanog homeobox
Synonyms: NANOG, Nanog homeobox, NANOGP8, HNanog, Homeobox protein NANOG
Target Sequences: AB062943 NP_079141.2 Q9H9S0

Publications (6)

1
Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Aasen T, Raya A, Barrero MJ, Garreta E, Consiglio A, Gonzalez F, Vassena R, Bili J, Pekarik V, Tiscornia G, Edel M, Bou S, Izpisa Belmonte JC. Nature biotechnology. 2008 26:1276-84. [PubMed:18931654] Related Antibodies: LS-C55142.
2
Reprogramming of human fibroblasts to induced pluripotent stem cells under xeno-free conditions. Rodrguez-Piz I, Richaud-Patin Y, Vassena R, Gonzlez F, Barrero MJ, Veiga A, Raya A, Izpisa Belmonte JC. Stem cells (Dayton, Ohio). 2010 28:36-44. [PubMed:19890879] Related Antibodies: LS-C55142.
3
Generation of pig iPS cells: a model for cell therapy. Montserrat N, Bahima EG, Batlle L, Hfner S, Rodrigues AM, Gonzlez F, Izpisa Belmonte JC. Journal of cardiovascular translational research. 2011 4:121-30. [PubMed:21088946] Related Antibodies: LS-C55142.
4
Simple generation of human induced pluripotent stem cells using poly-beta-amino esters as the non-viral gene delivery system. Montserrat N, Garreta E, Gonzlez F, Gutirrez J, Eguizbal C, Ramos V, Borrs S, Izpisua Belmonte JC. The Journal of biological chemistry. 2011 286:12417-28. [PubMed:21285354] [PMC:PMC3069445] Related Antibodies: LS-C55142.
5
Accumulation of instability in serial differentiation and reprogramming of parthenogenetic human cells. Vassena R, Montserrat N, Carrasco Canal B, Aran B, de Oate L, Veiga A, Izpisua Belmonte JC. Human molecular genetics. 2012 21:3366-73. (IHC; Human) [PubMed:22547223] [PMC:PMC3491960] Related Antibodies: LS-C55142.
6
Expansion and differentiation of germline-derived pluripotent stem cells on biomaterials. Hoss M, [Character 160]ari[Character 107] T, Denecke B, Peinkofer G, Bovi M, Groll J, Ko K, Salber J, Halbach M, Sch[Character f6]ler HR, Zenke M, Neuss S. Tissue engineering. Part A. 2013 May;19:1067-80. [Full Text Article] [PubMed:23234562] [PMC:PMC3609644] Related Antibodies: LS-B1193.
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Filtered By: None
Target
nanog (110)
Reactivity
Human (105)
Mouse (12)
Rat (6)
Bovine (8)
Chimpanzee (15)
Gibbon (15)
Goat (1)
Macaque (1)
Monkey (18)
Orangutan (3)
Pig (4)
Sheep (8)
Application
IHC (20)
IHC-P (13)
WB (87)
Flo (12)
ChrIP (1)
DB (16)
ELISA (62)
ICC (16)
IF (30)
IP (3)
Host
rabbit (92)
mouse (16)
goat (2)
Isotype
IgG (59)
IgG1 (4)
IgG1,k (8)
IgG2a,k (2)
Clonality
monoclonal mc (16)
polyclonal pc (94)
Clone
1E6C4 (2)
23D2-3C6 (1)
2C4 (1)
5A10 (1)
60CT77.1.1 (7)
hNanog.2 (1)
Format
AP Conjugated (6)
APC Conjugated (6)
Azide-free (5)
Biotin Conjugated (15)
FITC Conjugated (13)
HRP Conjugated (12)
PE Conjugated (6)
Unconjugated (52)
Epitope
Ser285 (12)
aa24-73 (8)
aa101-131 (6)
Ser71 (5)
aa135-184 (4)
aa21-70 (4)
aa35-84 (4)
aa1-305 (3)
aa1-50 (3)
C-Terminus (2)
Internal (2)
aa1-154 (2)
aa20-166 (2)
pSer285 (2)
pSer71 (2)
Asn156 (1)
aa137-141 (1)
aa144-157 (1)
aa15-49 (1)
aa155-189 (1)
aa281-296 (1)
aa291-304 (1)
aa51-100 (1)
aa94-123 (1)
Publications
No (108)
Yes (2)
Showing 1-25 out of 110 results
Anti-NANOG Antibody (aa24-73) IHC-plus™ LS-B1193

Rabbit Polyclonal to Human NANOG
Human, Monkey
IHC-P WB
Unconjugated
Anti-NANOG Antibody (aa94-123) IHC-plus™ LS-B3425

Rabbit Polyclonal to Human NANOG
Human
Flo IF IHC-P WB
Unconjugated
Anti-NANOG Antibody (aa291-304) IHC-plus™ LS-B3017

Goat Polyclonal to Human NANOG
Human
ELISA IHC-P WB
Unconjugated
Anti-NANOG Antibody (aa144-157) LS-C55142

Goat Polyclonal to Human NANOG
Human, Monkey
ELISA WB
Unconjugated
Anti-NANOG Antibody (clone hNanog.2) IHC-plus™ LS-B7871

Mouse Monoclonal [clone hNanog.2] (IgG1,k) to Human NANOG
Human
Flo IHC-P WB
Unconjugated
Anti-NANOG Antibody (clone 1E6C4) LS-C108845

Mouse Monoclonal [clone 1E6C4] (IgG1) to Human NANOG
Human
ELISA IF WB
Unconjugated
Anti-NANOG Antibody (clone 2C4) LS-C348865

Mouse Monoclonal [clone 2C4] (IgG) to Human NANOG
Human
ELISA Flo IF IHC WB
Unconjugated
Anti-NANOG Antibody (Biotin) LS-C104594

Rabbit Polyclonal to Human NANOG
Human
ELISA WB
Biotin Conjugated
Anti-NANOG Antibody (aa101-131) LS-C323228

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA Flo IF IHC WB
Unconjugated
Anti-NANOG Antibody (Biotin) LS-C520377

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA Flo IF IHC WB
Biotin Conjugated
Anti-NANOG Antibody (aa101-131, FITC) LS-C263953

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA Flo ICC IF IHC WB
FITC Conjugated
Anti-NANOG Antibody (aa101-131, APC) LS-C263952

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA Flo ICC IF IHC WB
APC Conjugated
Anti-NANOG Antibody (aa101-131, AP) LS-C263951

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA Flo ICC IF IHC WB
AP Conjugated
Anti-NANOG Antibody (aa101-131, PE) LS-C263957

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA Flo ICC IF IHC WB
PE Conjugated
Anti-NANOG Antibody (aa101-131, Azide-free, HRP) LS-C263954

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA Flo ICC IF IHC WB
HRP Conjugated, Azide-free
Anti-NANOG Antibody (aa20-166, clone 1E6C4) LS-C359267

Mouse Monoclonal [clone 1E6C4] (IgG1) to Human NANOG
Human
ELISA ICC IF WB
Unconjugated
Anti-NANOG Antibody (aa15-49) LS-C98243

Rabbit Polyclonal to Human NANOG
Human
Flo IF IHC-P WB
Unconjugated
Anti-NANOG Antibody LS-C417207

Rabbit Polyclonal to Human NANOG
Mouse, Rat, Human
ICC IF IHC WB
Unconjugated
Anti-NANOG Antibody (clone 23D2-3C6) LS-C355122

Mouse Monoclonal [clone 23D2-3C6] (IgG) to Human NANOG
Human
Flo IF WB
Unconjugated
Anti-NANOG Antibody LS-C355550

Rabbit Polyclonal (IgG) to Human NANOG
Human
ChrIP IF IHC-P WB
Unconjugated
Anti-NANOG Antibody IHC-plus™ LS-B8225

Rabbit Polyclonal to Human NANOG
Human
ELISA IHC-P WB
Unconjugated
Anti-NANOG Antibody (Ser285, FITC) LS-C263948

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA ICC IF WB
FITC Conjugated
Anti-NANOG Antibody (Ser285, AP) LS-C263946

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA ICC IF WB
AP Conjugated
Anti-NANOG Antibody (Ser285, APC) LS-C263947

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA ICC IF WB
APC Conjugated
Anti-NANOG Antibody (Ser285, PE) LS-C263950

Rabbit Polyclonal (IgG) to Human NANOG
Human
ELISA ICC IF WB
PE Conjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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