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KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
| Gene Name: | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| Synonyms: | KMO, DJ317G22.1, Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase |
| Target Sequences: | NM_003679 NP_003670.2 O15229 |
Publications (1)
1
Kynurenine 3-monooxygenase upregulates pluripotent genes through ß-catenin and promotes triple-negative breast cancer progression. Tzu-Ting Huang, Ling-Ming Tseng, Ji-Lin Chen, Pei-Yi Chu, Chia-Han Lee, Chun-Teng Huang, Wan-Lun Wang, Ka-Yi Lau, Mei-Fang Tseng, Yuan-Ya Chang, Tzu-Yi Chiang, Yune-Fang Ueng, Hsin-Chen Lee, Ming-Shen Dai, Chun-Yu Liu. EBioMedicine. 2020 Apr;54:102717. [Full Text Article]
[PubMed:32268268]
[PMC:PMC7191260]
Related Antibodies: LS-C165595.
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KMO Rabbit anti-Human Polyclonal (aa155-182) Antibody
Mouse, Human
Flo, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
400 µl/$393
KMO Rabbit anti-Mouse Polyclonal (aa300-400) Antibody
Mouse, Human
WB
Unconjugated
100 µg/$567
KMO Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KMO Rabbit anti-Human Polyclonal (aa1-260) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
KMO Rabbit anti-Human Polyclonal (aa135-184) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
KMO Rabbit anti-Mouse Polyclonal (aa200-300) Antibody
Mouse
ELISA, IF, IHC, WB
Unconjugated
100 µg/$567
KMO Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
KMO Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
KMO Rabbit anti-Human Polyclonal (aa1-486) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
KMO Rabbit anti-Human Polyclonal (aa1-486) (HRP) Antibody
Human
ELISA, IHC, IHC-P
HRP Conjugated
50 µg/$294; 100 µg/$360
KMO Rabbit anti-Human Polyclonal (aa1-486) (Biotin) Antibody
Human
ELISA, IHC, IHC-P
Biotin Conjugated
50 µg/$294; 100 µg/$360
KMO Rabbit anti-Human Polyclonal (aa1-486) (FITC) Antibody
Human
ELISA, IHC, IHC-P
FITC Conjugated
50 µg/$294; 100 µg/$360
KMO Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$567
KMO Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$567
KMO Rabbit anti-Mouse Polyclonal (aa200-375) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$567
KMO Rabbit anti-Human Polyclonal (aa155-182) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
KMO Rabbit anti-Human Polyclonal (aa155-182) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
KMO Rabbit anti-Human Polyclonal (aa155-182) (Azide-free) Antibody
Human
ELISA, WB
Unconjugated, Azide-free
200 µl/$734
KMO Rabbit anti-Human Polyclonal (aa155-182) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
KMO Rabbit anti-Human Polyclonal (aa155-182) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
KMO Rabbit anti-Human Polyclonal (aa155-182) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
KMO Goat anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
KMO Goat anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
KMO Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
KMO Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
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