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IGF2R / CD222

insulin-like growth factor 2 receptor

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

Gene Name: insulin-like growth factor 2 receptor
Synonyms: IGF2R, CD222 antigen, CIMPR, CI Man-6-P receptor, CI-MPR, IGF-II receptor, MPR 300, MPR1, MPRI, M6P-R, M6P/IGF2R, CD222, M6P/IGF2 receptor
Target Sequences: NM_000876 NP_000867.2 P11717

Publications (1)

1
Secretion of parathyroid hormone may be coupled to insulin secretion in humans. Marie Reeberg Sass, Nicolai Jacob Wewer Albrechtsen, Jens Pedersen, Kristine Juul Hare, Nis Borbye-Lorenzen, Katalin Kiss, Tina Vilsbøll, Filip Krag Knop, Steen Seier Poulsen, Niklas Rye Jørgensen, Jens Juul Holst, Cathrine Ørskov, Bolette Hartmann. Endocrine connections. 2020 July;9:747-754. [Full Text Article] [PubMed:32698134] [PMC:PMC7424341]

☰ Filters
Products
Antibodies (83)
Primary (83)
IGF2R / CD222 (83)
Human (64)
Mouse (30)
Rat (18)
Bovine (3)
Guinea pig (1)
Monkey (7)
Non-Human Primate (5)
Non-Human Primates (4)
Primate (1)
Rhesus monkey (1)
IHC (17)
IHC-P (13)
WB (61)
Flo (23)
ELISA (14)
ICC (3)
IF (11)
IP (9)
Peptide-ELISA (4)
rabbit (57)
mouse (26)
Product Group
IHCPlus (1)
IgG (18)
IgG1 (23)
IgG2a (1)
IgG2a,k (1)
IgG2b (1)
monoclonal mc (26)
polyclonal pc (57)
2G11 (2)
4F1G1 (1)
7B5E10 (1)
MEM-238 (14)
MEM-240 (2)
AF647 Conjugated (1)
APC (4)
APC Conjugated (6)
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Unconjugated (41)
aa1146-1363 (8)
aa1148-1365 (8)
aa2167-2442 (8)
aa27-185 (8)
pSer2409 (3)
2251-2300 aa, C-terminal (1)
2350-2430 aa (1)
Ab-2409 (1)
C-Terminus (1)
Extracellular Domain (1)
Phe2480 (1)
aa1510-2108 (1)
aa2381-2430 (1)
aa2441-2490 (1)
aa2475-2491 (1)
pSer2484 (1)
No (83)
IGF2R / CD222 Antibody - Flow cytometry detection of CD222 in human peripheral blood with anti-CD222 (MEM-240) purified, GAM-APC.
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IGF2R / CD222 Mouse anti-Human Monoclonal (MEM-240) Antibody
Human
Flo, IP, WB
Unconjugated
0.1 mg/$316
IGF2R / CD222 Antibody - Anti-IGF2R antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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IGF2R / CD222 Rabbit anti-Human Polyclonal (aa2441-2490) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
IGF2R / CD222 Antibody - Western blot analysis using CD222 mAb against HEK293 (1) and CD222 (AA: 160-311)-hIgGFc transfected HEK293 (2) cell lysate.
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IGF2R / CD222 Mouse anti-Human Monoclonal (4F1G1) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
IGF2R / CD222 Antibody - Immunohistochemical analysis of CD222 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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IGF2R / CD222 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Bovine, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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IGF2R / CD222 Mouse anti-Human Monoclonal (PE) (MEM-238) Antibody
Mouse, Human, Non-Human Primate
Flo
PE Conjugated
100 Tests/$493
IGF2R / CD222 Antibody - Western Blotting analysis (non-reducing conditions) of CD222 in whole cell lysate of JURKAT human peripheral blood T cell leukemia cell line.  Lane 1: immunostaining with anti-CD222 (MEM-238)  Lane 2: immunostaining with Isotype mouse IgG1 control (PPV-06)
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IGF2R / CD222 Mouse anti-Human Monoclonal (MEM-238) Antibody
Human, Non-Human Primates
Flo, IP, WB
Unconjugated
0.1 mg/$316
Select
IGF2R / CD222 Mouse anti-Human Monoclonal (APC) (MEM-238) Antibody
Human, Non-Human Primates
Flo, IP, WB
APC Conjugated
100 Tests/$365
IGF2R / CD222 Antibody - Immunohistochemistry: Mannose 6 Phosphate Receptor (Cation independent) Antibody (2G11) - Staining of human testis using antibody at 1:100.
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IGF2R / CD222 Mouse anti-Bovine Monoclonal (2G11) Antibody
Mouse, Bovine, Rat, Primate, Human
ELISA, Flo, ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$386
IGF2R / CD222 Antibody - Immunohistochemistry - Anti-IGF2R Picoband antibody
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IGF2R / CD222 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
IGF2R / CD222 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$351
IGF2R / CD222 Antibody - IGF2R / CD222 antibody. IHC(P): Human Intestinal Cancer Tissue.
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IGF2R / CD222 Rabbit anti-Human Polyclonal (aa2475-2491) Antibody
Guinea pig, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
IGF2R / CD222 Antibody - Immunohistochemistry of paraffin-embedded human placenta using IGF2R antibody at dilution of 1:100 (40x lens).
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IGF2R / CD222 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
IGF2R / CD222 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using IGF2R Antibody. The picture on the right is blocked with the synthesized peptide.
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IGF2R / CD222 Rabbit anti-Human Polyclonal (aa2381-2430) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
IGF2R / CD222 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using IGF2R antibody.
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IGF2R / CD222 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
IGF2R / CD222 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using IGF2R antibody.
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IGF2R / CD222 Rabbit anti-Human Polyclonal (Ab-2409) Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
IGF2R / CD222 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using IGF2R (Phospho-Ser2409) Antibody. The picture on the right is blocked with the phospho peptide.
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IGF2R / CD222 Rabbit anti-Human Polyclonal (pSer2409) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IGF2R / CD222 Antibody - IHC of IGF-2R (F2480) pAb in paraffin-embedded human lung carcinoma tissue.
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IGF2R / CD222 Rabbit anti-Human Polyclonal (Phe2480) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
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IGF2R / CD222 Rabbit anti-Human Polyclonal (2350-2430 aa) Antibody
Mouse, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
IGF2R / CD222 Mouse anti-Human Monoclonal (MEM-238) Antibody
Human
Flo, IF
Unconjugated
25 µg/$301; 0.2 mg/$545
IGF2R / CD222 Antibody
Select
IGF2R / CD222 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
IGF2R / CD222 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using IGF2R (Phospho-Ser2409) antibody.
Select
IGF2R / CD222 Rabbit anti-Human Polyclonal (pSer2409) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
Select
IGF2R / CD222 Mouse anti-Bovine Monoclonal (Extracellular Domain) (2G11) Antibody
Bovine, Human
IF, IP, WB
Unconjugated
100 µg/$649
IGF2R / CD222 Antibody - Western blot analysis using CD222 mAb against HEK293 (1) and CD222 (AA: 160-311)-hIgGFc transfected HEK293 (2) cell lysate.
Select
IGF2R / CD222 Mouse anti-Human Monoclonal (7B5E10) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$459
IGF2R / CD222 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue using IGF2R (Phospho-Ser2409) antibody.
Select
IGF2R / CD222 Rabbit anti-Human Polyclonal (pSer2409) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$391
Select
IGF2R / CD222 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).