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MYB / c-Myb

v-myb avian myeloblastosis viral oncogene homolog

MYB / c-Myb is a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.

Gene Name: v-myb avian myeloblastosis viral oncogene homolog
Synonyms: MYB, C-myb_CDS, C-myb8B_CDS, C-myb protein (140 AA), C-myb10A_CDS, C-myb13A_CDS, Efg, Transcriptional activator Myb, C-myb, C-myb14A_CDS, Cmyb, Proto-oncogene c-Myb
Target Sequences: NM_005375 NP_005366.2 P10242

Publications (4)

1
Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome. Hussein K, Theophile K, Bsche G, Schlegelberger B, Ghring G, Kreipe H, Bock O. Leukemia research. 2010 34:328-34. (IHC) [PubMed:19615744]
2
The Expression of c-Myb Correlates with the Levels of Rhabdomyosarcoma-specific Marker Myogenin. Kaspar P, Zikova M, Bartunek P, Sterba J, Strnad H, Kren L, Sedlacek R. Scientific reports. 2015 5:15090. (IHC; Mouse) [Full Text Article] [PubMed:26462877] [PMC:PMC4604482] Related Antibodies: LS-B5315.
3
Aberrant expression of AID and AID activators of NF-?B and PAX5 is irrelevant to EBV-associated gastric cancers, but is associated with carcinogenesis in certain EBV-non-associated gastric cancers. Mohri T, Nagata K, Kuwamoto S, Matsushita M, Sugihara H, Kato M, Horie Y, Murakami I, Hayashi K. Oncology letters. 2017 13:4133-4140. (ICC; Human) [Full Text Article] [PubMed:28588701] [PMC:PMC5452920]
4
Higher Expression of Activation-induced Cytidine Deaminase Is Significantly Associated with Merkel Cell Polyomavirus-negative Merkel Cell Carcinomas. Matsushita M, Iwasaki T, Nonaka D, Kuwamoto S, Nagata K, Kato M, Kitamura Y, Hayashi K. Yonago acta medica. 2017 September;60:145-153. [Full Text Article] [PubMed:28959124] [PMC:PMC5611468]
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☰ Filters
Antibodies (106)
ELISA Kits (8)
Proteins (8)
Cell-Based (1)
Cell-Based Phosphorylation (1)
Custom (3)
DNA Binding Phosphorylation (1)
Over-Expression Lysate (4)
Primary (106)
Recombinant (4)
Sandwich (2)
MYB / c-Myb (122)
Human (97)
Mouse (71)
Rat (3)
Bat (5)
Bovine (5)
Chicken (5)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (4)
Horse (6)
Monkey (6)
Pig (6)
Rabbit (5)
Xenopus (1)
Zebrafish (4)
IHC (40)
IHC-P (23)
WB (90)
Flo (2)
ELISA (36)
ICC (2)
IF (7)
IP (15)
Peptide-ELISA (8)
rabbit (76)
mouse (24)
goat (5)
sheep (1)
Product Group
IHCPlus (4)
IgG (43)
IgG1 (5)
IgG1,k (3)
IgG2a (9)
IgG2a,k (7)
monoclonal mc (24)
polyclonal pc (82)
10A3 (1)
1279CT309.289 (1)
4E3 (2)
7C3 (1)
MYB286 (2)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (5)
AP Conjugated (4)
APC (2)
APC Conjugated (5)
Azide-free (4)
Biotin Conjugated (9)
BSA-free (1)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (9)
Gold Conjugated (1)
HRP Conjugated (9)
PE Conjugated (6)
Unconjugated (59)
C-Terminus (14)
aa305-558 (8)
aa35-291 (8)
aa419-448 (8)
aa26-75 (4)
pSer532 (4)
1-80 aa (2)
470-550 aa (2)
Internal (2)
aa119-135 (2)
pSer12 (2)
pThr486 (2)
Arg6 (1)
Ile526 (1)
N-Terminus (1)
aa1-185 (1)
aa1-201 (1)
aa1-50 (1)
aa241-254 (1)
aa281-294 (1)
aa496-545 (1)
aa503-552 (1)
aa557-569 (1)
aa591-640 (1)
p12 (1)
p532 (1)
No (121)
Yes (1)
Adherent Cell Cultures (2)
Cell Lysates (1)
Nuclear Lysates (1)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (5)
Mouse (1)
293T Cells (2)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
MYB / c-Myb Antibody - Anti-c-Myb antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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MYB / c-Myb Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
MYB / c-Myb Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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MYB / c-Myb Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
MYB / c-Myb ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$746
MYB / c-Myb Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYB / c-Myb Rabbit anti-Human Polyclonal (aa26-75) Antibody
Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$485
MYB / c-Myb Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYB / c-Myb Rabbit anti-Human Polyclonal (aa26-75) (FITC) Antibody
Chicken, Zebrafish, Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
MYB / c-Myb ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$744
MYB / c-Myb Antibody - Western blot of c-Myb antibody
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MYB / c-Myb Rabbit anti-Human Polyclonal (1-80 aa) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µl/$289; 100 µl/$319; 200 µl/$389
MYB / c-Myb Antibody - IHC of MYB (R6) pAb in paraffin-embedded human breast carcinoma tissue.
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MYB / c-Myb Rabbit anti-Human Polyclonal (Arg6) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$404
MYB / c-Myb Protein - 12.5% SDS-PAGE of human MYB stained with Coomassie Blue
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Wheat Germ Extract
GST
98.7 kDa
2 µg/$439
MYB / c-Myb Protein - Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog By SDS-PAGE
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E. coli
6His, N-terminus
32.0 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$3,201
MYB / c-Myb Antibody - Goat anti-MYB / c-myb Antibody (2µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
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MYB / c-Myb Goat anti-Human Polyclonal (aa281-294) Antibody
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µg/$467
MYB / c-Myb Antibody - Formalin-fixed, paraffin-embedded human seminoma stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MYB / c-Myb Mouse anti-Human Monoclonal (4E3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$329; 0.5 ml/$542; 1 ml/$841
MYB / c-Myb Antibody - Formalin-fixed, paraffin-embedded human seminoma stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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MYB / c-Myb Mouse anti-Human Monoclonal (Azide-free) (4E3) Antibody
Human
IHC, IHC-P, WB
Unconjugated, Azide-free
0.1 ml/$570
MYB / c-Myb Antibody - Anti-C-Myb Antibody - Western Blot. Western blot of affinity purified anti-C-Myb antibody in Cos7 cell lysates: Lane 1: vector; Lane 2: transfected with c-myb, no treatment; Lane 3: transfected with c-Myb and heat stress-treated (incubation at 42oC for 30 minutes) to induce c-Myb modification. Lane 3 shows detection of bands at 75, 98, and 125kD corresponding to overexpressed c-Myb (arrows): wild-type, with one attached SUMO molecule, and with two attached SUMO molecules, respectively. Nitrocellulose 0.45mum membrane was blocked for 1 hr at RT in 10% BLOTTO in PBS. The primary antibody was used at 1:500. Personal communication, J. Bies, NCI NIH, Bethesda.
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MYB / c-Myb Rabbit anti-Mouse Polyclonal (Internal) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$510
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MYB / c-Myb Mouse anti-Human Monoclonal (aa119-135) (MYB286) Antibody
Human
Flo
Unconjugated
20 µg/$364; 100 µg/$560
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MYB / c-Myb Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
250 µl/$481
MYB / c-Myb Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using MYB (Ab-12) antibody.
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MYB / c-Myb Rabbit anti-Human Polyclonal (p12) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
MYB / c-Myb Antibody - 1:100 staining human Testis tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MYB / c-Myb Rabbit anti-Human Polyclonal (pSer532) Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MYB / c-Myb Antibody - Anti-c-Myb antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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MYB / c-Myb Goat anti-Human Polyclonal (aa241-254) Antibody
Rabbit, Dog, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
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MYB / c-Myb Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
200 µl/$642
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MYB / c-Myb Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
200 µl/$854
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MYB / c-Myb Rabbit anti-Human Polyclonal (C-Terminus) (AP) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
AP Conjugated
200 µl/$854
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MYB / c-Myb Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
APC Conjugated
200 µl/$854
MYB / c-Myb Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MYB / c-Myb Protein - Recombinant V-Myb Myeloblastosis Viral Oncogene Homolog By SDS-PAGE
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E. coli
His-T7
33.5 kDa
50 µg/$437; 10 µg/$280; 200 µg/$872; 100 µg/$700; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,489
Viewing 1-25 of 122 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).