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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HLA-E

major histocompatibility complex, class I, E heavy chain

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Gene Name: major histocompatibility complex, class I, E heavy chain
Synonyms: HLA-E, EA2.1, HLAE, MHC HLA-E alpha-2.1, MHC HLA-E alpha-1, EA1.2, HLA-6.2, MHC class I antigen E, QA1
Target Sequences: NM_005516 NP_005507.3 P13747

Filtered by: None
Target
HLA-E (68)
Reactivity
Human (68)
Mouse (4)
Rat (4)
Chimpanzee (3)
Non-Human Primate (2)
Non-Human Primates (2)
Orangutan (3)
Application
IHC (7)
IHC-Fr (1)
IHC-P (8)
WB (53)
Flo (15)
ELISA (14)
IP (10)
Host
rabbit (43)
mouse (25)
Isotype
IgG (25)
IgG1 (24)
Clonality
monoclonal mc (24)
polyclonal pc (44)
Clone
3D12HLA-E (2)
4D12 (1)
MEM-E/02 (5)
MEM-E/06 (3)
MEM-E/07 (4)
MEM-E/08 (2)
Format
AP Conjugated (3)
APC (1)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (9)
Concentrated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (5)
Unconjugated (32)
Epitope
aa108-135 (8)
aa136-350 (8)
C-Terminus (4)
aa158-207 (4)
aa22-305 (4)
Publications
No (68)
Showing 1-25 of 68 results

IHC-plus™ HLA-E Antibody (clone MEM-E/07) LS-B3730
Mouse Monoclonal [clone MEM-E/07] (IgG1) to Human HLA-E
Human
Flo, IHC, IHC-P, IP
Unconjugated
0.05mg  $425.00
Anti-HLA-E antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

HLA-E Antibody (clone MEM-E/07, Biotin) LS-C112626
Mouse Monoclonal [clone MEM-E/07] (IgG1) to Human HLA-E
Human
Flo, IHC-P, IP
Biotin Conjugated
0.1mg 1mg/ml  $345.00
Surface staining of HLA-E transfectants with anti-HLA-E (clone MEM-E/07) biotin, streptavidin-APC.

IHC-plus™ HLA-E Antibody (clone MEM-E/02) LS-B2857
Mouse Monoclonal [clone MEM-E/02] (IgG1) to Human HLA-E
Human, Non-Human Primates
IHC, IHC-P, WB
Unconjugated
0.05mg 1mg/ml  $425.00
Anti-HLA-E antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

HLA-E Antibody (clone 4D12) LS-C179742
Mouse Monoclonal [clone 4D12] (IgG1) to Human HLA-E
Human
Flo, IHC, IHC-Fr
Unconjugated
100µl 1mg/ml  $355.00
Flow Cytometry Image

HLA-E Antibody (clone 3D12HLA-E) LS-C106800
Mouse Monoclonal [clone 3D12HLA-E] (IgG1) to Human HLA-E
Human
Flo, IP, WB
Unconjugated
25µg  $245.00; 100µg 0.5mg/ml  $305.00
Staining of normal human peripheral blood cells with 0.5 ug of Purified Mouse IgG1, K isotype control (open histogram) or 0.5 ug of Purified anti-human HLA-E (3D12HLA-E) (colored histogram) followed by Biotin Anti-Mouse IgG and SAv-PE. Cells in the lymphocyte gate were used for analysis.

HLA-E Antibody (clone 3D12HLA-E, PE) LS-C106985
Mouse Monoclonal [clone 3D12HLA-E] (IgG1) to Human HLA-E
Human
Flo
PE Conjugated
25tst  $275.00; 100tst  $395.00
Staining of normal human peripheral blood cells with FITC anti-human HLA-ABC (W6/32) (LS-C106350) and 0.5 ug of PE Mouse IgG1, K isotype control (left) or PE anti-human HLA-E (3D12HLA-E) (right). Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ HLA-E Antibody (clone MEM-E/06) LS-B3729
Mouse Monoclonal [clone MEM-E/06] (IgG1) to Human HLA-E
Human, Non-Human Primates
Flo, IHC, IHC-P, IP
Unconjugated
0.05mg  $425.00
Anti-HLA-E antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

HLA-E Antibody (clone MEM-E/08) LS-C46065
Mouse Monoclonal [clone MEM-E/08] (IgG1) to Human HLA-E
Human
Flo, IP
Unconjugated
0.1mg 1mg/ml  $280.00

IHC-plus™ HLA-E Antibody (clone MEM-E/02, Concentrated) LS-B12810
Mouse Monoclonal [clone MEM-E/02] (IgG1) to Human HLA-E
Human
IHC, IHC-P, WB
Unconjugated, Concentrated
50µg 1mg/ml  $505.00
Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

HLA-E Antibody (clone MEM-E/02) LS-C179648
Mouse Monoclonal [clone MEM-E/02] (IgG1) to Human HLA-E
Human
IHC, WB
Unconjugated
100µg 1mg/ml  $355.00
Western blot Image

HLA-E Antibody (aa108-135) LS-C327580
Rabbit Polyclonal (IgG) to Human HLA-E
Human
ELISA, WB
Unconjugated
200µl  $590.00

HLA-E Antibody (aa108-135, Azide-free, HRP) LS-C278167
Rabbit Polyclonal (IgG) to Human HLA-E
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

HLA-E Antibody (aa108-135, PE) LS-C278171
Rabbit Polyclonal (IgG) to Human HLA-E
Human
ELISA, WB
PE Conjugated
200µl  $740.00

HLA-E Antibody (aa22-305) LS-C370920
Rabbit Polyclonal (IgG) to Human HLA-E
Human
ELISA
Unconjugated
50µg  $285.00; 100µg 2mg/ml  $385.00

HLA-E Antibody (aa158-207) LS-C146160
Rabbit Polyclonal to Human HLA-E
Human
WB
Unconjugated
100µl 0.5mg/ml  $365.00
HLA-E antibody Western blot of U937 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

HLA-E Antibody LS-C802558
Rabbit Polyclonal (IgG) to Human HLA-E
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

HLA-E Antibody LS-C37367
Mouse Monoclonal (IgG1) to Human HLA-E
Human
Flo, WB
Unconjugated
200µg  $755.00

HLA-E Antibody (Azide-free) LS-C37368
Mouse Monoclonal (IgG1) to Human HLA-E
Human
Flo, WB
Unconjugated, Azide-free
100µg  $545.00; 200µg  $1,005.00

HLA-E Antibody (clone MEM-E/06) LS-C759152
Mouse Monoclonal [clone MEM-E/06] (IgG1) to Human HLA-E
Human, Non-Human Primate
Flo, IHC-P, IP
Unconjugated
100µg  $365.00
HLA-E Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HLA-E Antibody (clone MEM-E/07) LS-C759203
Mouse Monoclonal [clone MEM-E/07] (IgG1) to Human HLA-E
Human
Flo, IHC-P, IP
Unconjugated
100µg  $405.00
HLA-E Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HLA-E Antibody (clone MEM-E/06, Concentrated) LS-C202182
Mouse Monoclonal [clone MEM-E/06] (IgG1) to Human HLA-E
Human
Flo, IP
Unconjugated, Concentrated
100µg  $485.00

HLA-E Antibody (clone MEM-E/08) LS-C759154
Mouse Monoclonal [clone MEM-E/08] (IgG1) to Human HLA-E
Human
Flo, IP
Unconjugated
100µg  $365.00

HLA-E Antibody LS-C780054
Rabbit Polyclonal to Human HLA-E
Human
ELISA, WB
Unconjugated
100µg 100µl 1mg/ml  $305.00

HLA-E Antibody LS-C752524
Rabbit Polyclonal (IgG) to Human HLA-E
Human
ELISA, WB
Unconjugated
100µg  $375.00

HLA-E Antibody (clone MEM-E/02) LS-C759219
Mouse Monoclonal [clone MEM-E/02] (IgG1) to Human HLA-E
Human, Non-Human Primate
IHC-P, WB
Unconjugated
100µg  $445.00
Showing 1-25 of 68 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).