Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ELK3 / NET is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants.
|Gene Name:||ELK3, ETS-domain protein (SRF accessory protein 2)|
|Family/Subfamily:||Transcription factor , not assigned-Transcription factor|
|Synonyms:||ELK3, ERP, Ets-domain protein elk-3, ETS-related protein NET, ETS-domain protein, NET, SAP-2, SAP2, SRF accessory protein 2, ETS-related protein ERP|
|Target Sequences:||NM_005230 NP_005221.2 P41970|
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