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FCGR3A / CD16A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

FCGR3A / CD16A is a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Synonyms: FCGR3A, CD16A, CD16a antigen, CD16, FcgammaRIIIA, FCR-10, FCRIII, Fc gamma receptor III-A, Fc-gamma RIII, Fc-gamma RIII-alpha, FCG3, IGFR3, Fc- gamma riii, Fc-gamma receptor IIIb (CD16), Fc-gamma RIIIa, FCGR3, FCRIIIA, Neutrophil-specific antigen NA, Igg fc receptor iii-1, IgG Fc receptor III-2, Igg fc receptors iii-1, FCGRIII
Target Sequences: NM_000569 NP_000560.5 P08637

Publications (1)

1
In Vitro Exposure to Prostratin but Not Bryostatin-1 Improves Natural Killer Cell Functions Including Killing of CD4+ T Cells Harboring Reactivated Human Immunodeficiency Virus. Desimio MG, Giuliani E, Ferraro AS, Adorno G, Doria M. Frontiers in immunology. 2018 June;9: [Full Text Article] [PubMed:30008723] [PMC:PMC6033996]

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FCGR3A / CD16A (82)
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41 (5)
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aa5-240 (8)
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No (82)
FCGR3A / CD16A Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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FCGR3A / CD16A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
FCGR3A / CD16A Mouse anti-Human Monoclonal (Azide-free) (MEM-154) Antibody
Human
Flo, Func, IP, WB
Unconjugated, Azide-free
0.1 mg/$302
Select
FCGR3A / CD16A Mouse anti-Human Monoclonal (MEM-154) Antibody
Human
Flo, Func, IP, WB
Unconjugated
0.1 mg/$302
Select
FCGR3A / CD16A Rabbit anti-Human Polyclonal (aa225-254) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
FCGR3A / CD16A Rabbit anti-Human Polyclonal (aa225-254) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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FCGR3A / CD16A Rabbit anti-Human Polyclonal (aa225-254) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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FCGR3A / CD16A Rabbit anti-Human Polyclonal (aa225-254) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
FCGR3A / CD16A Antibody - Surface staining of CD16 in human peripheral blood with anti-CD16 (3G8) purified / GAM-APC.
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FCGR3A / CD16A Mouse anti-Human Monoclonal (3G8) Antibody
Human, Non-Human Primates
Flo, Func, IHC, IHC-Fr, IP
Unconjugated
0.1 mg/$302
FCGR3A / CD16A Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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FCGR3A / CD16A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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FCGR3A / CD16A Mouse anti-Human Monoclonal (Biotin) (MEM-154) Antibody
Human
Flo, Func, IP, WB
Biotin Conjugated
0.1 mg/$337
FCGR3A / CD16A Antibody - Western Blot; Sample: Recombinant FcgR3A, Rat.
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FCGR3A / CD16A Rabbit anti-Rat Polyclonal (aa5-241) Antibody
Rat
WB
Unconjugated
100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268
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FCGR3A / CD16A Mouse anti-Human Monoclonal (Low Endotoxin) (3G8) Antibody
Human, Non-Human Primates
Flo, Func, IHC-Fr, IP
Unconjugated, Low Endotoxin
0.1 mg/$302
FCGR3A / CD16A Antibody - Surface staining of human peripheral blood cells with anti-human CD16 (MEM-154) PE. The antibody MEM-154 does not react with CD16a present on NK cells in many subjects.
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FCGR3A / CD16A Mouse anti-Human Monoclonal (PE) (MEM-154) Antibody
Human
Flo, Func, IP, WB
PE Conjugated
100 Tests/$365
FCGR3A / CD16A Antibody - Western blot - Anti-CD16 Picoband antibody
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FCGR3A / CD16A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
FCGR3A / CD16A Mouse anti-Rat Monoclonal Antibody
Rat
ELISA
Unconjugated
100 µl/$412
Select
FCGR3A / CD16A Mouse anti-Human Monoclonal (N418) Antibody
Human, Monkey, Baboon, Cynomolgus, Marmoset
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$468
Select
FCGR3A / CD16A Mouse anti-Human Monoclonal (Low Endotoxin) (MEM-154) Antibody
Human
Flo, Func, IP, WB
Unconjugated, Low Endotoxin
0.1 mg/$302
Select
FCGR3A / CD16A Mouse anti-Human Monoclonal (2G10A9) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
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FCGR3A / CD16A Mouse anti-Human Monoclonal (FITC) (MEM-154) Antibody
Human
Flo, Func, IP, WB
FITC Conjugated
100 Tests/$337
FCGR3A / CD16A Antibody - 1:100 staining human urothelial carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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FCGR3A / CD16A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
FCGR3A / CD16A Mouse anti-Human Monoclonal (Biotin) (3G8) Antibody
Human, Non-Human Primates
Flo, Func, IHC-Fr, IP
Biotin Conjugated
0.1 mg/$337
Select
FCGR3A / CD16A Mouse anti-Human Monoclonal (APC) (3G8) Antibody
Human, Non-Human Primates
Flo, Func, IHC-Fr, IP
APC Conjugated
100 Tests/$365
Select
FCGR3A / CD16A Mouse anti-Human Monoclonal (FITC) (3G8) Antibody
Human, Non-Human Primates
Flo, Func, IHC-Fr, IP
FITC Conjugated
100 Tests/$337
FCGR3A / CD16A Antibody - Immunohistochemical analysis of CD16 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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FCGR3A / CD16A Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
FCGR3A / CD16A Antibody - Surface staining of CD16 in human peripheral blood with anti-CD16 (3G8) PerCP.
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FCGR3A / CD16A Mouse anti-Human Monoclonal (PerCP) (3G8) Antibody
Human, Non-Human Primates
Flo, Func, IHC-Fr, IP
PerCP Conjugated
100 Tests/$365
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).