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Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
Gene Name: | lysosomal-associated membrane protein 2 |
Family/Subfamily: | Cancer |
Synonyms: | LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2 |
Target Sequences: | NM_013995 NP_054701.1 P13473 |
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