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FGF2 / Basic FGF

fibroblast growth factor 2 (basic)

FGF2 / Basic FGF is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Gene Name: fibroblast growth factor 2 (basic)
Family/Subfamily: HBGF , not assigned-HBGF
Synonyms: FGF2, Basic fibroblast growth factor, FGFB, Fibroblast growth factor 2, FGF-2, Prostatropin, BFGF, HBGF-2
Target Sequences: NM_002006 NP_001997.5 P09038

Publications (1)

1
A phase Ib study of GSK3052230, an FGF ligand trap in combination with pemetrexed and cisplatin in patients with malignant pleural mesothelioma10<sup> Washington University School of Medicine, St. Louis, MO, USA12<sup> Memorial Sloan Kettering Cancer Center, New York, NY, USA14<sup> GlaxoSmithKline, Inc., 1250 South Collegeville Road, Collegeville, PA, USA16<sup> Utrecht University, Utrecht, The Netherlands18<sup> Phase I Trials Unit, Medical Oncology Department, Hospital Universitario Virgen de. Emilie M J van Brummelen, Evgeny Levchenko, Manuel Dómine, Dean A Fennell, Hedy L Kindler, Santiago Viteri, Shirish Gadgeel, Pilar Garrido López, Vladimir Kostorov, Daniel Morgensztern, Sergey Orlov, Marjorie G Zauderer, Johan F Vansteenkiste, Katherine Baker-Neblett, James Vasquez, Xiaowei Wang, David I Bellovin, Jan H M Schellens, Li Yan, Ionel Mitrica, M Phillip DeYoung, José Trigo. Investigational new drugs. 2020 Apr;;38:457-467. [Full Text Article] [PubMed:31065954] [PMC:PMC6898757] Related Antibodies: LS-B10042.

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Antibodies (114)
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FGF2 / Basic FGF (222)
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FGF2 / Basic FGF Antibody - Anti-FGF2 / Basic FGF antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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FGF2 / Basic FGF Mouse anti-Human Monoclonal (3D9) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$440
FGF2 / Basic FGF Antibody - Anti-FGF2 / BFGF antibody IHC of human breast, myoepithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
FGF2 / Basic FGF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FGF2 / Basic FGF Antibody - Immunohistochemistry of paraffin-embedded human prostate using.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Neuroscience
FGF2 / Basic FGF Rabbit anti-Human Polyclonal (aa 143-288) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FGF2 / Basic FGF Antibody - Immunohistochemistry of paraffin-embedded human prostate using.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FGF2 / Basic FGF Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
FGF2 / Basic FGF Antibody - Immunohistochemistry of paraffin-embedded human prostate using.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FGF2 / Basic FGF Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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FGF2 / Basic FGF Mouse anti-Bovine Monoclonal Antibody
Mouse, Bovine, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$463; 500 µg/$925
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FGF2 / Basic FGF Rabbit anti-Bovine Polyclonal Antibody
Bovine, Pig, Human
IHC, RIA, WB
Unconjugated
20 µl/$488; 100 µl/$957
FGF2 / Basic FGF Antibody - Western blot All lanes: Heparin-binding growth factor 2 antibody at 2µg/ml Lane 1: EC109 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 32 kDa Observed band size: 32 kDa
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FGF2 / Basic FGF Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Microplate
Pig
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
FGF2 / Basic FGF Protein - Recombinant Fibroblast Growth Factor 2, Basic By SDS-PAGE
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E. coli
His
16.2 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
FGF2 / Basic FGF ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
FGF2 / Basic FGF Antibody - FGF2 antibody Western blot. All lanes: Anti FGF2 at 0.5 ug/ml. Lane 1: Human Placenta Tissue Lysate at 50 ug. Lane 2: Rat Brain Tissue Lysate at 50 ug. Lane 3: Rat Kidney Tissue Lysate at 50 ug. Lane 4: Rat Spleen Tissue Lysate at 50 ug. Predicted band size: 17 kD. Observed band size: 17 kD.
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FGF2 / Basic FGF Rabbit anti-Human Polyclonal (aa219-249) Antibody
Rat, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
FGF2 / Basic FGF Protein
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E. coli
His, N-Terminal
17 kDa
10 µg/$265; 100 µg/$365; 50 µg/$315
FGF2 / Basic FGF Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BFGF (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BFGF.
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FGF2 / Basic FGF Mouse anti-Human Monoclonal (OTI3D10) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
FGF2 / Basic FGF ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
63 - 400 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$414
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$760
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
FGF2 / Basic FGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$590
FGF2 / Basic FGF ELISA Kit
Select
Sandwich
96-Well Microplate
Bovine
4.1 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$610
FGF2 / Basic FGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
FGF2 / Basic FGF Antibody - IHC of paraffin- embedded human recturn adenocarcinoma tissue showing cytoplasmic localization using FGF2 mouse mAb with DAB staining.
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FGF2 / Basic FGF Mouse anti-Human Monoclonal (2H5G2C11) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 ml/$380
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FGF2 / Basic FGF Mouse anti-Bovine Monoclonal Antibody
Bovine, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
500 µg/$1,042
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FGF2 / Basic FGF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
FGF2 / Basic FGF Antibody - Western blot of recombinant FGF2 / Basic FGF.
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FGF2 / Basic FGF Rabbit anti-Mouse Polyclonal (aa10-154) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
Viewing 1-25 of 222 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).