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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ESRRG / ERR Gamma

estrogen-related receptor gamma

ESRRG / ERR Gamma is a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region.

Gene Name: estrogen-related receptor gamma
Family/Subfamily: NHR , NR3 Steroid receptor
Synonyms: ESRRG, ERR Gamma, ERR gamma-2, ERR3, Err-gamma, NR3B3, ERRG2, ERRgamma, KIAA0832
Target Sequences: NM_001438 NP_001429.2 P62508

Publications (2)

1
Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression. Zhang Y, Ma K, Sadana P, Chowdhury F, Gaillard S, Wang F, McDonnell DP, Unterman TG, Elam MB, Park EA. The Journal of biological chemistry. 2006 281:39897-906. (WB, ChrIP; Rat) [PubMed:17079227] Related Antibodies: LS-A5960.
2
Expression of estrogen-related receptor gamma (ERRgamma) in human skin. Krahn-Bertil E, Bolzinger MA, Andre V, Orly I, Kanitakis J, Rousselle P, Damour O. European journal of dermatology : EJD. 18:427-32. (IHC-P; Human) [PubMed:18573717] Related Antibodies: LS-A5960.

Viewing 1-25 of 71 items
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
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Rabbit Polyclonal to Human ESRRG / ERR Gamma
Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
ChrIP, IHC, IHC-P, WB
Unconjugated
50µg   50µl   1mg/ml   $425.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
ChrIP, IHC, IHC-P, WB
Biotin Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
ChrIP, IHC, IHC-P, WB
FITC Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
ChrIP, IHC, IHC-P, WB
HRP Conjugated, Azide-free
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
ChrIP, IHC, IHC-P, WB
PE Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
ChrIP, IHC, IHC-P, WB
APC Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
ChrIP, IHC, IHC-P, WB
AP Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Cancer
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Xenopus, Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Xenopus, Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Xenopus, Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Xenopus, Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Xenopus, Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Xenopus, Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Xenopus, Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
Biotin Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
FITC Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
AP Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
APC Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
ELISA, IHC, IHC-P
PE Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human ESRRG / ERR Gamma
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
ESRRG / ERR Gamma Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human ESRRG / ERR Gamma
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   $485.00

Viewing 1-25 of 71 items


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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).