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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CYP11B2 / Aldosterone Synthase

cytochrome P450, family 11, subfamily B, polypeptide 2

CYP11B2 / Aldosterone Synthase is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Gene Name: cytochrome P450, family 11, subfamily B, polypeptide 2
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP11B2, ALDOS, Aldosterone synthase, CYP11BL, CYPXIB2, Cytochrome P-450Aldo, Cytochrome P-450C18, P-450C18, p450aldo, Steroid 18-hydroxylase, Steroid 11-beta-monooxygenase, CYP11B, p450C18, Steroid 11-beta/18-hydroxylase
Target Sequences: NM_000498 NP_000489.3 P19099

Filtered By: None
Target
CYP11B2 / Aldosterone Synthase (20)
Reactivity
Human (19)
Mouse (10)
Rat (2)
Application
IHC (10)
IHC-P (1)
WB (16)
Flo (7)
ELISA (12)
ICC (1)
IF (1)
Host
rabbit (19)
mouse (1)
Isotype
IgG (17)
IgG1,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (19)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (8)
Epitope
aa120-147 (7)
C-Terminus (4)
Internal (1)
aa175-192 (1)
Publications
No (19)
Yes (1)
Showing 1-20 of 20 results

CYP11B2 / Aldosterone Synthase Antibody (aa175-192) LS-C6353
Publications (1)
Publications (1)
Mouse Monoclonal (IgG1,k) to Rat CYP11B2 / Aldosterone Synthase
Rat
ELISA ICC IHC IHC-P WB
Unconjugated
500µl  $605.00

CYP11B2 / Aldosterone Synthase Antibody (C-Terminus) LS-C107630
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human
WB
Unconjugated
50µg  $365.00
CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

CYP11B2 / Aldosterone Synthase Antibody (C-Terminus, HRP) LS-C442680
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

CYP11B2 / Aldosterone Synthase Antibody (C-Terminus, Biotin) LS-C442678
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

CYP11B2 / Aldosterone Synthase Antibody (C-Terminus, FITC) LS-C442679
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human
WB
FITC Conjugated
100µl 1mg/ml  $385.00
CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
CYP11B2 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

CYP11B2 / Aldosterone Synthase Antibody LS-C664922
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human
ELISA IF IHC WB
Unconjugated
100µg  $355.00

CYP11B2 / Aldosterone Synthase Antibody (aa120-147) LS-C320713
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Mouse, Human
Flo IHC WB
Unconjugated
200µl  $530.00

CYP11B2 / Aldosterone Synthase Antibody (aa120-147, Biotin) LS-C208749
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Mouse, Human
ELISA Flo IHC WB
Biotin Conjugated
200µl  $680.00

CYP11B2 / Aldosterone Synthase Antibody (aa120-147, FITC) LS-C208750
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Mouse, Human
ELISA Flo IHC WB
FITC Conjugated
200µl  $680.00

CYP11B2 / Aldosterone Synthase Antibody (aa120-147, APC) LS-C208748
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Mouse, Human
ELISA Flo IHC WB
APC Conjugated
200µl  $680.00

CYP11B2 / Aldosterone Synthase Antibody (aa120-147, Azide-free, HRP) LS-C208751
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Mouse, Human
ELISA Flo IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

CYP11B2 / Aldosterone Synthase Antibody (aa120-147, AP) LS-C208747
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Mouse, Human
ELISA Flo IHC WB
AP Conjugated
200µl  $680.00

CYP11B2 / Aldosterone Synthase Antibody (aa120-147, PE) LS-C208752
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Mouse, Human
ELISA Flo IHC WB
PE Conjugated
200µl  $680.00

CYP11B2 / Aldosterone Synthase Antibody LS-C498545
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human
ELISA IHC
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human kidney tissue using CYP11B2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CYP11B2 Antibody at dilution of 1:100

CYP11B2 / Aldosterone Synthase Antibody (HRP) LS-C498546
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

CYP11B2 / Aldosterone Synthase Antibody (Biotin) LS-C498547
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

CYP11B2 / Aldosterone Synthase Antibody (FITC) LS-C498565
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00

CYP11B2 / Aldosterone Synthase Antibody (Internal) LS-C354331
Rabbit Polyclonal to Human CYP11B2 / Aldosterone Synthase
Mouse, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of Cytochrome P450 11B2 expression in HEK293T (A); Raw264.7 (B) whole cell lysates.
Western blot analysis of Cytochrome P450 11B2 expression in HEK293T (A); Raw264.7 (B) whole cell lysates.

CYP11B2 / Aldosterone Synthase Antibody LS-C411832
Rabbit Polyclonal to Human CYP11B2 / Aldosterone Synthase
Mouse, Human
WB
Unconjugated
100µl 1mg/ml  $385.00
Western blot of CYP11B2 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate.
Western blot of CYP11B2 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate.

CYP11B2 / Aldosterone Synthase Antibody LS-C408316
Rabbit Polyclonal (IgG) to Human CYP11B2 / Aldosterone Synthase
Mouse, Rat, Human
WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of various cell lines, using CYP11B2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 20s.
Western blot analysis of extracts of various cell lines, using CYP11B2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 20s.
Showing 1-20 of 20 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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