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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EHMT2 / G9A

euchromatic histone-lysine N-methyltransferase 2

Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself.

Gene Name: euchromatic histone-lysine N-methyltransferase 2
Synonyms: EHMT2, BAT8, C6orf30, Em:AF134726.3, KMT1C, G9A, GAT8, H3-K9-HMTase 3, Protein G9a, G9A histone methyltransferase, HLA-B associated transcript 8, HLA-B-associated transcript 8, Lysine N-methyltransferase 1C, NG36
Target Sequences: NM_006709 NP_006700.3 Q96KQ7

Viewing 1-25 of 41 items
Select
Rabbit Monoclonal (IgG) to Human EHMT2 / G9A
Mouse, Rat, Human
IF, WB
Unconjugated
100µl   $530.00
EHMT2 / G9A Antibody
Select
Hamster Monoclonal [clone 14-1] (IgG) to Human EHMT2 / G9A
Mouse, Human
WB
Unconjugated
100µg   1mg/ml   $345.00
EHMT2 / G9A Antibody - Western blot of EHMT2 pAb in extracts from Jurkat, HEK-293 and Hela cells.
Select
Rabbit Polyclonal to Human EHMT2 / G9A
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl   $385.00
EHMT2 / G9A Antibody - EHMT2 / G9A antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human EHMT2 / G9A
Rabbit, Dog, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $385.00
EHMT2 / G9A Antibody - Detection of Human G9A/EHMT2 by Immunohistochemistry. Sample: FFPE section of human lung carcinoma. Antibody: Affinity purified rabbit anti-G9A/EHMT2 used at a dilution of 1:1000 (1 Detection: DAB.
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human
IHC, IP, WB
Unconjugated
100µl   1mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human
ELISA, Flo, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human
ELISA, Flo, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human
ELISA, Flo, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human
ELISA, Flo, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human
ELISA, Flo, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human
ELISA, Flo, WB
PE Conjugated
200µl   $740.00
EHMT2 / G9A Antibody
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
EHMT2 / G9A Antibody - Western blot of EHMT2 / G9A antibody LS-X223189.
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Mouse, Rat, Human
IHC, WB
Unconjugated
100µg   $465.00
EHMT2 / G9A Antibody - Western blot analysis of extracts of Mouse spleen tissue.
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Mouse, Rat, Human
IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
EHMT2 / G9A Antibody - EHMT2 Antibody western blot of Jurkat cell line lysates (15 ug/lane). The EHMT2 antibody detected the EHMT2 protein (arrow).
Select
Rabbit Polyclonal to Human EHMT2 / G9A
Human
Flo, WB
Unconjugated
400µl   $325.00
Select
Rabbit Polyclonal to Mouse EHMT2 / G9A
Human
Peptide-ELISA, WB
Unconjugated
400µl   $325.00
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human
ELISA, WB
Unconjugated
100µg   $335.00
Select
Rabbit Polyclonal to Human EHMT2 / G9A
Mouse, Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
EHMT2 / G9A Antibody - Anti-Ehmt2 Antibody at 1:1000 dilution + mouse brain lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 138 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
Rabbit Polyclonal to Mouse EHMT2 / G9A
Mouse
Peptide-ELISA, WB
Unconjugated
400µl   $325.00
EHMT2 / G9A Antibody - Western blot of lysates from HeLa, Jurkat, A431, mouse NIH/3T3 cell line (from left to right), using EHMT2 antibody diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.
Select
Rabbit Polyclonal to Human EHMT2 / G9A
Mouse, Human
Peptide-ELISA, WB
Unconjugated
400µl   $325.00
EHMT2 / G9A Antibody - Detection of Human G9A/EHMT2 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-G9A/EHMT2 used at a dilution of 1:100. Epitope Retrieval Buffer-High pH (IHC-101J) was substituted for Epitope Retrieval Buffer-Reduced pH.
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human
IHC
Unconjugated
100µl   $415.00
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Mouse, Rat, Human
WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human EHMT2 / G9A
Human, Monkey
WB
Unconjugated
200µg   $755.00
Select
Rabbit Polyclonal to Human EHMT2 / G9A
Mouse, Human
WB
Unconjugated
100µg   $635.00

Viewing 1-25 of 41 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).