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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DPYSL2 / CRMP2

dihydropyrimidinase-like 2

DPYSL2 / CRMP2 is a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: dihydropyrimidinase-like 2
Synonyms: DPYSL2, CRMP2, CRMP-2, DHPRP2, Dihydropyrimidinase-like 2, DRP-2, N2A3, ULIP2, ULIP-2, Unc-33-like phosphoprotein 2
Target Sequences: NM_001386 NP_001377.1 Q16555

Publications (2)

1
Glyoxalase 1-knockdown in human aortic endothelial cells - effect on the proteome and endothelial function estimates. Stratmann B, Engelbrecht B, Espelage BC, Klusmeier N, Tiemann J, Gawlowski T, Mattern Y, Eisenacher M, Meyer HE, Rabbani N, Thornalley PJ, Tschoepe D, Poschmann G, Stühler K. Scientific reports. 2016 6:37737. (WB; Human) [Full Text Article] [PubMed:27898103] [PMC:PMC5127188] Related Antibodies: LS-B3616.
2
PACAP stimulates functional recovery after spinal cord injury through axonal regeneration. Tsuchida M, Nakamachi T, Sugiyama K, Tsuchikawa D, Watanabe J, Hori M, Yoshikawa A, Imai N, Kagami N, Matkovits A, Atsumi T, Shioda S. Journal of molecular neuroscience : MN. Nov;54:380-7. [Full Text Article] [PubMed:25074795] Related Antibodies: LS-B5657.

Filtered by: None
Target
DPYSL2 / CRMP2 (51)
Reactivity
Human (51)
Mouse (38)
Rat (37)
Bat (4)
Bovine (6)
Chicken (2)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Hamster (4)
Horse (4)
Monkey (2)
Orangutan (3)
Pig (6)
Rabbit (4)
Zebrafish (4)
Application
IHC (24)
IHC-P (11)
WB (47)
Flo (1)
ELISA (20)
ICC (3)
IF (13)
IP (3)
Peptide-ELISA (5)
Host
rabbit (39)
mouse (11)
goat (1)
Isotype
IgG (29)
IgG1 (3)
IgG2a,k (1)
IgG2b (4)
IgG2b,k (1)
IgG3 (1)
Clonality
monoclonal mc (11)
polyclonal pc (40)
Clone
1F11 (1)
33CT11.40.3 (1)
3F4 (1)
C4G (1)
EPR7792 (1)
N3E (1)
OTI2C9 (2)
OTI5D7 (2)
Format
Biotin Conjugated (2)
Carrier-free (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (45)
Epitope
C-Terminus (6)
450-530 aa (4)
aa13-490 (4)
aa432-481 (4)
pThr514 (4)
460-540 aa (2)
aa463-492 (2)
Pro510 (1)
aa461-510 (1)
aa475-524 (1)
aa480-529 (1)
pSer465 (1)
pThr509 (1)
Publications
No (49)
Yes (2)
Showing 1-25 of 51 results

IHC-plus™ DPYSL2 / CRMP2 Antibody (aa480-529) LS-B5657
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-CRMP-2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-CRMP-2 antibody IHC of human colon, peripheral nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

IHC-plus™ DPYSL2 / CRMP2 Antibody (aa463-492, clone 33CT11.40.3) LS-B3616
Publications (1)
Publications (1)
Mouse Monoclonal [clone 33CT11.40.3] (IgG2b) to Human DPYSL2 / CRMP2
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200µl  $425.00
Anti-CRMP-2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-CRMP-2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

DPYSL2 / CRMP2 Antibody (clone 1F11) LS-C197078
Mouse Monoclonal [clone 1F11] (IgG2a,k) to Human DPYSL2 / CRMP2
Human
ELISA, IF, WB
Unconjugated
100µg  $365.00
Immunofluorescence of monoclonal antibody to DPYSL2 on HeLa cell . [antibody concentration 10 ug/ml]
Detection limit for recombinant GST tagged DPYSL2 is 0.03 ng/ml as a capture antibody.

IHC-plus™ DPYSL2 / CRMP2 Antibody (C-Terminus, clone EPR7792) LS-B9303
Rabbit Monoclonal [clone EPR7792] (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
50µl  $425.00
Anti-DPYSL2 / CRMP2 antibody IHC staining of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Western blot analysis on (A) PC-12, (B) Jurkat, (C) U87-MG, and (D) NIH/3T3 cell lysates using anti-CRMP-2 antibody.

DPYSL2 / CRMP2 Antibody (C-Terminus) LS-C42568
Goat Polyclonal (IgG) to Human DPYSL2 / CRMP2
Human
ELISA, WB
Unconjugated
100µl  $385.00

DPYSL2 / CRMP2 Antibody (phospho-Thr514) LS-C416830
Rabbit Polyclonal to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
100µg  $305.00
Western blot of DRP-2 phosphorylation expression in PMA treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

DPYSL2 / CRMP2 Antibody (clone 3F4) LS-C193571
Mouse Monoclonal [clone 3F4] (IgG3) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IHC, WB
Unconjugated
100µg 1ml  $890.00

DPYSL2 / CRMP2 Antibody LS-C672411
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image of paraffin-embedded human brain tissue at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human glioma cancer at a dilution of 1:100

DPYSL2 / CRMP2 Antibody (phospho-Thr514) LS-C801206
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Immunofluorescence Image

IHC-plus™ DPYSL2 / CRMP2 Antibody (aa475-524) LS-B12440
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100µl 1mg/ml  $505.00
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of lysates from HT-29 cells, treated with heat shock, using CRMP-2 Antibody. The lane on the right is blocked with the synthesized peptide.

IHC-plus™ DPYSL2 / CRMP2 Antibody (aa461-510) LS-B12485
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100µl 1mg/ml  $505.00
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

DPYSL2 / CRMP2 Antibody LS-C801655
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Immunofluorescence Image

DPYSL2 / CRMP2 Antibody LS-C417652
Rabbit Polyclonal to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
100µg  $305.00
Western blot of DRP-2 expression in EGF treated A549 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

DPYSL2 / CRMP2 Antibody LS-C664802
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Human
ELISA, IF, IHC, WB
Unconjugated
100µg  $335.00

DPYSL2 / CRMP2 Antibody (phospho-Thr514) LS-C198892
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain, using DRP-2 (Phospho-Thr514) Antibody. The picture on the right is blocked with the phospho peptide.
Immunofluorescence analysis of HeLa cells, using DRP-2 (Phospho-Thr514) Antibody. The picture on the right is blocked with the phospho peptide.

DPYSL2 / CRMP2 Antibody (450-530 aa) LS-C381538
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of Phospho-CRMP-2 (T514) antibody

DPYSL2 / CRMP2 Antibody (450-530 aa) LS-C382906
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of CRMP-2 antibody

DPYSL2 / CRMP2 Antibody (Pro510) LS-C177337
Rabbit Polyclonal to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl  $345.00
IHC of DRP-2 (P510) pAb in paraffin-embedded human brain tissue.
Western blot of DRP-2 (P510) pAb in extracts from A549 cells treated with EGF 200ng/ml 30'.

DPYSL2 / CRMP2 Antibody LS-C769137
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC-P, WB
Unconjugated
20µl 1mg/ml  $205.00; 60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

DPYSL2 / CRMP2 Antibody LS-C664803
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Human
ELISA, IHC, IP, WB
Unconjugated
100µg  $335.00

DPYSL2 / CRMP2 Antibody (phospho-Thr509) LS-C198844
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain, using CRMP-2 (Phospho-Thr509) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of lysates from HT29 cells treated with heat shock, using CRMP-2 (Phospho-Thr509) Antibody. The lane on the right is blocked with the phospho peptide.

DPYSL2 / CRMP2 Antibody (450-530 aa) LS-C381405
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of Phospho-CRMP-2 (T509) antibody

DPYSL2 / CRMP2 Antibody (450-530 aa) LS-C382900
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of CRMP-2 antibody

DPYSL2 / CRMP2 Antibody LS-C402205
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl 0.4mg/ml  $205.00; 60µl 0.4mg/ml  $235.00; 120µl 0.4mg/ml  $295.00; 200µl 0.4mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human colon cancer using DPYSL2 Polyclonal Antibody at dilution of 1:45.
Western blot analysis of NIH/3T3 cell, using DPYSL2 Polyclonal Antibody at dilution of 1:400.

DPYSL2 / CRMP2 Antibody LS-C771974
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Showing 1-25 of 51 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).