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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-C6353-500 500 µl $620 
Antibody

Monoclonal Mouse anti‑Rat CYP11B2 / Aldosterone Synthase Antibody (aa175‑192, IHC, WB) LS‑C6353

Monoclonal Mouse anti‑Rat CYP11B2 / Aldosterone Synthase Antibody (aa175‑192, IHC, WB) LS‑C6353

Antibody:
Mouse Monoclonal to Rat CYP11B2 / Aldosterone Synthase
Application:
IHC, IHC-P, ICC, WB, ELISA
Reactivity:
Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$620 
LS-C6353-500
500 µl
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Mouse Monoclonal to Rat CYP11B2 / Aldosterone Synthase
Application:
IHC, IHC-P, ICC, WB, ELISA
Reactivity:
Rat
Format:
Unconjugated, Unmodified

Specifications

Description
Aldosterone Synthase antibody LS-C6353 is an unconjugated mouse monoclonal antibody to rat Aldosterone Synthase (CYP11B2) (aa175-192). Validated for ELISA, ICC, IHC and WB. Cited in 1 publication.
Target
Rat CYP11B2 / Aldosterone Synthase
Synonyms
CYP11B2 | ALDOS | Aldosterone synthase | CYP11BL | CYPXIB2 | Cytochrome P-450Aldo | Cytochrome P-450C18 | P-450C18 | p450aldo | Steroid 18-hydroxylase | Steroid 11-beta-monooxygenase | CYP11B | p450C18 | Steroid 11-beta/18-hydroxylase
Host
Mouse
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:200)
  • ICC (1:20 - 1:200)
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Rat Aldo-1-MAP aa175-192 (KVRQNARGSLTMDVQQSL-MAP). Percent identity by BLAST analysis: Rat (100%); Mouse, Hamster (94%); Gorilla (83%).
Epitope
aa175-192
Specificity
Recognizes rat cytochrome p450 aldosterone synthase. Species cross-reactivity: Mouse.
Usage
Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA. Immunohistochemistry: STF on paraffin embedded tissue. Requires Microwave or pressure cooker antigen retrieval. Recommended counter stain is Gill's Hematoxylin.
Presentation
0.09% Sodium Azide, 50% Glycerol
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CYP11B2 / Aldosterone Synthase
P19099 NM_000498 NP_000489.3

LSBio Ratings

CYP11B2 / Aldosterone Synthase Antibody (aa175-192) for IHC, ICC, WB/Western, ELISA LS-C6353 has an LSBio Rating of
Publications (4)

Publications (1)

Transgenic GATA-4 expression induces adrenocortical tumorigenesis in C57Bl/6 mice. Chrusciel M, Vuorenoja S, Mohanty B, Rivero-M[Character fc]ller A, Li X, Toppari J, Huhtaniemi I, Rahman NA. Journal of cell science. 2013 Apr;126:1845-57.

Customer Reviews (0)


Requested From: United States
Date Requested: 7/11/2020