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ESRRG / ERR Gamma

estrogen-related receptor gamma

ESRRG / ERR Gamma is a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region.

Gene Name: estrogen-related receptor gamma
Family/Subfamily: NHR , NR3 Steroid receptor
Synonyms: ESRRG, ERR Gamma, ERR gamma-2, ERR3, Err-gamma, NR3B3, ERRG2, ERRgamma, KIAA0832
Target Sequences: NM_001438 NP_001429.2 P62508

Publications (2)

1
Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression. Zhang Y, Ma K, Sadana P, Chowdhury F, Gaillard S, Wang F, McDonnell DP, Unterman TG, Elam MB, Park EA. The Journal of biological chemistry. 2006 281:39897-906. (WB, ChrIP; Rat) [PubMed:17079227] Related Antibodies: LS-A5960.
2
Expression of estrogen-related receptor gamma (ERRgamma) in human skin. Krahn-Bertil E, Bolzinger MA, Andre V, Orly I, Kanitakis J, Rousselle P, Damour O. European journal of dermatology : EJD. 18:427-32. (IHC-P; Human) [PubMed:18573717] Related Antibodies: LS-A5960.

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ESRRG / ERR Gamma (47)
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ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
ChrIP, IHC, IHC-P, WB
Unconjugated
50 µg/$440
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ESRRG / ERR Gamma Antibody - ESRRG / ERR3 antibody ARP31655_T100-NP_996318-ESRRG (estrogen-related receptor gamma) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (aa190-239) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
ESRRG / ERR Gamma Antibody - ESRRG / ERR3 antibody ARP31655_T100-NP_996318-ESRRG (estrogen-related receptor gamma) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (aa190-239) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Gibbon, Orangutan, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
ESRRG / ERR Gamma Antibody - ESRRG / ERR3 antibody ARP31655_T100-NP_996318-ESRRG (estrogen-related receptor gamma) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (aa190-239) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Gibbon, Orangutan, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
ESRRG / ERR Gamma Antibody - ESRRG / ERR3 antibody ARP31655_T100-NP_996318-ESRRG (estrogen-related receptor gamma) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (aa190-239) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Gibbon, Orangutan, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
ESRRG / ERR Gamma Antibody - Anti-ESRRG mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ESRRG.
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ESRRG / ERR Gamma Mouse anti-Human Monoclonal (OTI1D10) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
ESRRG / ERR Gamma Antibody - Anti-ESRRG mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ESRRG.
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ESRRG / ERR Gamma Mouse anti-Human Monoclonal (aa24-263) (Carrier-free) (OTI1D10) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
Fast Shipping
ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Xenopus, Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
ESRRG / ERR Gamma Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ESRRG mouse monoclonal antibody.
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ESRRG / ERR Gamma Mouse anti-Human Monoclonal (OTI6G1) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
ESRRG / ERR Gamma Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-ESRRG mouse monoclonal antibody.
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ESRRG / ERR Gamma Mouse anti-Human Monoclonal (aa24-263) (Carrier-free) (OTI6G1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ESRRG / ERR Gamma Antibody - Immunohistochemistry - Anti-ESRRG Picoband antibody
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ESRRG / ERR Gamma Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ESRRG / ERR Gamma Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ESRRG / ERR Gamma Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ESRRG / ERR Gamma Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Orangutan, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ESRRG / ERR Gamma Antibody - IHC of paraffin-embedded Human breast tissue using anti-ESRRG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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ESRRG / ERR Gamma Mouse anti-Human Monoclonal (aa24-263) (OTI1E5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
ESRRG / ERR Gamma Antibody - IHC of paraffin-embedded Human breast tissue using anti-ESRRG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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ESRRG / ERR Gamma Mouse anti-Human Monoclonal (aa24-263) (Carrier-free) (OTI1E5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ESRRG / ERR Gamma Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using ESRRG Polyclonal Antibody at dilution of 1:30.
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ESRRG / ERR Gamma Antibody - Anti-ESRRG mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ESRRG.
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ESRRG / ERR Gamma Mouse anti-Human Monoclonal (aa24-263) (OTI5G8) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
ESRRG / ERR Gamma Antibody - Anti-ESRRG mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ESRRG.
Select
ESRRG / ERR Gamma Mouse anti-Human Monoclonal (aa24-263) (Carrier-free) (OTI5G8) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
ESRRG / ERR Gamma Antibody - Western blot analysis of extracts of human kidney tissue using ESRRG antibody. The lane on the left was treated with blocking peptide.
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ESRRG / ERR Gamma Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).