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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-C391542-20 20 µg (0.2 mg/ml) $295 
LS-C391542-100 100 µg (0.2 mg/ml) $465 
Antibody

Monoclonal MYB / c‑Myb Antibody (clone MYB286, aa119‑135) LS‑C391542

Monoclonal MYB / c‑Myb Antibody (clone MYB286, aa119‑135) LS‑C391542

Antibody:
Mouse Monoclonal to Human MYB / c-Myb
Application:
Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$295 
LS-C391542-20
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Mouse Monoclonal to Human MYB / c-Myb
Application:
Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
C-Myb antibody LS-C391542 is an unconjugated mouse monoclonal antibody to human c-Myb (MYB) (aa119-135). Validated for Flow.
Target
Human MYB / c-Myb
Synonyms
MYB | C-myb_CDS | C-myb8B_CDS | C-myb protein (140 AA) | C-myb10A_CDS | C-myb13A_CDS | Efg | Transcriptional activator Myb | C-myb | C-myb14A_CDS | Cmyb | Proto-oncogene c-Myb
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Chicken (at least 90% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Clone
MYB286
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified. Also available Azide-free.
Applications
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
Immunogen
Synthetic peptide (RRKVEQEGYPQESSKAG, aa119-135 of UniProt P01104) from the human protein. Percent identity by BLAST analysis: Chicken (94%); Human, Ferret, Sheep, Bovine, Pig, Turkey (88%).
Epitope
aa119-135
Specificity
Human MYB / c-Myb
Usage
The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate. The optimal dilution of the c-Myb antibody for each application should be determined by the researcher.
Presentation
0.01% BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MYB / c-Myb
P10242 NM_005375 NP_005366.2

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Requested From: United States
Date Requested: 4/4/2020