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Unfortunately, the antibody (ID:154317) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



HNF4A / HNF4

hepatocyte nuclear factor 4, alpha

Hepatocyte nuclear factor 4 alpha (HNF4 alpha), a NR2 Hepatocyte NF4-Like receptor, is a liver-enriched transcription factor that is involved in the expression of liver-specific genes. HNF4 alpha controls the expression of transcription factor HNF1, which is important in the expression of hepatic genes, including those involved in glucose, cholesterol, and fatty acid metabolism. HNF4 alpha is essential for hepatocyte differentiation during liver development, metabolic regulation, and liver function. Although HNF4 alpha is a tissue-specific transcription factor, it is also an essential regulator of early embryonic events. Mutations in the HNF4 alpha gene are responsible for type-1 maturity-onset diabetes of the young (MODY1), which is characterized by a defect in insulin secretion. Mutations in HNF4 alpha binding sites have been linked to hemophilia B Leyden, atherosclerosis, hepatitis, and other diseases. HNF4 alpha has been linked to liver cancer via hepatitis and hepatitis B viral infections. Mouse embryos lacking HNF4 alpha fail to complete gastrulation due to dysfunction of the visceral endoderm. Recently, it has been shown that HNF4 alpha is critically involved in the PXR- and CAR-mediated transcriptional activation of CYP3A4, a gene involved in the metabolism of a wide range of drugs Tirona et al. 2003. At least four isoforms (HNF4 alpha1/HNF4B, HNF4 alpha2/HNF4A, HNF4 alpha3/HNF4C, and HNF4 alpha4) are produced by alternative splicing.

Gene Name: hepatocyte nuclear factor 4, alpha
Family/Subfamily: NHR , NR2 Hepatocyte NF4-like
Synonyms: HNF4A, Hepatic nuclear factor 4 alpha, HNF4, HNF4a8, NR2A21, TCF, TCF-14, TCF14, MODY1, Transcription factor 14, Transcription factor HNF-4, HNF-4-alpha, HNF4 alpha, HNF4a7, HNF4a9, HNF4alpha, HNF4alpha10/11/12, MODY, NR2A1
Target Sequences: NM_000457 NP_000448.3 P41235

Filtered By: None
Target
hnf4a-hnf4 (74)
Reactivity
Human (73)
Mouse (34)
Rat (26)
Bat (9)
Bovine (10)
Chicken (4)
Chimpanzee (6)
Dog (9)
Gibbon (9)
Guinea pig (8)
Hamster (9)
Horse (9)
Monkey (15)
Pig (11)
Rabbit (9)
Sheep (8)
Application
IHC (31)
IHC-P (16)
WB (71)
Flo (1)
ELISA (18)
ICC (4)
IF (10)
IP (1)
Peptide-ELISA (4)
RNAi (1)
Host
rabbit (67)
mouse (6)
goat (1)
Isotype
IgG (37)
IgG1 (4)
IgG2a (1)
IgG2a,k (1)
Clonality
monoclonal mc (6)
polyclonal pc (68)
Clone
2C10 (1)
2H2 (1)
4E2 (1)
5A9 (1)
8B8 (1)
9H8 (1)
Format
AP Conjugated (2)
APC (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (8)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (8)
HRP Conjugated (7)
PE Conjugated (3)
Unconjugated (41)
Epitope
aa131-330 (10)
Ser142 (8)
aa1-315 (5)
pSer313 (5)
C-Terminus (4)
N-Terminus (4)
aa252-301 (4)
Internal (2)
pSer304 (2)
Lys298 (1)
aa107-139 (1)
aa164-474 (1)
aa2-15 (1)
aa250-330 (1)
aa258-307 (1)
aa280-329 (1)
aa281-312 (1)
Publications
No (73)
Yes (1)
Showing 1-25 out of 74 results
HNF4A / HNF4 Antibody (N-Terminus) IHC-plus™ LS-B969
Anti-HNF4A / HNF4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B969 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Liver Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HNF4A / HNF4
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC IHC-P WB
Unconjugated
HNF4A / HNF4 Antibody (N-Terminus, HRP) LS-C427089
Anti-HNF4A / HNF4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B969 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Liver Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HNF4A / HNF4
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey
IHC IHC-P WB
HRP Conjugated
HNF4A / HNF4 Antibody (N-Terminus, Biotin) LS-C427087
Anti-HNF4A / HNF4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B969 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Liver Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HNF4A / HNF4
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey
IHC IHC-P WB
Biotin Conjugated
HNF4A / HNF4 Antibody (N-Terminus, FITC) LS-C427088
Anti-HNF4A / HNF4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B969 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal Liver Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HNF4A / HNF4
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey
IHC IHC-P WB
FITC Conjugated
HNF4A / HNF4 Antibody (aa2-15) IHC-plus™ LS-B3005
Anti-HNF4A / HNF4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3005 concentration 2 ug/ml.
Antibody (0.1 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Goat Polyclonal to Human HNF4A / HNF4
Rabbit, Dog, Hamster, Pig, Horse, Bat, Human, Monkey
IHC IHC-P Peptide-ELISA WB
Unconjugated
HNF4A / HNF4 Antibody (C-Terminus) IHC-plus™ LS-B4568
Anti-HNF4A / HNF4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4568 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-HNF4A / HNF4 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4568 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HNF4A / HNF4
Human, Monkey
IHC IHC-P WB
Unconjugated
HNF4A / HNF4 Antibody (C-Terminus, HRP) LS-C428244
Anti-HNF4A / HNF4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4568 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-HNF4A / HNF4 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4568 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HNF4A / HNF4
Human, Monkey, Chimpanzee, Gibbon
IHC IHC-P WB
HRP Conjugated
HNF4A / HNF4 Antibody (C-Terminus, Biotin) LS-C428242
Anti-HNF4A / HNF4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4568 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-HNF4A / HNF4 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4568 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HNF4A / HNF4
Human, Monkey, Chimpanzee, Gibbon
IHC IHC-P WB
Biotin Conjugated
HNF4A / HNF4 Antibody (C-Terminus, FITC) LS-C428243
Anti-HNF4A / HNF4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4568 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-HNF4A / HNF4 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4568 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HNF4A / HNF4
Human, Monkey, Chimpanzee, Gibbon
IHC IHC-P WB
FITC Conjugated
HNF4A / HNF4 Antibody (aa281-312) LS-C97258
HNF4A Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of HNF4A Antibody with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).

Rabbit Polyclonal to Human HNF4A / HNF4
Rat, Human
Flo IF IHC IHC-P WB
Unconjugated
HNF4A / HNF4 Antibody (aa107-139) LS-C164947
Confocal immunofluorescence of HNF4A Antibody with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Western blot of HNF4A Antibody in 293 cell line lysates (35 ug/lane). HNF4A (arrow) was detected using the purified antibody.

Rabbit Polyclonal to Human HNF4A / HNF4
Human
IF WB
Unconjugated
HNF4A / HNF4 Antibody (phospho-Ser313) LS-C354006
Immunohistochemical analysis of HNF4 alpha (pS313) staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of HNF4 alpha (pS313) staining in SW480 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

Rabbit Polyclonal to Human HNF4A / HNF4
Mouse, Bovine, Rat, Pig, Human, Monkey
ICC IF IHC IHC-P WB
Unconjugated
HNF4A / HNF4 Antibody (Internal) LS-C413074
Immunohistochemical analysis of HNF4 alpha/gamma staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of HNF4 alpha/gamma staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

Rabbit Polyclonal to Human HNF4A / HNF4
Mouse, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
HNF4A / HNF4 Antibody (clone 4E2) LS-C197427
Immunofluorescence of monoclonal antibody to HNF4A on HeLa cell. [antibody concentration 10 ug/ml]
HNF4A monoclonal antibody (M04), clone 4E2 Western Blot analysis of HNF4A expression in HepG2.

Mouse Monoclonal [clone 4E2] (IgG2a,k) to Human HNF4A / HNF4
Human
ELISA IF RNAi WB
Unconjugated
HNF4A / HNF4 Antibody (phospho-Ser313) LS-C416671
Western blot of HNF4 alpha phosphorylation expression in EGF treated HUVEC whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Rabbit Polyclonal to Human HNF4A / HNF4
Mouse, Rat, Human
ICC IF IHC WB
Unconjugated
HNF4A / HNF4 Antibody (phospho-Ser313) LS-C117375
IHC of paraffin-embedded human liver carcinoma, using HNF4 alpha (Phospho-Ser313) Antibody. The picture on the right is treated with the synthesized peptide.
Immunofluorescence of LOVO cells, using HNF4 alpha (Phospho-Ser313) Antibody. The picture on the right is treated with the synthesized peptide.

Rabbit Polyclonal (IgG) to Human HNF4A / HNF4
Mouse, Rat, Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
HNF4A / HNF4 Antibody (phospho-Ser313) LS-C381547
Western blot of Phospho-HNF4-alpha (S313) antibody

Rabbit Polyclonal (IgG) to Human HNF4A / HNF4
Mouse, Rat, Human
ELISA IF IHC WB
Unconjugated
HNF4A / HNF4 Antibody (aa164-474) LS-C344069
HNF-4-alpha antibody IHC-paraffin: Rat Kidney Tissue.
HNF-4-alpha antibody IHC-paraffin: Mouse Kidney Tissue.

Rabbit Polyclonal to Human HNF4A / HNF4
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
HNF4A / HNF4 Antibody LS-C486998

Rabbit Polyclonal to Human HNF4A / HNF4
Human
ICC IF WB
Unconjugated
HNF4A / HNF4 Antibody LS-C331883
Immunofluorescence analysis.
Western blot analysis of extracts of various cell lines.

Rabbit Polyclonal (IgG) to Human HNF4A / HNF4
Mouse, Rat, Human
IF IHC WB
Unconjugated
HNF4A / HNF4 Antibody (aa250-330) LS-C383969
Western blot of HNF-4alpha antibody

Rabbit Polyclonal (IgG) to Human HNF4A / HNF4
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
HNF4A / HNF4 Antibody (aa1-315, clone 2H2) LS-C340017
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-HNF4A mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HNF4A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HNF4A.

Mouse Monoclonal [clone 2H2] (IgG1) to Human HNF4A / HNF4
Human
IHC IHC-P WB
Unconjugated
HNF4A / HNF4 Antibody (Internal) LS-C413423
Immunohistochemical analysis of HNF4 alpha staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of HNF4 alpha expression in HT29 (A); rat muscle (B) whole cell lysates.

Rabbit Polyclonal to Human HNF4A / HNF4
Mouse, Bovine, Rat, Pig, Human, Monkey
IHC IHC-P WB
Unconjugated
HNF4A / HNF4 Antibody (phospho-Ser313) LS-C192225

Rabbit Polyclonal to Human HNF4A / HNF4
Mouse, Rat, Human
IHC WB
Unconjugated
HNF4A / HNF4 Antibody (Lys298) LS-C177317
Western blot of HNF4 (K298) pAb in extracts from HT-29 cells.

Rabbit Polyclonal to Human HNF4A / HNF4
Mouse, Rat, Human
IHC WB
Unconjugated

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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