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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FZD5 / Frizzled 5

frizzled class receptor 5

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Interacts specifically with Wnt5A to induce the beta-catenin pathway.

Gene Name: frizzled class receptor 5
Family/Subfamily: GPCR , Frizzled
Synonyms: FZD5, C2orf31, DKFZP434E2135, Frizzled family receptor 5, Fz5, Fzd-5, FzE5, Frizzled 5, Frizzled-5, Wnt receptor, Fz-5, HFZ5
Target Sequences: NM_003468 NP_003459.2 Q13467

Publications (1)

1
RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes. Johansson J, Naszai M, Hodder MC, Pickering KA, Miller BW, Ridgway RA, Yu Y, Peschard P, Brachmann S, Campbell AD, Cordero JB, Sansom OJ. Cell stem cell. 2019 April;24:592-607. [Full Text Article] [PubMed:30853556] [PMC:PMC6459002] Related Antibodies: LS-A4273.

Filtered by: None
Target
FZD5 / Frizzled 5 (66)
Reactivity
Human (66)
Mouse (26)
Rat (23)
Bovine (11)
Dog (7)
Hamster (7)
Monkey (7)
Pig (7)
Rabbit (7)
Application
IHC (31)
IHC-P (28)
WB (44)
Flo (3)
ELISA (20)
IF (5)
IP (1)
Peptide-ELISA (2)
Host
rabbit (61)
mouse (4)
goat (1)
Isotype
IgG (34)
IgG1 (3)
IgG2a,k (1)
Clonality
monoclonal mc (4)
polyclonal pc (62)
Clone
2D12 (2)
6A3 (1)
Format
AP Conjugated (6)
APC Conjugated (6)
Azide-free (4)
Biotin Conjugated (8)
FITC Conjugated (8)
HRP Conjugated (8)
PE Conjugated (6)
Unconjugated (24)
Epitope
N-Terminus (14)
aa472-500 (8)
Cytoplasmic Domain (7)
C-Terminus (5)
aa467-516 (4)
aa564-585 (2)
440-520 aa, C-terminal (1)
Amino Acid: 151-217 (1)
Tyr500 (1)
aa31-80 (1)
aa461-510 (1)
Publications
No (65)
Yes (1)
Showing 1-25 of 66 results

IHC-plus™ FZD5 / Frizzled 5 Antibody (N-Terminus) LS-A4273
Publications (1)
Publications (1)
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas and carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (N-Terminus, Biotin) LS-A105073
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas and carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (N-Terminus, FITC) LS-A105074
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas and carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (N-Terminus, Azide-free, HRP) LS-A105075
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas and carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (N-Terminus, PE) LS-A105076
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas and carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (N-Terminus, AP) LS-A105071
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas and carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (N-Terminus, APC) LS-A105072
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas and carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (aa461-510) LS-B10487
Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-FZD5 / Frizzled 5 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-FZD5 / Frizzled 5 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (N-Terminus) LS-A4278
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Rabbit, Dog, Bovine, Pig, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FZD5 / Frizzled 5 Antibody (C-Terminus) LS-C30356
Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Mouse, Human
WB
Unconjugated
100µl 0.5mg/ml  $385.00
A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

FZD5 / Frizzled 5 Antibody (clone 2D12) LS-C169125
Mouse Monoclonal [clone 2D12] (IgG1) to Human FZD5 / Frizzled 5
Human
ELISA, Flo, WB
Unconjugated
100µg 1mg/ml  $365.00
Western blot using FZD5 monoclonal antibody against human FZD5 recombinant protein. (Expected MW is 32.5 kDa)
Western blot using FZD5 mouse monoclonal antibody against A549 (1), and PC-3 (2) cell lysate.

IHC-plus™ FZD5 / Frizzled 5 Antibody (Cytoplasmic Domain) LS-A4284
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (Cytoplasmic Domain, APC) LS-A105090
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (Cytoplasmic Domain, AP) LS-A105089
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ FZD5 / Frizzled 5 Antibody (Cytoplasmic Domain, Azide-free, HRP) LS-A105093
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FZD5 / Frizzled 5 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

FZD5 / Frizzled 5 Antibody (440-520 aa, C-terminal) LS-C383568
Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

IHC-plus™ FZD5 / Frizzled 5 Antibody (aa467-516) LS-B5722
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl  $485.00
Anti-FZD5 / Frizzled 5 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
FZD5 / Frizzled 5 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

FZD5 / Frizzled 5 Antibody (aa467-516, Biotin) LS-C441843
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Anti-FZD5 / Frizzled 5 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
FZD5 / Frizzled 5 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ FZD5 / Frizzled 5 Antibody (aa31-80) LS-B12542
Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
100µl 1mg/ml  $505.00
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)

FZD5 / Frizzled 5 Antibody LS-C6908
Goat Polyclonal (IgG) to Human FZD5 / Frizzled 5
Human
ELISA, WB
Unconjugated
100µg  $785.00

FZD5 / Frizzled 5 Antibody (aa472-500, Biotin) LS-C214425
Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

FZD5 / Frizzled 5 Antibody (aa564-585) LS-C23726
Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Human
WB
Unconjugated
200µg  $620.00

FZD5 / Frizzled 5 Antibody (aa564-585) LS-C152730
Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Human
WB
Unconjugated
200µg 1mg/ml  $415.00
WB: TENT lysates of transiently transfected 293 cells were probed with anti-Frizzled 5 (1g/ml).

FZD5 / Frizzled 5 Antibody LS-C496887
Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50µl  $265.00; 100µl  $345.00

FZD5 / Frizzled 5 Antibody (Tyr500) LS-C177200
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µl  $345.00
Western blot of Frizzled-5 (Y500) pAb in extracts from LOVO cells.
Showing 1-25 of 66 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).