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DBI / ACBD1

diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)

EP / DBI is diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Gene Name: diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
Synonyms: DBI, ACBP, Acyl-CoA-binding protein, CCK-RP, ACBD1, GABA receptor modulator, EP, Endozepine
Target Sequences: NM_020548 NP_065438.1 P07108

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Products
Antibodies (50)
Primary (50)
DBI / ACBD1 (50)
Human (42)
Mouse (26)
Rat (14)
Chimpanzee (3)
Gibbon (6)
Monkey (6)
Orangutan (6)
Pig (4)
IHC (12)
IHC-Fr (1)
IHC-P (5)
WB (46)
Flo (1)
ELISA (12)
ICC (1)
IF (3)
IP (2)
Peptide-ELISA (2)
rabbit (48)
mouse (2)
Product Group
IHCPlus (2)
IgG (23)
IgG1,k (1)
IgG2b,k (1)
monoclonal mc (2)
polyclonal pc (48)
APC (2)
APC Conjugated (3)
Biotin Conjugated (6)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (3)
Preservative Free (1)
Unconjugated (22)
N-Terminus (8)
aa1-87 (8)
aa2-87 (8)
C-Terminus (1)
C-terminal (1)
Internal (1)
aa2-105 (1)
aa25-74 (1)
No (50)
DBI / ACBD1 Antibody
Select
DBI / ACBD1 Rabbit anti-Human Polyclonal (aa1-87) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596
DBI / ACBD1 Antibody - DBI antibody Western blot of HT1080 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DBI / ACBD1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
DBI / ACBD1 Antibody - Immunohistochemistry of paraffin-embedded human prostate using DBI Antibody at dilution of 1:100 (40x lens).
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DBI / ACBD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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DBI / ACBD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
DBI / ACBD1 Antibody - IHC analysis of DBI using anti-DBI antibody. DBI was detected in paraffin-embedded section of human prostatic cancer tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-DBI Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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DBI / ACBD1 Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, IHC-Fr, WB
Unconjugated
10 µg/$318; 100 µg/$470
DBI / ACBD1 Antibody - Anti-DBI antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DBI / ACBD1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
DBI / ACBD1 Antibody - Anti-DBI antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DBI / ACBD1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Pig, Orangutan, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
DBI / ACBD1 Antibody - Anti-DBI antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DBI / ACBD1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Pig, Orangutan, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
DBI / ACBD1 Antibody - Anti-DBI antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DBI / ACBD1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Pig, Orangutan, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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DBI / ACBD1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$562
DBI / ACBD1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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DBI / ACBD1 Rabbit anti-Human Polyclonal (aa2-105) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
Select
DBI / ACBD1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
DBI / ACBD1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
DBI / ACBD1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
DBI / ACBD1 Antibody - Immunofluorescence analysis of MCF-7 cells.
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DBI / ACBD1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
DBI / ACBD1 Antibody - Western blot of ACBP antibody
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DBI / ACBD1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DBI / ACBD1 Antibody - Immunohistochemistry analysis of ACBP antibody in paraffin-embedded human liver carcinoma tissue.
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DBI / ACBD1 Rabbit anti-Human Polyclonal (aa25-74) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
DBI / ACBD1 Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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DBI / ACBD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
DBI / ACBD1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IP
Unconjugated
100 µg/$562
Select
DBI / ACBD1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
DBI / ACBD1 Antibody - Western blot analysis of lysate from MCF7 cells, using DBI Antibody.
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DBI / ACBD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
DBI / ACBD1 Antibody - Western blot of ACBP antibody
Select
DBI / ACBD1 Rabbit anti-Human Polyclonal (C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DBI / ACBD1 Antibody - Western blot of recombinant EP / DBI.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
DBI / ACBD1 Rabbit anti-Mouse Polyclonal (aa2-87) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
Select
DBI / ACBD1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
DBI / ACBD1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).