Menu
Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

IL-10

interleukin 10

IL-10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Gene Name: interleukin 10
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL10, CSIF, GVHDS, IL-10, IL10A, Interleukin-10, Interleukin 10, TGIF
Target Sequences: NM_000572 NP_000563.1 P22301

Publications (2)

1
Antibodies to human IL-10 neutralize ebvIL-10-mediated cytokine suppression but have no effect on cmvIL-10 activity. Brodeur ND, Spencer JV. Virus research. 2010 153:265-8. (WB; Human) [Full Text Article] [PubMed:20728483] [PMC:PMC3769974] Related Antibodies: LS-C47137.
2
Skin-Derived Mesenchymal Stem Cells Alleviate Atherosclerosis via Modulating Macrophage Function. Li Q, Sun W, Wang X, Zhang K, Xi W, Gao P. Stem cells translational medicine. 2015 November;4:1294-301. (Mouse) [Full Text Article] [PubMed:26400926] [PMC:PMC4622403] Related Antibodies: LS-B4913.

Viewing 1-25 of 88 items
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 pg/ml
Colorimetric - 450nm (TMB)
Serum
1plate   $810.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate   $780.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate   $690.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
2.344 - 150 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1plate   $470.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Microplate
Chicken
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate   $580.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Microplate
Rabbit
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate   $580.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate   $690.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Hamster
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate   $555.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1plate   $580.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate   $700.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate   $510.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate   $560.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1plate   $470.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate   $780.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1plate   $390.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate   $550.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Microplate
Dog, Canine
0.11 - 80 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1plate   $470.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Microplate
Rhesus monkey
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate   $900.00
IL-10 ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
32 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1plate   $490.00
IL-10 ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Mouse
47 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1plate   $490.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Microplate
Feline, Cat
0.205 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1plate   $470.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
8.23 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1plate   $470.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Goat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate   $550.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
9.38 - 600 pg/ml
Colorimetric - 450nm (TMB)
Cell Supernatant
1plate   $390.00
IL-10 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate   $770.00

Viewing 1-25 of 88 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).