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DPP2 / DPP7 is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH.
Gene Name: | dipeptidyl-peptidase 7 |
Family/Subfamily: | Protease , Serine S28 |
Synonyms: | DPP7, Carboxytripeptidase, Dipeptidyl aminopeptidase II, Dipeptidyl peptidase 2, DPPII, Dipeptidyl arylamidase II, Dipeptidyl-peptidase 7, Dipeptidyl-peptidase II, Dipeptidylpeptidase 7, Dipeptidyl peptidase 7, Dipeptidyl peptidase II, DPP II, DPP2, QPP |
Target Sequences: | NM_013379 NP_037511.2 Q9UHL4 |
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