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IGFBP2 / IGF-BP53

insulin-like growth factor binding protein 2, 36kDa

Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Gene Name: insulin-like growth factor binding protein 2, 36kDa
Synonyms: IGFBP2, BP2, IGFBP-2, IGF-binding protein 2, IBP-2, IBP2, IGF-BP53
Target Sequences: NM_000597 NP_000588.2 P18065

Publications (1)

1
Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressiveness. French CL, Ye F, Revetta F, Zhang B, Coffey RJ, Washington MK, Deane NG, Beauchamp RD, Weaver AM. F1000Research. 2015 4:99. (WB; Human) [Full Text Article] [PubMed:26097693] [PMC:PMC4457132]

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Products
Antibodies (75)
Primary (75)
IGFBP2 / IGF-BP53 (75)
Human (57)
Mouse (29)
Rat (18)
Bat (3)
Bovine (8)
Chicken (3)
Chimpanzee (5)
Cynomolgus (3)
Dog (2)
Gibbon (5)
Goat (3)
Guinea pig (5)
Horse (3)
Monkey (3)
Monkey-Rhesus (1)
Pig (7)
Rabbit (5)
Rhesus monkey (1)
Sheep (7)
IHC (14)
IHC-P (11)
WB (69)
Flo (3)
ELISA (20)
IF (1)
IP (6)
rabbit (65)
mouse (10)
Product Group
IHCPlus (2)
IgG (28)
IgG1 (6)
IgM (1)
monoclonal mc (10)
polyclonal pc (65)
05 (1)
106 (1)
1F6F6 (2)
OTI1A7 (2)
APC (3)
APC Conjugated (5)
Azide-free (1)
Biotin Conjugated (8)
Carrier-free (1)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (8)
HRP Conjugated (8)
PE Conjugated (5)
Preservative Free (2)
Unconjugated (35)
aa148-325 (8)
aa24-305 (8)
aa35-304 (8)
aa277-305 (7)
Internal (4)
aa182-231 (4)
aa215-264 (4)
Amino Acid: 180-328 (1)
C-Terminus (1)
aa195-212 (1)
aa228-257 (1)
No (75)
IGFBP2 / IGF-BP53 Antibody - Anti-IGFBP2 / IGF-BP53 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (aa277-305) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
IGFBP2 / IGF-BP53 Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (aa215-264) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
IGFBP2 / IGF-BP53 Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (aa215-264) (HRP) Antibody
Mouse, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
IGFBP2 / IGF-BP53 Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (aa215-264) (Biotin) Antibody
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
IGFBP2 / IGF-BP53 Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (aa215-264) (FITC) Antibody
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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IGFBP2 / IGF-BP53 Rabbit anti-Bovine Polyclonal Antibody
Mouse, Bovine, Rat, Human
ELISA, IP, WB
Unconjugated
100 µl/$801
IGFBP2 / IGF-BP53 Antibody - IHC of paraffin-embedded human lung cancer (A), recturn(B), prostate (C), colon cancer (D) showing cytoplasmic localization using IGFBP2 mouse monoclonal antibody with DAB staining.
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IGFBP2 / IGF-BP53 Mouse anti-Human Monoclonal (1F6F6) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$467
IGFBP2 / IGF-BP53 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IGFBP2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IGFBP2.
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IGFBP2 / IGF-BP53 Mouse anti-Human Monoclonal (OTI1A7) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
IGFBP2 / IGF-BP53 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IGFBP2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IGFBP2.
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IGFBP2 / IGF-BP53 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A7) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
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IGFBP2 / IGF-BP53 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$842
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IGFBP2 / IGF-BP53 Rabbit anti-Mouse Monoclonal (Preservative Free) (106) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
IGFBP2 / IGF-BP53 Antibody - HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (aa182-231) Antibody
Human
WB
Unconjugated
100 µl/$424
IGFBP2 / IGF-BP53 Antibody - Western blot of IGFBP2 / IGF-BP53 antibody.
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (aa148-325) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$275; 200 µl/$303; 500 µl/$396; 1 ml/$443; 2 ml/$535; 5 ml/$907
IGFBP2 / IGF-BP53 Antibody - Immunohistochemistry - Anti-IGFBP2 Picoband Antibody
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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IGFBP2 / IGF-BP53 Rabbit anti-Mouse Polyclonal Antibody
Mouse
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$412
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$351
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$688
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IGFBP2 / IGF-BP53 Rabbit anti-Cynomolgus Polyclonal Antibody
Cynomolgus
ELISA, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$412
IGFBP2 / IGF-BP53 Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded human lung cancer (A), recturn(B), prostate (C), colon cancer (D) showing cytoplasmic localization with DAB staining using IGFBP2 Monoclonal Antibody.
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IGFBP2 / IGF-BP53 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
IGFBP2 / IGF-BP53 Antibody - IHC analysis of IGFBP2 using anti-IGFBP2 antibody. IGFBP2 was detected in paraffin-embedded section of mouse small intestine tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2?g/ml rabbit anti-IGFBP2 Antibody overnight at 4?C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37?C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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IGFBP2 / IGF-BP53 Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat
ELISA, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
IGFBP2 / IGF-BP53 Antibody - IGFBP2 Antibody in Immunohistochemistry (IHC)
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IGFBP2 / IGF-BP53 Mouse anti-Human Monoclonal (Amino Acid: 180-328) (1F6F6) Antibody
Human
IHC, WB
Unconjugated
100 µl/$518
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (aa277-305) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (aa277-305) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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IGFBP2 / IGF-BP53 Rabbit anti-Human Polyclonal (aa277-305) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).