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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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DPYSL2 / CRMP2

dihydropyrimidinase-like 2

DPYSL2 / CRMP2 is a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: dihydropyrimidinase-like 2
Synonyms: DPYSL2, CRMP2, CRMP-2, DHPRP2, Dihydropyrimidinase-like 2, DRP-2, N2A3, ULIP2, ULIP-2, Unc-33-like phosphoprotein 2
Target Sequences: NM_001386 NP_001377.1 Q16555

Publications (2)

1
Glyoxalase 1-knockdown in human aortic endothelial cells - effect on the proteome and endothelial function estimates. Stratmann B, Engelbrecht B, Espelage BC, Klusmeier N, Tiemann J, Gawlowski T, Mattern Y, Eisenacher M, Meyer HE, Rabbani N, Thornalley PJ, Tschoepe D, Poschmann G, Stühler K. Scientific reports. 2016 6:37737. (WB; Human) [Full Text Article] [PubMed:27898103] [PMC:PMC5127188] Related Antibodies: LS-B3616.
2
PACAP stimulates functional recovery after spinal cord injury through axonal regeneration. Tsuchida M, Nakamachi T, Sugiyama K, Tsuchikawa D, Watanabe J, Hori M, Yoshikawa A, Imai N, Kagami N, Matkovits A, Atsumi T, Shioda S. Journal of molecular neuroscience : MN. Nov;54:380-7. [Full Text Article] [PubMed:25074795] Related Antibodies: LS-B5657.


DPYSL2 / CRMP2 Antibody - Anti-CRMP-2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
DPYSL2 / CRMP2 Antibody - Anti-CRMP-2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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Mouse Monoclonal [clone 33CT11.40.3] (IgG2b) to Human DPYSL2 / CRMP2
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200µl   $425.00
DPYSL2 / CRMP2 Antibody - Anti-DPYSL2 / CRMP2 antibody IHC staining of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Monoclonal [clone EPR7792] (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
50µl   $425.00
DPYSL2 / CRMP2 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100µl   1mg/ml   $505.00
DPYSL2 / CRMP2 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100µl   1mg/ml   $505.00
DPYSL2 / CRMP2 Antibody - Immunofluorescence of monoclonal antibody to DPYSL2 on HeLa cell . [antibody concentration 10 ug/ml]
Select
Mouse Monoclonal [clone 1F11] (IgG2a,k) to Human DPYSL2 / CRMP2
Human
ELISA, IF, WB
Unconjugated
100µg   $365.00
DPYSL2 / CRMP2 Antibody - Western blot of DRP-2 phosphorylation expression in PMA treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Select
Rabbit Polyclonal to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50µg   50µl   1mg/ml   $255.00; 100µg   100µl   1mg/ml   $305.00
DPYSL2 / CRMP2 Antibody - Immunohistochemistry image of paraffin-embedded human brain tissue at a dilution of 1:100
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
DPYSL2 / CRMP2 Antibody - 1/100 staining human brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary antibody.
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
DPYSL2 / CRMP2 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using DRP-2 (Phospho-Thr514) antibody.
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $305.00
DPYSL2 / CRMP2 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human braIin tissue using DRP-2 (Ab-514) antibody.
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $305.00
DPYSL2 / CRMP2 Antibody - 1/100 staining human brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary antibody.
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
DPYSL2 / CRMP2 Antibody - Western blot of DRP-2 expression in EGF treated A549 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Select
Rabbit Polyclonal to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50µg   50µl   1mg/ml   $255.00; 100µg   100µl   1mg/ml   $305.00
DPYSL2 / CRMP2 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using DRP-2 (Phospho-Thr514) Antibody. The picture on the right is blocked with the phospho peptide.
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $335.00
DPYSL2 / CRMP2 Antibody - Western blot of CRMP-2 antibody
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
DPYSL2 / CRMP2 Antibody - Western blot of Phospho-CRMP-2 (T514) antibody
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
DPYSL2 / CRMP2 Antibody - Immunofluorescence staining of DPYSL2 in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human DPYSL2 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 594-conjugated Goat Anti-rabbit IgG secondary antibody (red) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Human
ICC, IF, IP, WB
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
DPYSL2 / CRMP2 Antibody - IHC of DRP-2 (P510) pAb in paraffin-embedded human brain tissue.
Select
Rabbit Polyclonal to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
100µl   $345.00
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IF, IHC-P, WB
Unconjugated
20µl   1mg/ml   $205.00; 60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Human
ELISA, IHC, IP, WB
Unconjugated
100µg   $335.00
DPYSL2 / CRMP2 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using CRMP-2 (Phospho-Thr509) Antibody. The picture on the right is blocked with the phospho peptide.
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
DPYSL2 / CRMP2 Antibody - Western blot of Phospho-CRMP-2 (T509) antibody
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
DPYSL2 / CRMP2 Antibody - Western blot of CRMP-2 antibody
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
DPYSL2 / CRMP2 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using CRMP-2 (Ab-509) antibody.
Select
Rabbit Polyclonal (IgG) to Human DPYSL2 / CRMP2
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   $305.00
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).