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MYO5A / Myosin V

myosin VA (heavy chain 12, myoxin)

MYO5A / Myosin V is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

Gene Name: myosin VA (heavy chain 12, myoxin)
Synonyms: MYO5A, GS1, Myosin heavy chain 12, Myosin V, Myosin-12, MYO5, Myoxin, MYR12, MYH12, Myosin-Va, Unconventional myosin-Va
Target Sequences: NM_000259 NP_000250.3 Q9Y4I1

Publications (1)

1
Herpes simplex virus-1 utilizes the host actin cytoskeleton for its release from axonal growth cones. Kevin Danastas, Ava Larsen, Sophie Jobson, Gerry Guo, Anthony L Cunningham, Monica Miranda-Saksena. PLoS pathogens. 2022 January;18:e1010264. [Full Text Article] [PubMed:35073379] [PMC:PMC8812851] Related Antibodies: LS-C139627.

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Proteins (2)
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MYO5A / Myosin V (2)
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GST, N-terminus (1)
His-T7 (1)
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E. coli (1)
Wheat Germ Extract (1)
MYO5A / Myosin V Protein - Recombinant Myosin VA By SDS-PAGE
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E. coli
His-T7
40.9 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
MYO5A / Myosin V Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).