Human HLA-E

Mouse

Human, Non-Human Primates (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

MEM-E/06

Unconjugated

Purified by protein-A affinity chromatography. Greater than 95% by SDS-PAGE.

Unmodified

Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide

The antibody MEM-E/06 recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.

• IHC
• IHC - Paraffin (10 µg/ml)
• Immunoprecipitation
• Flow Cytometry

PBS, pH 7.4, 15 mM Sodium Azide

Store at 2°C to 8°C. Do not freeze.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P13747 NCBI: NM_005516 NP_005507.3