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Catalog Number Size Price
LS-C43306-0.1 0.1 mg (1 mg/ml) $363 
Antibody

Monoclonal Mouse anti‑Human IL6ST / CD130 / gp130 Antibody (clone B‑T2) LS‑C43306

Monoclonal Mouse anti‑Human IL6ST / CD130 / gp130 Antibody (clone B‑T2) LS‑C43306

Antibody:
IL6ST / CD130 / gp130 Mouse anti-Human Monoclonal (B-T2) Antibody
Application:
Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$363
LS-C43306-0.1
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
IL6ST / CD130 / gp130 Mouse anti-Human Monoclonal (B-T2) Antibody
Application:
Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Gp130 antibody LS-C43306 is an unconjugated mouse monoclonal antibody to human gp130 (IL6ST / CD130). Validated for ELISA and Flow.
Target
Human IL6ST / CD130 / gp130
Synonyms
IL6ST | CD130 | CD130 antigen | IL-6R subunit beta | IL-6 receptor subunit beta | Membrane glycoprotein gp130 | Membrane glycoprotein 130 | IL-6RB | CDW130 | gp130 | IL-6R-beta
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
B-T2
Conjugations
Unconjugated
Purification
Ion exchange chromatography
Modifications
Unmodified
Immunogen
Natural soluble gp130 receptor.
Specificity
Recognizes soluble and membrane bound gp130 receptor, also known as CD130, Interleukin-6 receptor subunit beta, Oncostatin-M receptor subunit alpha or Interleukin-6 signal transducer. CD130 is a 918 amino acid, ~130 kD single pass type-1 transmembrane glycoprotein containing a single and multiple domains. CD130 can be cleaved to form a monomeric soluble ~100 kD form of the receptor detectable in plasma and other biologic fluids where it acts as an IL-6 antagonist. Binds to an epitope dependent at least partially on the presence of the Ig-like domain. Has been reported to block receptor activity and inhibit IL-6 induced proliferation of XG1 cells and IL-27 mediated proliferation of naive CD4+ T cells,.
Applications
  • Flow Cytometry
  • ELISA
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About IL6ST / CD130 / gp130
P40189 NM_002184 NP_002175.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/27/2021