Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-A5960-50 50 µg (1 mg/ml) $440 
ESRRG / ERR Gamma Antibody - Breast, Carcinoma
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ESRRG / ERR Gamma Antibody - Ovary, carcinoma
ESRRG / ERR Gamma Antibody - Lung, Non Small-Cell Carcinoma
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney, diabetes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human breast cancer. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ESRRG / ERR Gamma Antibody - Ovary, Carcinoma
ESRRG / ERR Gamma Antibody - Breast, Carcinoma
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ESRRG / ERR Gamma Antibody - Ovary, carcinoma
ESRRG / ERR Gamma Antibody - Lung, Non Small-Cell Carcinoma
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney, diabetes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human breast cancer. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ESRRG / ERR Gamma Antibody - Ovary, Carcinoma
1 of 9
2 of 9
3 of 9
4 of 9
5 of 9
6 of 9
7 of 9
8 of 9
9 of 9

PathPlus™ Polyclonal Rabbit anti‑Human ESRRG / ERR Gamma Antibody (C‑Terminus, IHC, WB) LS‑A5960

PathPlus™ Polyclonal Rabbit anti‑Human ESRRG / ERR Gamma Antibody (C‑Terminus, IHC, WB) LS‑A5960

Antibody:
ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, WB, ChrIP
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-A5960-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ESRRG / ERR Gamma Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, WB, ChrIP
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Format:
Unconjugated, Unmodified

Specifications

Description
ESRRG / ERR Gamma is a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human ESRRG / ERR Gamma
Synonyms
ESRRG | ERR Gamma | ERR gamma-2 | ERR3 | Err-gamma | NR3B3 | ERRG2 | ERRgamma | KIAA0832
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Predicted
Bat, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 15 amino acid peptide from C-Terminus of human ESRRG / ERR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard (100%); Bat, Xenopus, Zebrafish (93%); Stickleback, Medaka, Pufferfish (87%).
Epitope
C-Terminus
Specificity
Human ESRRG / ERR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (9 - 17 µg/ml)
  • Western blot
  • Chromatin Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ESRRG / ERR Gamma
P62508 NM_001438 NP_001429.2

Validation

ESRRG / ERR Gamma Antibody - Breast, Carcinoma
Breast, Carcinoma
Breast, Carcinoma

ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ESRRG / ERR Gamma antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ESRRG / ERR Gamma antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ESRRG / ERR Gamma Antibody - Ovary, carcinoma
Ovary, carcinoma
Ovary, carcinoma

ESRRG / ERR Gamma Antibody - Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma

ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney, diabetes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ESRRG / ERR Gamma antibody IHC of human kidney, diabetes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ESRRG / ERR Gamma antibody IHC of human kidney, diabetes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR3 antibody IHC of human breast cancer. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ESRRG / ERR3 antibody IHC of human breast cancer. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ESRRG / ERR3 antibody IHC of human breast cancer. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ESRRG / ERR Gamma antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ESRRG / ERR Gamma Antibody - Anti-ESRRG / ERR Gamma antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ESRRG / ERR Gamma antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ESRRG / ERR Gamma antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ESRRG / ERR Gamma Antibody - Ovary, Carcinoma
Ovary, Carcinoma
Ovary, Carcinoma

LSBio Ratings

PathPlus™ ESRRG / ERR Gamma Antibody (C-Terminus) for IHC, WB/Western LS-A5960 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (5)

Publications (2)

Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression. Zhang Y, Ma K, Sadana P, Chowdhury F, Gaillard S, Wang F, McDonnell DP, Unterman TG, Elam MB, Park EA. The Journal of biological chemistry. 2006 281:39897-906. (WB, ChrIP; Rat)

Expression of estrogen-related receptor gamma (ERRgamma) in human skin. Krahn-Bertil E, Bolzinger MA, Andre V, Orly I, Kanitakis J, Rousselle P, Damour O. European journal of dermatology : EJD. 18:427-32. (IHC-P; Human)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/21/2024