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Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
|Gene Name:||insulin-like growth factor binding protein 2, 36kDa|
|Synonyms:||IGFBP2, BP2, IGFBP-2, IGF-binding protein 2, IBP-2, IBP2, IGF-BP53|
|Target Sequences:||NM_000597 NP_000588.2 P18065|
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